Mitochondrial genome of the Common burrowing snake (Reptilia: Xenodermatidae).

Common burrowing snake is the type species of . The complete mitochondrial genome (mitogenome) sequence of was determined by using a PCR-based method. The total length of mitogenome is 17,165 bp and contains 13 protein-coding genes, 22 tRNA genes, 2 ribosome RNA genes and 2 control regions (CR).

Schiff base derived from thiosemicarbazone and anthracene showed high potential in overcoming multidrug resistance in vitro with low drug resistance index.

Multidrug resistance (MDR) is a huge obstacle in cancer chemotherapeutics. Overcoming MDR is a great challenge for anticancer drug discovery. Here, DNA binding and cytotoxicity of Schiff base L1 and L2 were explored to assess their efficiency in fighting cancer and overcoming the MDR.

Complete mitochondrial genome of the Rufous burrowing snake, (Reptilia: Xenodermatidae).

The complete mitochondrial genome (mitogenome) sequence of was determined by using a PCR-based method. The total length of mitogenome is 17,339 bp and contains 13 protein-coding genes, 22 tRNA genes, 2 ribosome RNA genes and 2 control regions (D-loop). All the protein-coding genes of were distributed on the H-strand, except for the ND6 subunit gene and eight tRNA genes which were encoded on the L-strand.

Crude terpene glycoside component from Radix paeoniae rubra protects against isoproterenol-induced myocardial ischemic injury via activation of the PI3K/AKT/mTOR signaling pathway.

Ethnopharmacological Relevance: Radix paeoniae rubra, also known as chishao (CS), is a frequently used traditional Chinese medicine that can promote blood circulation to remove blood stasis. It has been widely used for the prevention and treatment of cardiovascular diseases in China. Although terpene glycoside (TG), the major component in CS, has been shown to possess cardioprotective properties, the mechanism underlying CS-TG's preventive effect against myocardial ischemia injury is unknown.

Floral nectar of the obligate outcrossing Canavalia gladiata (Jacq.) DC. (Fabaceae) contains only one predominant protein, a class III acidic chitinase.

Floral nectar can affect the fitness of insect-pollinated plants, through both attraction and manipulation of pollinators. Self-incompatible insect-pollinated plants receive more insect visits than their self-compatible relatives, and the nectar of such species might face increased risk of infestation by pathogens carried by pollinators than self-compatible plants. Proteins in nectar (nectarins) play an important role in protecting the nectar, but little is known regarding nectarins in self-incompatible species.

A novel composite hydrogel initiated by Spinacia oleracea L. extract on Hela cells for localized photodynamic therapy.

In this study, the poly (ethylene glycol) double acrylates (PEGDA) was first initiated by Spinacia oleracea L. extract (SOLE) to in situ form a polymer hydrogel shell on Hela cells with near infra-red irradiation. The SOLE was also a natural photosensitizer for photodynamic therapy of tumor.

Selective Sensing of Gas Mixture via a Temperature Modulation Approach: New Strategy for Potentiometric Gas Sensor Obtaining Satisfactory Discriminating Features.

A new strategy to discriminate four types of hazardous gases is proposed in this research. Through modulating the operating temperature and the processing response signal with a pattern recognition algorithm, a gas sensor consisting of a single sensing electrode, i.e.

Optimization and evaluation of Oridonin-loaded Soluplus-Pluronic P105 mixed micelles for oral administration.

In this study, a new type of mixed micelles was developed using Soluplus (SOL) and Pluronic P105 (P105) for the encapsulation of Oridonin (ORN). Oridonin-loaded micelles (ORN-M) were simply prepared using solvent evaporation and characterized for particle size, particle morphology, encapsulation efficiency, and drug loading. In addition, the in vitro drug release behavior of ORN-M was assessed using the widely applied dialysis bag technique.

Preparation and antitumor evaluation of self-assembling oleanolic acid-loaded Pluronic P105/d-α-tocopheryl polyethylene glycol succinate mixed micelles for non-small-cell lung cancer treatment.

Oleanolic acid (OA) is a triterpenoid found in various fruits and vegetables and used in traditional Chinese medicine. OA plays a crucial role in the treatment of several cancers, but poor water solubility, low permeability, and significant efflux have limited its widespread clinical use. Vitamin E-d-α-tocopheryl polyethylene glycol succinate (vitamin E-TPGS) and Pluronic P105 were used to improve the solubility and permeability and to decrease the efflux of OA.

The complete mitochondrial genome of the Xizang hot-spring snake, Wall, 1907 (Reptilia, colubridae).

The Xizang hot-spring snake, (Reptilia, Colubridae), is a relict species of the family Colubridae, which is known only from Tibet, China. In this study, we report the complete mitochondrial genome of this species. The total length of the genome is 17,385 bp, and comprises 13 protein-coding genes, 22 tRNA genes, 2 rRNA genes, and 2 control regions.

Phosphate removal by lead-exhausted bioadsorbents simultaneously achieving lead stabilization.

Low-cost adsorbents have been continuously developed for heavy metal removal, but little information is available concerning the follow-up treatment of the toxic metal-laden adsorbents. In this study, an optional strategy was provided for the further treatment of heavy metal-impregnated low-cost adsorbents through employing them for phosphate retention. The enhancement of phosphate adsorption by the sorbed lead was first validated using several types of raw or modified waste biomass.

Composition and morphology of cuticular wax in blueberry (Vaccinium spp.) fruits.

