Is Area-Level Social Vulnerability Index Associated With Patient-Level Health-Related Social Needs in Hand Surgery?

Background: Social drivers of health (SDOH) are area-level, nonmedical factors that affect health outcomes. By contrast, health-related social needs (HRSNs) are individual patient reported and are being deployed in some payment models. SDOH are often used to broadly represent health disparities of communities through metrics, such as the Social Vulnerability Index (SVI); however, the association of area-level SVI to individual HRSNs has not been well studied in hand surgery, which has implications for addressing social risks to improve health and in quality measurement.

Cannabis oil in treating Parkinson's disease: improvement of motor and non-motor symptoms: a case report.

Parkinson's disease (PD) is characterized by progressive loss of dopaminergic neurons in the substantia nigra pars compacta, which leads to a reduction in the production of dopamine. Medication with levodopa becomes less effective as the disease progresses. Despite the excellent results observed in clinical practice with the medicinal use of Cannabis in the treatment of PD, the level of scientific evidence is still limited due to the small number of studies published in this field.

Community responses to a novel house design: A qualitative study of "Star Homes" in Mtwara, southeastern Tanzania.

Introduction: To evaluate the impact of a novel design "Star Home" on the incidence of malaria, respiratory tract infections and diarrheal diseases among children, randomly selected households in Mtwara, Tanzania were offered a free, new Star Home. Drawing on longitudinal qualitative research that accompanied the Star Homes study, this article describes the experiences of residents and the wider community of living with these buildings.

Methods: A total of four rounds of face-to-face interviews were undertaken with residents of Star Homes (n = 37), control (wattle/daub) homes (n = 21), neighboring households n = 6), community members (n = 17) and community leaders (n = 6).

A linear tessellation model for the identification of "food desert": A case study of Shanghai, China.

The "food desert" problem has been treated under a national strategy in the United States and other countries. At present, there is little research on the phenomenon of "food desert" in China. This study takes Shanghai as the research area and proposes a multiscale analysis method using a linear tessellation model that splits the street network into homogeneous linear units.

Demographic Characteristics and Relational Coordination in ICU Teams: Implications for Building Diverse and Effective Healthcare Collaboration.

Objective: To determine if professional roles and demographic characteristics predict relational coordination (RC) among healthcare professionals in the ICU.

Background: Race, age, and sex diversity are increasing in the medical and nursing workforce, raising questions regarding how well healthcare professionals are collaborating. RC is a validated model for coordinating interdependent work among healthcare professionals.

N-Glycosylation modulators for targeted manipulation of glycosylation for monoclonal antibodies.

Monoclonal antibodies are extensively used as biotherapeutics for treatment of a variety of diseases. Glycosylation of therapeutic antibodies is considered a critical quality attribute as it influences the effector function, circulatory half-life, immunogenicity, and eventually efficacy and patient safety. During upstream process development, media components play a significant role in determining the glycosylation profile.

Conventional and genetic association between migraine and stroke with druggable genome-wide Mendelian randomization.

The genetic relationship between migraine and stroke remains underexplored, particularly in the context of druggable targets. Previous studies have been limited by small sample sizes and a lack of focus on genetic-targeted therapies for these conditions. We analyzed the association and causality between migraine and stroke using multivariable logistic regression in the UK Biobank cohort and Mendelian randomization (MR) analyses based on genome-wide association study (GWAS) data.

Associations Between Coparenting Quality, the Home Food Environment, and Child's Body Mass Index.

Although positive coparenting, or how parents relate during childrearing, is known to support children's socioemotional development, the role of coparenting in supporting children's healthy eating and growth is poorly understood. This study examined associations between coparenting quality, the home food environment, and young children's body mass index (BMI). Cross-sectional data were obtained from 290 mothers and their 3-year-old children who participated in the Sprout study.

Surgical Repair of Double Outlet Right Ventricle Infants Guided by Three Dimensional-Computed Tomography Cardiac Modeling and Printing.

Background: Double outlet right ventricle (DORV) is a challenging congenital cardiac lesion to surgically master. We utilize computed tomography-guided-three-dimensional (3D) modeling/printing and novel in-house software to delineate anatomical relationships providing operative insight into the surgical approach. Our intent is to highlight this and showcase our technology.

