Predictors of Using Pharmacists as a Medication Safety Information Resource Among Women of Reproductive Age.

Background: Medication use during pregnancy is prevalent with notable increases in the use of over-the-counter medications. In this era of information proliferation, it is important to understand where women of reproductive age obtain information on medication safety.

Objective: The main objective of this study was to determine the predictive factors associated with the utilization of pharmacists as a medication information safety resource among reproductive age women.

Genomic Insights Into Genetic Basis of Evolutionary Conservatism and Innovation in Frogs.

Examining closely related species evolving in similar environments offers valuable insights into the mechanisms driving phylogenetic conservatism and evolutionary lability. This can elucidate the intricate relationship between inheritance and environmental factors. Nonetheless, the precise genomic dynamics and molecular underpinnings of this process remain enigmatic.

Improving Diversity in a Novel Psoriasis Study: VISIBLE as a Framework for Clinical Trial Quality Improvement.

Importance: Diverse racial and ethnic representation in clinical trials has been limited, not representative of the US population, and the subject of pending US Food and Drug Administration guidance. Psoriasis presentation and disease burden can vary by skin pigmentation, race and ethnicity, and socioeconomic differences. Overall, there are limited primary data on clinical response, genetics, and quality of life in populations with psoriasis and skin of color (SoC).

Evidence of prostate cancer-linked virus zoonoses from biophysical genomic variations.

An ongoing double-blind examination of (mathematically) smooth functional dependences of population-based genomic distributions of single nucleotide polymorphisms (SNPs) on quantified environmental parameters has flagged a SNP that has been associated with prostate cancer for dependence on zoonotic viruses. The SNP rs13091518 is an intergenic variant near the gene/pseudo-gene COX6CP6 on chromosome 3. The risk T allele, which is the major allele in all homeostatic populations considered, clearly demonstrates a negative adaptive force of about -0.

New York State Climate Impacts Assessment Chapter 06: Energy.

Energy plays an integral role in New Yorkers' lives. It powers the economy, moves people and goods, keeps homes and workplaces at a livable temperature, and runs critical infrastructure that keeps people healthy and safe. Reliable energy systems are easy to take for granted, but many aspects of these systems are vulnerable to weather and climate hazards.

The Curious Case of the Disappearing Cancer.

Esophageal cancer, particularly squamous cell carcinoma, poses significant diagnostic challenges due to its aggressive nature and similarity to metaplastic tissue. Accurate diagnosis often requires multiple biopsies and vigilant surveillance, especially in high-risk individuals with conditions such as gastroesophageal reflux disease (GERD) and a history of smoking. We present a 66-year-old female patient with a history of severe GERD and smoking, who underwent routine endoscopy revealing a gastric cardia nodule.

Quality of life and the patient journey in hidradenitis suppurativa.

Hidradenitis suppurativa is a debilitating inflammatory disease with a profound impact on quality of life for affected patients and caregivers. The patient journey in hidradenitis begins with symptom onset and proceeds through diagnosis and treatment. It is fraught with misdiagnosis, lack of awareness, misinformation, and inappropriate treatments that lead to shame, blame, isolation, and medical mistrust.

Disrupting the status quo in psychology training: Centering structural competence in accreditation.

To be responsive to the growing mental health inequities in our communities, we must move beyond incremental changes to our graduate training to bolder, more transformative changes. Such efforts must move beyond targeting our academic, internship, and postdoctoral programs and instead focus on critiquing our accreditation process. Without transformation of accreditation and other macrostructural dynamics in psychology, our training programs will continue to perpetuate the status quo and limit the ability of graduate trainees to adequately address mental health disparities.

Environmental Changes Recorded in Sedimentary Rocks in the Clay-Sulfate Transition Region in Gale Crater, Mars: Results From the Sample Analysis at Mars-Evolved Gas Analysis Instrument Onboard the Mars Science Laboratory Rover.

The rover explored the region between the orbitally defined phyllosilicate-bearing Glen Torridon trough and the overlying layered sulfate-bearing unit, called the "clay-sulfate transition region." Samples were drilled from the top of the fluviolacustrine Glasgow member of the Carolyn Shoemaker formation (CSf) to the eolian Contigo member of the Mirador formation (MIf) to assess in situ mineralogical changes with stratigraphic position. The Sample Analysis at Mars-Evolved Gas Analysis (SAM-EGA) instrument analyzed drilled samples within this region to constrain their volatile chemistry and mineralogy.

Similarity Analysis of Computer-Generated and Commercial Libraries for Targeted Biocompatible Coded Amino Acid Replacement.

Many non-natural amino acids can be incorporated by biological systems into coded functional peptides and proteins. For such incorporations to be effective, they must not only be compatible with the desired function but also evade various biochemical error-checking mechanisms. The underlying molecular mechanisms are complex, and this problem has been approached previously largely by expert perception of isomer compatibility, followed by empirical study.

UOTe: Kondo-Interacting Topological Antiferromagnet in a Van der Waals Lattice.

Since the initial discovery of 2D van der Waals (vdW) materials, significant effort has been made to incorporate the three properties of magnetism, band structure topology, and strong electron correlations-to leverage emergent quantum phenomena and expand their potential applications. However, the discovery of a single vdW material that intrinsically hosts all three ingredients has remained an outstanding challenge. Here, the discovery of a Kondo-interacting topological antiferromagnet is reported in the vdW 5f electron system UOTe.

Organic Products of Fatty Acid and Magnesium Sulfate Mixtures after Gamma Radiolysis: Implications for Missions to Europa.

If ocean-derived materials are present at Europa's surface, they would represent accessible records of ocean chemistry and habitability, but such materials would be further processed by Europa's harsh radiation environment. In this study, saturated fatty acids were precipitated onto a Europa-relevant hydrated magnesium sulfate and exposed to gamma radiation doses up to 2 MGy at -196°C. Alkane chains, with carbon numbers one less than those of the starting fatty acids, were the most abundant radiolysis products in solvent and thermal extracts analyzed by gas chromatography mass spectrometry.

A Half-Century Analysis of Firearm-Related Mortality Trends in the United States: A Retrospective Study Utilizing National Data (1968-2022).

Unlabelled: Background Firearm-related deaths are a substantial public health crisis in America, with studies reporting an increasing rate in the past decade. Effective public health interventions rely on comprehensive information about risk and protective factors.

Aim: This study aims to provide a comprehensive examination of trends in firearm-related deaths over the past 55 years, shedding light on the changing landscape and identifying key risk and protective factors associated with firearm-related deaths in the United States.

A Case of Dengue Fever With Multiserotype IgG Positivity.

Dengue fever is a rapidly spreading mosquito-borne viral disease, increasingly endemic in tropical and subtropical regions. This case report details the clinical presentation of a 52-year-old male who developed severe symptoms shortly after returning from a two-week trip to El Salvador, an area known for dengue endemicity. The patient presented with a five-day history of high-grade fever, malaise, diarrhea, dizziness, and intermittent blurry vision, accompanied by chills, dry cough, headaches, and generalized pain.