1 results match your criteria: "Huashan Hospital Affiliated to Fudan Univeristy[Affiliation]"
[Effect of exogenous interferon gamma on the healing of injured skeletal muscle following injury].
Zhongguo Gu Shang
June 2008
The Fudan University Sports Medicine Center, Department of Sports Medcine & Arthroscopic Surgery, Huashan Hospital Affiliated to Fudan Univeristy, Shanghai 200040, China.
Article Synopsis
- The study aimed to analyze the effects of combining human interferon (hIFNgamma) and human insulin-like growth factor-1 (hIGF-1) on muscle recovery and fibrosis after injury in mice.
- Mice were divided into four groups: one received only hIFNgamma, another only hIGF-1, a third both treatments, and a control group received saline. The researchers monitored muscle tissue at various recovery stages.
- Results showed that hIGF-1 significantly promoted muscle regeneration and reduced fibrosis, while hIFNgamma was particularly effective in reducing fibrotic tissue. The combination of both treatments provided the best results in muscle healing and minimizing fibrosis.