5 results match your criteria: "Hotchkiss Brain Institute Calgary[Affiliation]"
Safety and Efficacy of Intravenous Thrombolysis by Infarct Type in Patients with No Visible Occlusion: A Secondary Analysis of the AcT Trial.
J Am Heart Assoc
January 2025
Division of Neurology, Rady Faculty of Health Sciences University of Manitoba Winnipeg MB Canada.
Background: About 25% of patients with acute ischemic stroke have lacunar infarct on follow-up imaging. In this secondary analysis from the AcT (Alteplase Compared With Tenecteplase) trial, we assessed if there is variation in safety or efficacy of intravenous thrombolysis by infarct type in patients with no visible occlusion. We also determined if this effect differed between tenecteplase and alteplase.
View Article and Find Full Text PDFThe influence of personality in persons with MS.
Mult Scler Relat Disord
January 2024
Lawson Health Research Institute, London, ON, Canada; Department of Clinical Neurological Sciences, Western University, London, ON, Canada; Department of Clinical Neurological Sciences, University of Calgary, Hotchkiss Brain Institute Calgary, AB, Canada. Electronic address:
Article Synopsis
- Understanding how personality traits and demographics affect outcomes like job performance and mental health in people with Multiple Sclerosis (MS) can help improve treatment and support strategies.
- Researchers studied 384 individuals with MS to see how factors like age, education, and personality traits, specifically conscientiousness and neuroticism, influenced various outcomes.
- Results indicated that younger age and higher education led to better outcomes, while higher neuroticism was linked to increased anxiety and depression, and women experienced more anxiety than men.
- Future interventions should target individuals with high neuroticism and consider other factors such as social support and coping strategies to enhance understanding and management of MS.
Objectives: While co-morbid depression is associated with poor functional outcome among patients with schizophrenia, whether depression similarly predicts poorer outcomes in individuals at clinical high-risk for psychosis (CHR-P) is not clear. The present study aimed to examine depressive symptoms in relation to long-term global functional outcomes in the North American Prodrome Longitudinal Study cohort (NAPLS2).
Methods: CHR individuals were evaluated clinically at baseline and at 12- and 24-month follow-ups for depressive and prodromal symptom severity as well as general functioning.
Background Cerebral amyloid angiopathy (CAA) causes cognitive decline, but it is not known whether it is associated with neuropsychiatric symptoms (NPS). Methods and Results Participants with CAA, mild cognitive impairment, mild dementia due to Alzheimer's disease, and normal cognition were recruited from stroke and dementia clinics and community advertising. NPS were captured using the Neuropsychiatric Inventory Questionnaire short form.
View Article and Find Full Text PDFHot flashes are associated with altered brain function during a memory task.
Menopause
March 2020
University of Oklahoma Department of Obstetrics and Gynecology, Oklahoma City, Oklahoma.
Objective: Vasomotor symptoms (VMS) are associated with decreased memory performance and alterations in brain function. We conducted a preliminary examination of VMS and patterns of brain activity during a verbal memory task to provide insights into the VMS-related brain mechanisms that can contribute to memory problems in midlife women.
Methods: Fourteen postmenopausal women (mean age 53.