Case report: Surgical closure of a facial defect in an African wild dog () utilizing a transpositional skin flap.

Veterinary intervention in zoological species can be complicated by species-specific social dynamics. African wild dogs are a pack species and removal or separation of an individual may disrupt established pack hierarchy resulting in conspecific aggression. Therefore, medical interventions that optimize a quick return to health are ideal to minimize the duration of absence from the pack.

Preliminary evaluation of the FastCAP for users of the Nurotron cochlear implant.

Background: Electrically evoked compound action potential (ECAP) can be used to measure the auditory nerve's response to electrical stimulation in cochlear implant (CI) users. In the Nurotron CI system, extracting the ECAP waveform from the stimulus artifact is time-consuming.

Method: We developed a new paradigm ("FastCAP") for use with Nurotron CI devices.

Do Land Use Plans Affirmatively Further Fair Housing?: Measuring Progress.

Problem Research Strategy And Findings: The 1968 Fair Housing Act required local government recipients of federal money to take meaningful actions to affirmatively further fair housing (AFFH). Current fair housing analysis requirements are copious but do not request an assessment of how land use policies affect the potential for neighborhood integration. A recent California law requires local governments to include AFFH analysis in existing planning processes, and state guidelines encourage the measurement of the spatial distribution of planned sites for low-income housing with respect to opportunity.

The influence of contemporary and emerging factors on blood lead concentrations among young males in conflict with the law: a case study from a middle-income country.

Introduction: Scientific evidence shows that contemporary and emerging factors contribute to high blood lead concentrations in different populations. The study aimed to determine blood lead concentrations and risk factors associated with high blood lead concentrations among young males in conflict with the law.

Methods: A cross-sectional analytical study was conducted among 192 conveniently selected participants from two youth secure (correctional) facilities in Gauteng Province, South Africa.

Pre-validation of a novel reconstructed skin equivalent model for skin irritation and nanoparticle risk assessment.

In alignment with the global movement toward reducing animal testing, several reconstructed human epidermis (RHE) models have been created for conducting skin irritation tests. These models have undergone development, verification, validation, and integration into OECD TG 439. Our team has introduced a novel in-house RHE named GB-RHE, and we adhere to OECD TG 439 to pre-validate the model and test its potential employment for nanoparticle irritation studies.

Advancements and challenges of onboard carbon capture and storage technologies for the maritime industry: a comprehensive review.

In response to the growing demand of reducing greenhouse gas (GHG) emissions within maritime sector, Onboard Carbon Capture and Storage (OCCS) technologies provide as key solutions for tackling carbon dioxide (CO) emissions from ships. This review paper offers a comprehensive overview of recent developments, challenges, and prospects of Carbon Capture and Storage (CCS) technologies considering specifically for onboard ship applications. Various Carbon Capture (CC) methods, ranging from post-combustion and pre-combustion capture to oxy-fuel combustion, are critically analysed concerning their operating principles, advantages, disadvantages and applicability in the maritime context.

In functionally aligned total knee arthroplasty, femoral component rotation follows the transepicondylar axis to achieve flexion balance.

Purpose: In functionally aligned (FA) total knee arthroplasty (TKA), femoral component rotation (FCR) is personalised to optimise flexion gap balance. As axial malalignment has been attributed to patellofemoral complications, this study assessed FA FCR in relation to the surgical transepicondylar axis (TEA) and early implant survivorship.

Methods: We analysed 446 robotic-assisted primary TKAs in 393 patients using FA with preresection gap balancing.

Evaluation of the recombinant protein -TSP-2 for the serological diagnosis of imported urogenital schistosomiasis and comparison with commercially available tests.

Different agencies have emphasized the need to evaluate current serological methods for screening patients with suspected urogenital schistosomiasis. However, there is still a lack of evidence regarding the most appropriate methods for this purpose. Here we assessed the diagnostic efficacy of a newly developed serological technique that utilizes the recombinant protein -TSP-2, applied to the urine and serum of migrants suspected of having urogenital schistosomiasis.

