2,256 results match your criteria: "Hubei University of Technology[Affiliation]"

Effective xylan integration for remodeling biochar uniformity and porosity to enhance chemical elimination and CO adsorption.

Int J Biol Macromol

December 2024

College of Plant Science & Technology, Huazhong Agricultural University, Wuhan 430070, China; Key Laboratory of Fermentation Engineering (Ministry of Education), Hubei Key Laboratory of Industrial Microbiology, School of Life & Health Sciences, Hubei University of Technology, Wuhan 430068, China. Electronic address:

Although plant evolution has offered diverse biomass resources, the production of high-quality biochar from desirable lignocelluloses remains unexplored. In this study, distinct lignocellulose substrates derived from eight representative plant species were employed to prepare biochar samples under three different temperature treatments. Correlation analysis showed that only hemicellulose was a consistently positive factor of lignocellulose substrates to account for the dye-adsorption capacities of diverse biochar samples.

View Article and Find Full Text PDF

Rice husk ash is an industrial waste produced by biomass power plant to generate electricity, which contains a lot of silica. The accumulation of rice husk ash not only consumes land resources, but also causes environmental pollution. It is an urgent problem to explore the resource utilization of rice husk ash.

View Article and Find Full Text PDF

Introduction: This study explores the nuanced relationship between teachers' teaching strategies and students' learning engagement within online environments, considering the mediation by students' perceptions of teachers' emotional engagement and the moderation by teachers' expectations.

Methods: Employing a stratified sampling technique, data were collected from 1,200 Chinese primary and secondary students through the "Survey on Online Learning Engagement." Structural equation modeling was applied to analyze the relationships among teaching strategies, emotional engagement, teachers' expectations, and learning engagement.

View Article and Find Full Text PDF

Reprograming the Carbon Metabolism of Yeast for Hyperproducing Mevalonate, a Building Precursor of the Terpenoid Backbone.

J Agric Food Chem

January 2025

Key Laboratory of Engineering Biology for Low-Carbon Manufacturing, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China.

Utilization of microbial hosts to produce natural plant products is regarded as a promising and sustainable approach. However, achieving highly efficient production of terpenoids using microorganisms remains a significant challenge. Here, mevalonate, a building block of terpenoids, was used as a demo product to explore the potential metabolic constraints for terpenoid biosynthesis in .

View Article and Find Full Text PDF

Semi-rational design and modification of phosphoketolase to improve the yield of tyrosol in .

Synth Syst Biotechnol

November 2024

Cooperative Innovation Center of Industrial Fermentation (Ministry of Education & Hubei Province), Key Laboratory of Fermentation Engineering (Ministry of Education), National "111" Center for Cellular Regulation and Molecular Pharmaceutics, Hubei Key Laboratory of Industrial Microbiology, School of Life and Health Sciences, Hubei University of Technology, Wuhan, Hubei, 430068, PR China.

Tyrosol is an important component of pharmaceuticals, nutraceuticals, and cosmetics, and their biosynthetic pathways are currently a hot research topic. d-Erythrose 4-phosphate is a key precursor for the biosynthesis of tyrosol in . Hence, the flux of d-Erythrose 4-phosphate determined the yield of tyrosol synthesis.

View Article and Find Full Text PDF

In this study, homoisoflavone methylophiopogonanone A (MOA) was investigated for its inhibitory effect on ferroptosis of H9c2 cells using a set of cellular assays, such as BODIPY-probed and HDCFDA-probed flow cytometry analyses, cell counting kit-8 analysis (CCK-8), and lactate dehydrogenase (LDH) release analysis. All these cellular assays adopted Fer-1 as the positive control. Subsequently, MOA and Fer-1 were subjected to two antioxidant assays, i.

View Article and Find Full Text PDF

Pea-Protein-Stabilized Emulsion as a High-Performance Cryoprotectant in Frozen Dough: Effects on the Storage Stability and Baking Performance.

Foods

November 2024

Key Laboratory of Fermentation Engineering (Ministry of Education), Hubei Key Laboratory of Industrial Microbiology, Cooperative Innovation Center of Industrial Fermentation (Ministry of Education & Hubei Province), National "111" Center for Cellular Regulation and Molecular Pharmaceutics, Hubei University of Technology, Wuhan 430068, China.

