4-Fluorobenzyl cyanide, a sterically-hindered solvent expediting interfacial kinetics in lithium-ion batteries.

The electrochemical performance of lithium-ion batteries (LIBs) is plagued by sluggish interfacial kinetics. Fortunately, the Li solvation structure bridges the bulk electrolyte and interfacial chemistry, providing a pathway for promoting electrochemical kinetics in LIBs. Herein, we improve the interfacial kinetics by tuning the Li coordination chemistry based on solvent molecular engineering.

Nano-biosensor for SARS-CoV-2/COVID-19 detection: methods, mechanism and interface design.

The epidemic of coronavirus disease 2019 (COVID-19) was a huge disaster to human society. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which led to COVID-19, has resulted in a large number of deaths. Even though the reverse transcription-polymerase chain reaction (RT-PCR) is the most efficient method for the detection of SARS-CoV-2, the disadvantages (such as long detection time, professional operators, expensive instruments, and laboratory equipment) limit its application.

Acoustery System for Differential Diagnosing of Coronavirus COVID-19 Disease.

Because of the outbreak of coronavirus infection, healthcare systems are faced with the lack of medical professionals. We present a system for the differential diagnosis of coronavirus disease, based on deep learning techniques, which can be implemented in clinics. A recurrent network with a convolutional neural network as an encoder and an attention mechanism is used.

Calculating the absolute binding free energy of the insulin dimer in an explicit solvent.

Insulin is a significant hormone in the regulation of glucose level in the blood. Its monomers bind to each other to form dimers or hexamers through a complex process. To study the binding of the insulin dimer, we first calculate its absolute binding free energy by the steered molecular dynamics method and the confinement method based on a fictitious thermodynamic cycle.

Evaluation of non-targeting, C- or N-pH (low) insertion peptide modified superparamagnetic iron oxide nanoclusters for selective MRI of liver tumors and their potential toxicity in cirrhosis.

Superparamagnetic iron oxide nanoclusters (SPIONs) modified with pH (low) insertion peptide (pHLIP) could be advantageous for magnetic resonance imaging (MRI) diagnosis of liver tumors at the early stage due to their unique responsiveness to the tumor acidic microenvironment when tumor markers are unknown. However, many critical aspects including the effectiveness of selective MRI in liver tumors, types of delivery and the potential safety profile in cirrhosis need to be fully evaluated. In this study, we report the evaluation of non-targeting, C- or N-pHLIP modified SPIONs as the contrast agent for selective MRI of liver tumors and their potential toxicity profile in cirrhosis.

Mechanical properties of γ-graphyne nanotubes.

γ-Graphyne nanotubes (γ-GNTs), which are formed by rolling up a γ-graphyne sheet in a similar way to carbon nanotubes, exhibit unique mechanical properties due to the carbon atoms in the sp and sp hybridized states. In this study, the mechanical properties of γ-GNTs were investigated using molecular dynamics simulations. The effects of the dimensions, temperature, strain rate and the presence of a vacancy on the mechanical properties, , Young's modulus, fracture strength and fracture strain, were comprehensively studied.