6 results match your criteria: "Hubei Third People's Hospital affiliated to Jianghan University[Affiliation]"
The role of bacteria in gallstone formation.
Folia Microbiol (Praha)
February 2024
Health Management (Physical Examination) Section of Hubei Third People's Hospital Affiliated to Jianghan University, Wuhan, 430034, People's Republic of China.
Gallstones are a prevalent biliary system disorder that is particularly common in women. They can lead to various complications, such as biliary colic, infection, cholecystitis, and even gallbladder cancer. However, the etiology of gallstones remains incompletely understood.
View Article and Find Full Text PDFHigh-throughput sequencing-based analysis of the composition and diversity of endophytic bacteria community in tubers of f.glauca.
Front Microbiol
January 2023
Emergency Department of Hubei Third People's Hospital Affiliated to Jianghan University, Wuhan, Hubei Province, China.
f.glauca () is a commonly used Chinese Medicinal Materials with great medicinal value. The medicinal plant and its endophytic bacteria are a symbiotic whole, and the endophytic bacteria are rich in species, and their metabolites are a treasure trove of natural compounds.
View Article and Find Full Text PDFIbuprofen Alleviates Acute Pancreatitis- (AP-) Induced Myocardial Injury by Inhibiting AIM2.
Comput Math Methods Med
July 2022
Emergency Department, Hubei Third People's Hospital Affiliated to Jianghan University, Wuhan, Hubei 430030, China.
Objective: The lack of certain trace elements such as selenium, molybdenum, magnesium or related nutrients in the soil, water quality and food in the disease area, which caused disturbance of myocardium metabolism and resulted in injury and necrosis. The aim of the study was to explore the mechanism of ibuprofen alleviating myocardial injury caused by acute pancreatitis (AP).
Method: We have established AP cell model and rat model.
Palmitic acid declines glucose uptake in HepG2 cells via modulating phosphoglucomutase 1 to repress phosphatidylinositol 3 kinase/protein kinase B and JNK pathways via inducing microRNA-124-3p.
Turk J Biol
April 2022
Department of Cardiovascular Medicine, Hubei Third People's Hospital affiliated to Jianghan University, Wuhan City, China.
Article Synopsis
- Diabetes, particularly type 2 diabetes (T2DM), is linked to insulin resistance (IR), and the research investigates the role of microRNA miR-124-3p in influencing IR and T2DM.
- The study utilized HepG2 cells, creating an IR model with palmitic acid (PA) and assessed the effects of miR-124-3p and phosphoglucomutase 1 (PGM1) on glucose uptake, cell viability, and various signaling pathways involved in metabolism.
- Findings indicated that miR-124-3p decreases glucose consumption by targeting PGM1, which alters PI3K/AKT and JNK pathways, suggesting potential therapeutic implications for managing T2DM
miR-335-5p aggravates type 2 diabetes by inhibiting SLC2A4 expression.
Biochem Biophys Res Commun
June 2021
Department of Endocrinology, Hubei Third People's Hospital Affiliated to Jianghan University, Wuhan, 430300, Hubei, China. Electronic address:
Globally, type 2 diabetes (T2D) is the most common chronic disease. It affects approximately 500 million people worldwide. Dysregulation of the solute carrier family 2 member 4 (SLC2A4) gene and miR-335-5p has been associated with T2D progression.
View Article and Find Full Text PDF[Visualization analysis of liver fibrosis diagnosis based on Citespace software].
Zhonghua Gan Zang Bing Za Zhi
January 2021
Department of Clinical Medicine, Hubei University of Traditional Chinese Medicine, Wuhan 430070, China Department of Hepatology, Hubei Third People's Hospital Affiliated to Jianghan University, Wuhan 430033, China.
To explore the research hotspots and development trends in the field of liver fibrosis diagnosis by using visualization methods. The relevant literatures on liver fibrosis diagnosis were downloaded from the China National Knowledge Infrastructure database. CiteSpace 5.
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