53 results match your criteria: "Huai'an Hospital Affiliated of Xuzhou Medical University and Huai'an Second People's Hospital[Affiliation]"

Malignant gliomas are associated with a high mortality rate. Thus, there is an urgent need for the development of novel targeted therapeutics. Aberrant Hedgehog signaling has been directly linked to glioma.

View Article and Find Full Text PDF

Bakkenolide A inhibits leukemia by regulation of HDAC3 and PI3K/Akt-related signaling pathways.

Biomed Pharmacother

October 2016

Department of Pediatrics, Huai'an First People's Hospital, Affiliated of Nanjing Medical University, No. 6 Beijing Road West, Huai'an, Jiangsu 223300, China. Electronic address:

Leukemia has been the third type of cancer killing many people across the world. Bakkenolide A (Bak), extracted from Petasites tricholobus, has been suggested to against cancer and display protective effects on inflammatory cytokines formation. And increasing evidences suggest that histone deacetylase 3 (HDAC3) plays vital roles in cancer formation and persistence via cell death, apoptosis and inflammation.

View Article and Find Full Text PDF

Objective. This study aimed to evaluate the relationship between branched-chain amino acids (BCAAs), metabolic syndrome (MS), and other cardiovascular (CV) risk factors in middle-aged and elderly Chinese population at high risk for the development of cardiovascular disease (CVD). Methods.

View Article and Find Full Text PDF