The use of oil-in-water (O/W) emulsion has drawn increasing attention in the baking industry. Compared with some of the well-recognized functionalities, such as textural improvers and flavor carriers, its cryoprotective behavior in frozen dough has not been extensively investigated. Herein, this study reported a pea-protein (PP)-stabilized O/W emulsion with good freeze-thaw stability and evaluated its effectiveness as a high-performance dough cryoprotectant.

View Article and Find Full Text PDF

Enhanced multistress tolerance of with the sugar transporter-like protein Stl1 mutation in the presence of glycerol.

Microbiol Spectr

December 2024

Key Laboratory of Fermentation Engineering (Ministry of Education), Cooperative Innovation Center of Industrial Fermentation (Ministry of Education & Hubei Province), School of Bioengineering and Food Science, Hubei University of Technology, Wuhan, Hubei, China.

Unlabelled: During microbial industrial production, microorganisms often face diverse stressors, including organic solvents, high salinity, and high sugar levels. Enhancing microorganism tolerance to such stresses is crucial for producing high-value-added products. Previous studies on the mechanisms of 2-phenylethanol (2-PE) tolerance in revealed a potential connection between the sugar transporter-like protein (Stl1) mutation (F427L) and increased tolerance to high sugar and salt stress, suggesting a broader role in multistress tolerance.

View Article and Find Full Text PDF

ZIKV prM hijacks PIM1 kinase for phosphorylation to prevent ubiquitin-mediated degradation and facilitate viral replication.

Front Cell Infect Microbiol

December 2024

State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, Hubei, China.

Introduction: Viral infection usually stimulates a variety of host cell factors to modulate the life cycle of the virus. PIM1, a serine/threonine protein kinase widely involved in cell proliferation, survival, differentiation and apoptosis, was recently reported to be upregulated by Zika virus (ZIKV) infection. However, how ZIKV-PIM1 interactions affect the viral life cycle are not fully understood.

View Article and Find Full Text PDF

Due to its high viscoelasticity and positive health benefits, konjac glucomannan (KGM)-based mixed polysaccharide systems are widely applied in food processing and pharmaceuticals. However, a knowledge gap exists between the relationship between KGM interactions with different polysaccharides and the resulting food processing properties and health benefits. This review elaborately aims to address this research gap by analyzing the literature on the updated KGM-based binary thermodynamic compatibility systems, classified and discussed according to the basic gel models.

View Article and Find Full Text PDF

Exploring the promising potential of alcohol extract from the aerial part of dill in ameliorating DSS-induced ulcerative colitis in mice.

J Ethnopharmacol

January 2025

Key Laboratory of Fermentation Engineering (Ministry of Education), Cooperative Innovation Center of Industrial Fermentation (Ministry of Education & Hubei Province), School of Life and Health Sciences, Hubei University of Technology, 430068, Wuhan, China. Electronic address:

Ethnopharmacological Relevance: Dill (Anethum graveolens L.) is a typical Uyghur medicine. It is traditionally used to treat sticky and stagnant dampness, hiccups and food stagnation, intestinal obstruction, and anorectal diseases.

View Article and Find Full Text PDF

Assessment of technology adoption in construction safety management: Case study in China.

Sci Prog

December 2024

School of Civil Engineering, Architecture and Environment, Hubei University of Technology, Wuhan, China.

The current body of literature indicates that the utilization of emerging digital safety technologies has the potential to enhance the efficacy of safety management in construction significantly. Nevertheless, there has been limited uptake of digital safety technologies within the construction industry in developing countries. This study is focused on evaluating the adoption of digital safety technologies in construction specifically from the perspective of developing countries.

View Article and Find Full Text PDF

Effect of black highland barley polysaccharides and low frequency-static magnetic field on casein-based coacervates: Formation, characterization, and probiotic encapsulation capacity.

Int J Biol Macromol

January 2025

Cooperative Innovation Center of Industrial Fermentation (Ministry of Education & Hubei Province), Hubei University of Technology, Wuhan 430068, China; School of Life and Health Sciences, Hubei University of Technology, Wuhan 430068, China. Electronic address:

To evaluate the combination effects of highland barley polysaccharides (HBP) and low-frequency static magnetic field (LF-SMF) treatment on the structure and properties of acid-induced casein (CS) coacervates, this study conducted a comprehensive investigation at various stages- before, during, and after coacervation-for the first time. Compared with native CS, adding HBP caused CS to denature owing to hydrophobic and electrostatic interactions, and LF-SMF treatment further promoted these changes. During the acidification (pH 7.