Factors Associated with the Patient Safety Activities among Home-Visit Caregiver: A Cross-Sectional Study.

Background: Home-visit care should prioritize patient safety and promote positive safety awareness to maintain caregivers' commitment to providing safe care. This descriptive study aims to examine the relationship between home-visit caregivers' knowledge, attitudes, awareness of patient safety, and safety-related activities.

Methods: The participants were 210 adult home-visit caregivers, aged 20 years or older, with more than six months of experience working at six long-term care centers in D Metropolitan City.

What are the training and support needs for homelessness hostel staff supporting older residents with memory and cognitive problems? A qualitative study.

Background: An increasing number of older people are experiencing homelessness and memory problems, many of whom are supported in temporary hostel accommodation. This can be a challenge for hostel staff who may not have adequate training and support but who often support those with significant memory impairment in their day-to-day work. The study aimed to investigate the training and support that hostel staff require to meet the needs of older hostel residents experiencing memory and cognitive problems, and thus enhance hostel resident quality of life and well-being, considering what additional knowledge, skills, and support hostel staff need to achieve this.

Prenatal maternal stress: triangulating evidence for intrauterine exposure effects on birth and early childhood outcomes across multiple approaches.

Background: Maternal stress during pregnancy may impact offspring development via changes in the intrauterine environment. However, genetic and environmental factors shared between mothers and children might skew our understanding of this pathway. This study assesses whether prenatal maternal stress has causal links to offspring outcomes: birthweight, gestational age, or emotional and behavioral difficulties, triangulating across methods that account for various measured and unmeasured confounders.

Home Healthcare Medication Safety risks among older adults with chronic diseases: a qualitative study.

Background: Older adults receiving home care often face significant safety risks related to medication management due to their chronic diseases and complex health needs. Despite the increasing reliance on home healthcare services, the specific factors contributing to medication safety risks in this demographic remain inadequately explored.

Objective/aim: This study aims to explore the key factors involved in medication safety risks among older adults with chronic diseases receiving home healthcare in Iran.

A novel ready-to-use loop-mediated isothermal amplification (LAMP) method for detection of Burkholderia mallei and B. pseudomallei.

Background: Glanders and melioidosis are contagious zoonotic diseases caused by Burkholderia mallei and B. pseudomallei, respectively. Bacterial isolation and polymerase chain reaction (PCR) have been used to detect these bacteria in animals suspected of infection; however, both methods require skilled experimental techniques and expensive equipment.

Stevioside mitigates metabolic dysregulation in offspring induced by maternal high-fat diet: the role of gut microbiota-driven thermogenesis.

Maternal obesity poses a significant threat to the metabolic profiles of offspring. Microorganisms acquired from the mother early in life critically affect the host's metabolic functions. Natural non-nutritive sweeteners, particularly stevioside (STV), play a crucial role in reducing obesity and affecting gut microbiota composition.

MythicVision: a deep learning powered mobile application for understanding Indian mythological deities using weight centric decision approach.

Indian mythology is a treasure trove of divine tales, yet a gap in understanding still exists between foreign tourists and the rich cultural heritage of Indian deities. To address the problem, this paper presents a deep learning-driven mobile application named "MythicVision" designed to help foreign tourists better understand India's rich cultural heritage by recognizing and interpreting images of Indian mythological deities. At first, four state-of-the-art deep models have been trained and evaluated on a custom in-house dataset consists of 10,970 images of various Indian deities sourced from both natural scene and web images.

Evaluation of hesperidin as a potential larvicide against Culex pipiens with computational prediction of its mode of action via molecular docking.

Hesperidin, a natural flavanone glycoside predominantly found in citrus fruits, has gained attention for its wide-ranging biological activities, including potential insecticidal properties. Culex pipiens, commonly known as the northern house mosquito, is a major vector of several human pathogens, such as the West Nile virus and filariasis, making it a key target in the fight against vector-borne diseases. In this study, we evaluated the larvicidal activity of Hesperidin against Culex pipiens larvae, assessing its potential as an alternative to chemical insecticides.