The chemical composition and morphology of cuticular wax in mature fruit of nine blueberry cultivars were investigated using gas chromatography-mass spectrometry (GC-MS) and scanning electron microscope (SEM). Triterpenoids and β-diketones were the most prominent compounds, accounting for on average 64.2% and 16.

Complete mitochondrial genome of a living wild-type Chinese giant salamander (Amphibia: Cryptobranchidae) in Huangshan.

The Chinese giant salamander, , is the biggest extant amphibian in the world. The population from Huangshan is distinct from other populations. The complete mitochondrial genome of a living wild-type Chinese giant salamander from Huangshan was sequenced.

Complete mitochondrial genome of the Xianggelila Hot-spring snake, (Reptilia, Colubridae).

The Xianggelila hot-spring snake, (Reptilia, Colubridae), is a species of family Colubridae, which is seen only in Shangri-La, Northern Yunnan, China. Herein, the complete mitochondrial genome of this species has been reported. The total length of the genome was 17,327 bp, and composed of 13 protein-coding genes, 22 tRNA genes, 2 rRNA genes and 2 control regions.

Design and optimization of self-nanoemulsifying drug delivery systems for improved bioavailability of cyclovirobuxine D.

Background: The main purpose of this research was to design a self-nanoemulsifying drug delivery system (SNEDDS) for improving the bioavailability of cyclovirobuxine D as a poorly water-soluble drug.

Materials And Methods: Solubility trials, emulsifying studies, and pseudo-ternary phase diagrams were used to screen the SNEDDS formulations. The optimized drug-loaded SNEDDS was prepared at a mass ratio of 3:24:38:38 for cyclovirobuxine D, oleic acid, Solutol SH15, and propylene glycol, respectively.

Floral Nectary Morphology and Proteomic Analysis of Nectar of Liriodendron tulipifera Linn.

Nectar is a primary nutrient reward for a variety of pollinators. Recent studies have demonstrated that nectar also has defensive functions against microbial invasion. In this study, the Liriodendron tulipifera nectary was first examined by scanning electron microscopy, and then the nectar was analyzed by two-dimensional gel electrophoresis and liquid chromatography-tandem mass spectrometry, which led to identification of 42 nectar proteins involved in various biological functions.

[Development ideas of fine pharmaceutical materials of traditional Chinese medicine preparations based on active cluster theory].

The pharmaceutical materials are divided into coarse and fine types in the development of traditional Chinese medicine preparations. Fine materials with clear composition, stable content and high quality control conform to the international development trend of traditional Chinese medicine preparations. In this paper, the status of fine materials was analyzed, and the development ideas were tentatively put forward.

Structural Comparison and Simulation of Pneumococcal Peptidoglycan Hydrolase LytB.

Three-dimensional structural determination combined with comprehensive comparisons with the homologs is a straightforward strategy to decipher the molecular function of an enzyme. However, in many cases it's difficult to obtain the complex structure with the substrate/ligand. Structure-based molecular simulation provides an alternative solution to predict the binding pattern of a substrate/ligand to the enzyme.

Identification and cloning of class II and III chitinases from alkaline floral nectar of Rhododendron irroratum, Ericaceae.

Class II and III chitinases belonging to different glycoside hydrolase families were major nectarins in Rhododendron irroratum floral nectar which showed significant chitinolytic activity. Previous studies have demonstrated antimicrobial activity in plant floral nectar, but the molecular basis for the mechanism is still poorly understood. Two chitinases, class II (Rhchi2) and III (Rhchi3), were characterized from alkaline Rhododendron irroratum nectar by both SDS-PAGE and mass spectrometry.

Rapid and highly selective removal of lead from water using graphene oxide-hydrated manganese oxide nanocomposites.

To overcome the limits of graphene oxide (GO) as a novel sorbent for heavy metal removal (e.g., low sorption selectivity and difficulty in solid-liquid separation), a nanocomposite (HMO@GO) with excellent settling ability (<2min) was fabricated through in situ growing nanosized hydrated manganese oxide (HMO) (10.

Huangshan population of Chinese Zacco platypus (Teleostei, Cyprinidae) harbors diverse matrilines and high genetic diversity.

Six main mitochondrial DNA (mtDNA) lineages have been described in minnow (Zacco platypus) samples obtained from northern, western and southern China. Perdices et al. (2004) predicted that further sampling of other tributaries might discover more lineages of this species.

Nucleic acid-selective light-up fluorescent biosensors for ratiometric two-photon imaging of the viscosity of live cells and tissues.

Rational design of specific ratiometric viscosity probes with small molecular weight is a challenge in practical biotechnology applications. Herein two novel water-soluble, small-molecular ratiometric probes, bearing -methyl benzothiazolium moiety (DSF and DBF), are designed for two-photon fluorescent imaging as a functional of local viscosity. The dye DSF, a light-up fluorescent probe, is sensitive to local viscosity and selectively stains nuclear DNA, which can be used to inspect asynchronous cells under confocal microscopy.

Sequencing and analysis of the complete mitochondrial genome of long-tailed Shrike, (Aves: Laniidae).

The total length of mitochondrial genome of is 16 820 bp and contains 13 protein-coding genes, 22 tRNA genes, 2 rRNA genes and 1 D-loop. The phylogenetic tree of and 12 other closely species belonging to order Passeriformes was built.

Complete mitochondrial genome of oriental magpie-robin (Aves: Muscicapidae).

The total length of mitogenome of is 16 827 bp and contains 13 protein-coding genes, 22 tRNA genes, two rRNA genes and one D-loop. The phylogenetic tree of and 13 other species belonging to Passeriformes was built.