View Article and Find Full Text PDF

As the proportion of the aging population globally is surging year by year, age-associated diseases, including neurodegenerative, metabolic, and cardiovascular diseases, have recently attracted widespread attention of food scientists and nutritionists. Polymethoxyflavonoids (PMFs), a type of dietary flavonoids, have emerged as potential antiaging candidates owing to their diverse bioactivities, encompassing antioxidant, anti-inflammatory, neuroprotective, and metabolic regulatory effects. Herein, this comprehensive updated review has summarized and discussed the effects of PMFs on aging, and the possible mechanisms that link PMFs-mediated modulation and the prevention or treatment of various aging-related diseases have been elaborated in detail.

View Article and Find Full Text PDF

Hydrogen/Electron Amphiphilic Bi-Functional Water Molecular Inactivator-Assisted Interface Stabilization in Highly Reversible Zn Metal Batteries.

Angew Chem Int Ed Engl

December 2024

State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan, 430070, China.

Article Synopsis
  • A continuous hydrogen-bond-network in aqueous electrolytes can cause unwanted hydrogen transfer and side reactions in aqueous zinc metal batteries (AZMBs), which complicates their efficiency.
  • The introduction of the 1,5-Pentanediol (PD) molecule stabilizes the electrode/electrolyte interface by breaking up hydrogen-bonding in water, enhancing electron acceptance, and promoting favorable interactions with the electrode material.
  • This leads to improved zinc deposition, formation of a protective solid-electrolyte interphase (SEI), and a significant extension of cycling performance, with Zn//Zn cells exhibiting over 5600 hours of stable operation.
View Article and Find Full Text PDF

The effect of pH on structural properties and interaction mechanisms of zein/epicatechin gallate complexes.

Food Chem X

December 2024

Cooperative Innovation Center of Industrial Fermentation (Ministry of Education & Hubei Province), Key Laboratory of Fermentation Engineering (Ministry of Education), National "111" Center for Cellular Regulation and Molecular Pharmaceutics, Hubei University of Technology, Wuhan 430068, China.

This study aimed to investigate the effects of pH on the structural properties and interaction mechanisms of zein/epicatechin gallate (ECG) complexes. QCM-D data demonstrated that the binding capacity of ECG to zein was significantly higher under alkaline condition (pH 9) compared to neutral and acidic conditions ( < 0.05).

View Article and Find Full Text PDF

Understanding the role of hormones in pediatric growth: Insights from a double-debiased machine learning approach.

Steroids

December 2024

Department/Institution: College of Economics and Management, Huazhong Agricultural University, No.1 Shizishan Street, Hongshan District, Wuhan, Hubei Province 430070, China. Electronic address:

This study investigates the causal relationships between hormone levels and growth and development of children, focusing specifically on height disparities in cases of dwarfism. Besides utilizing double-debiased machine learning approach, the study integrates three alternative causal inference methods: partialing-out lasso linear regression, cross-fit partialing-out lasso linear regression, and post-double selection LASSO. These machine learning techniques are pivotal in identifying causal effects within observational data.

View Article and Find Full Text PDF

Development and application of an uncapped mRNA platform.

Ann Med

December 2025

College of Bioengineering, National ''111'' Center for Cellular Regulation and Molecular Pharmaceutics, Key Laboratory of Fermentation Engineering (Ministry of Education), Hubei Provincial Cooperative Innovation Center of Industrial Fermentation, Hubei University of Technology, Wuhan, China.

