2 results match your criteria: "Huazhong University of Science and Technology Wuhan 43000[Affiliation]"

miR-375 is downregulated by promoter hypermethylation in MIN6 insulinoma cells.

Int J Clin Exp Pathol

November 2018

Department of Endocrinology and Metabolism, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology Wuhan 43000, Hubei, P. R. China.

Epigenetics may affect the susceptibility for type 2 diabetes mellitus (T2DM). Aberrant DNA methylation patterns are nowadays recognized as a key epigenetic hallmark of T2DM. Previously, our studies have shown that the hypomethylation of human miR-375 promoter may contribute to the pathogenesis of T2DM.

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Epigenetic regulation of microRNA-375 and its role as DNA epigenetic marker of type 2 diabetes mellitus in Chinese Han population.

Int J Clin Exp Pathol

December 2017

Department of Endocrinology and Metabolism, The First Affiliated Hospital, School of Medicine, Shihezi University Shihezi 832002, Xinjiang, P. R. China.

Epigenetics may affect the susceptibility for type 2 diabetes mellitus (T2DM). Previously, our studies have shown that the hypomethylation of human miR-375 promoter may contribute to the pathogenesis of T2DM. However, the methylation pattern of miR-375 promoter in T2DM is not yet fully understood.

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