Article Synopsis
  • A novel uncapped mRNA platform was created to enhance transfection efficiency and immune response, using lipid nanoparticle (LNP) technology.
  • Five different mRNA constructs were tested, leading to measurable protein expression and robust immune responses in various animal models, particularly targeting COVID-19 and HSV2.
  • The platform, which simplifies the mRNA synthesis process, shows promise for potential applications in vaccines and therapeutic proteins, outperforming traditional constructs in immunity induction.
View Article and Find Full Text PDF

Poly(vinylidene fluoride) (PVDF) membranes with highly hydrophilic and antifouling properties are desirable for oily wastewater treatment. Herein, we report (1) a strategy of bulk modification of PVDF by integration of PVDF and a particle-based double-network (PDN) hydrogel, poly-2-acrylamido-2-methylpropanesulfonate/polyacrylamide (PAMPS/PAAm), via a strong PDN and PVDF interpenetrating polymer network (PDN-PVDF IPN) to obtain a PVDF/PDN solution and (2) the subsequent casting of it into a microfiltration membrane via spray-assisted non-solvent-induced phase separation (SANIPS). The IPN structure modulates the surface segregation behavior of the highly hydrophilic and robust PDN hydrogel in the process of SANIPS, endowing the resulting PVDF/PDN membrane with excellent bulk mechanical properties and much enhanced wettability and thereby high oil/water emulsion separation efficiency and antifouling performance.

View Article and Find Full Text PDF

Multiple factors on driving load in mountain area at night based on factor analysis.

PLoS One

December 2024

School of Civil Engineering Architecture and the Environment, Hubei University of Technology, Wuhan, China.

Different driving environments may lead to increased mental workload and fatigue among drivers, consequently diminishing driving safety. To investigate the impact of various factors on drivers' driving load, this study approaches the issue from three perspectives: external weather environment, road driving environment, and in-vehicle driving environment. Through the experimental modeling of the mountainous road section of Provincial Highway S208 in Chongyang County, Xianning City, and employing simulated driving experiments, various factor combinations were designed to investigate the visual characteristics of drivers.

View Article and Find Full Text PDF

Exploiting conjugated linoleic acid for health: a recent update.

Food Funct

January 2025

Hubei Key Laboratory of Industrial Microbiology, Cooperative Innovation Center of Industrial Fermentation (Ministry of Education & Hubei Province), Key Laboratory of Fermentation Engineering (Ministry of Education), National "111" Center for Cellular Regulation and Molecular Pharmaceutics, Hubei University of Technology, Wuhan, Hubei, 430068, China.

Conjugated linoleic acid (CLA) is widely used as a dietary supplement due to its reported benefits in enhancing immunity, regulating inflammation, treating obesity, and preventing cancer. However, there is a lack of comprehensive studies on its mechanisms and dose-effect relationships. Moreover, there are insufficient in-depth studies on CLA's new functions, safety, side effects, and clinical utility.

View Article and Find Full Text PDF

The quality of underwater images is often affected by light scattering and attenuation, resulting in a loss of contrast and brightness. To address this issue, this paper proposes an underwater image enhancement method: improved Fick's law algorithm-based optimally weighted histogram framework (IFLAHF). The method incorporates the bi-histogram equalization-based three plateau limits (BHE3PL) technique to enhance image contrast and details while maintaining brightness.

View Article and Find Full Text PDF

TRPM channels in human cancers: regulatory mechanism and therapeutic prospects.

Biomark Res

December 2024

National "111" Center for Cellular Regulation and Molecular Pharmaceutics, Key Laboratory of Fermentation Engineering (Ministry of Education), Cooperative Innovation Center of Industrial Fermentation (Ministry of Education & Hubei Province), Hubei Key Laboratory of Industrial Microbiology, Hubei University of Technology, Wuhan, 430074, China.

The transient receptor potential melastatin (TRPM) channel family has been previously implicated in various diseases, including those related to temperature sensing, cardiovascular health, and neurodegeneration. Nowadays, increasing evidence indicates that TRPM family members also play significant roles in various types of cancers, exhibiting both pro- and anti-tumorigenic functions. They are involved in tumor cell proliferation, survival, invasion, and metastasis, serving as potential diagnostic and prognostic biomarkers for cancer.

View Article and Find Full Text PDF

High-performance bifunctional electrocatalyst for oxygen evolution reaction (OER) and oxygen reduction reaction (ORR) is the keystone for the industrialization of rechargeable zinc-air battery (ZAB). In this work, the modulation in the spin state of Fe single atom on nitrogen doped carbon (Fe-NC) is devised by CoO (CoO@Fe-NC), and a mediate spin state is recorded. Besides, the d band center of Fe is downshifted associated with the increment in e filling revealing the weakened interaction with OH moiety, resulting in a boosted ORR performance.

View Article and Find Full Text PDF