Anti-hepatocellular carcinoma activities of novel hydrazone derivatives downregulation of interleukin-6.

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related morbidity worldwide. Sorafenib is a first-line drug for the treatment of HCC, however, it is reported to cause serious adverse effects and may lead to resistance in many patients. In this study, 20 hydrazone derivatives incorporating triazoles, pyrazolone, pyrrole, pyrrolidine, imidazoline, quinazoline, and oxadiazine moieties were designed, synthesized, and characterized.

Adsorption and separation of Cs(I) and Ba(II) from aqueous solution using zinc ferrite-humic acid nanocomposite.

Reclaimable adsorbents have an essential role in removing radionuclides from waste streams. Herein, zinc ferrite-humic acid ZFO/HA nanocomposite was synthesized for effective cesium and barium adsorption. The prepared ZFO/HA nanocomposite was analyzed using analytical techniques including XRD, FTIR, EDX, and SEM.

Assessment of POFA -Cementitious material as backfill barrier in DSRS borehole disposal: Ra confinement.

Disused Sealed Radioactive Sources (DSRS) borehole disposal is an innovative concept recommended by international atomic energy agency (IAEA) to improve the safety and security of the management end point for these sources. A green application of Palm Oil Fuel Ash (POFA) as a supplementary material for cementitious backfill barrier in DSRS borehole disposal facility is proposed. Samples with up to 50% POFA replacement complied with the mechanical and hydraulic performance requirements for backfill barriers in retrievable radioactive waste disposal facilities.

Analysis of total phenolic compounds in tea and fruits using diazotized aminobenzenes colorimetric spots.

The present work describes a novel and rapid approach for evaluating total phenolic compounds (TPCs) in tea and fruits using colorimetric spots and the digital image-based (DIB) method. Colorimetric spots were formed by reacting diazotized aminobenzenes namely sulfanilic acid, sulfanilamide, or aniline with TPCs in the extract to form an azo dye. The limit of detection (LOD) was 6.

Assessment of Cyanex 301 impregnated resin for its potential use to remove cobalt from aqueous solutions.

The feasibility of using Cyanex 301 impregnated onto biopolymer resin for removing cobalt from radioactive waste streams is investigated. The emulsion compositions for resin preparation were optimized to ensure compliance with nuclear grade resin specifications on particle size distribution and chemical stabilities using multi-variant analysis. The enhanced chemical stabilities of the resins in different solutions are attributed to the interaction between Cyanex 301 and the emulsifier with alginate via a reaction with the glycosidic bond.

Synthesis of magnetic iron oxide nanoparticles using pulp and seed aqueous extract of Citrullus colocynth and evaluation of their antimicrobial activity.

Objectives: Citrullus colocynth (CTC) is a wild medicinal plant with proven antimicrobial activity. The aim of this study is to investigate the use of its aqueous extract in producing magnetic iron oxide nanoparticles (MNPs) with improved antimicrobial activity. The cold and hot aqueous extract of seed and pulp parts of CTC, respectively, were used to produce MNPs.

An Assessment of Initial Leaching Characteristics of Alkali-Borosilicate Glasses for Nuclear Waste Immobilization.

Initial leaching characteristics of simulated nuclear waste immobilized in three alkali- borosilicate glasses (ABS-waste) were studied. The effects of matrix composition on the containment performance and degradation resistance measures were evaluated. Normalized release rates are in conformance with data reported in the literature.

Evaluation of the Activity of Gamma-Emitting Natural Radionuclides in Seafood and Estimation of the Annual Effective Dose for Different Age Groups in KSA.

Twenty-six brands of canned tuna and sardines imported from several countries in Southeast Asia to consume in the KSA. All samples were prepared and analyzed by using a High Pure Germanium Detector of 40% efficiency. Natural radionuclides 40K, 238U (226Ra) and 232Th(228Ra) series were observed with a varying range in all analyzed samples.

Tc-zolmitriptan: radiolabeling, molecular modeling, biodistribution and gamma scintigraphy as a hopeful radiopharmaceutical for lung nuclear imaging.

Lung imaging radiopharmaceuticals are helpful agents for measuring pulmonary blood flow and allow detection of pulmonary embolism and lung cancer. The goal of this study was to develop a novel potential radiopharmaceutical for lung imaging. Zolmitriptan (a selective serotonin receptor agonist) was successfully labeled with Tc via direct labeling method under reductive conditions studying different factors affecting the labeling efficiency.

Chemical studies on polyaniline titanotungstate and its uses to reduction cesium from solutions and polluted milk.

Polyaniline titanotungstate (PATiW) was synthesized by the sol-gel method. Adsorption isotherm studies of Cs(+) from aqueous solution are described. Elemental Composition, chemical solubility, ion-exchange capacity (IEC) and pH-titration curve are studied.

Mobility of radionuclides in soil/groundwater system: comparing the influence of EDTA and four of its degradation products.

The adsorption behavior of 241Am, 60Co, 137Cs and 85Sr in the presence and absence of chelating ligands (ethylenediaminetetraacetic acid, ethylenediaminediacetic acid, hydroxyethyliminodiacetic acid, iminodiaceiticacid and methyliminodiacetic acid) was investigated. Sorption affinity in the absence of chelating ligands followed: Am(III)>Co(II)>Cs(I)>Sr(II). The presence of chelating ligands generally had little effect on sorption of 85Sr and 137Cs with Kd values 110 and 690 mL g(-1), respectively.

Extraction and separation of Co(II) and Ni(II) from acidic sulfate solutions using Aliquat 336.

Extraction and separation of Co(II) and Ni(II) from acidic sulfate solutions by solvent extraction technique were studied using different forms of Aliquat 336 diluted with kerosene. The extraction percent of each metal ion was found to increase with increasing pH and extractant concentration. Co(II) was preferentially extracted by different forms of Aliquat 336 over Ni(II) under the same extraction conditions.

Kinetics of acid leaching of ilmenite decomposed by KOH Part 2. Leaching by H2SO4 and C2H2O4.

A kinetic study of the leaching of ilmenite paste (resulting from ilmenite treatment by KOH) by sulfuric and oxalic acids has been investigated. The effects of the reaction agitation speed, ilmenite paste particle size, acid concentration, acid/paste mass ratio and temperature on titanium recovery percent from the KOH decomposed ilmenite are reported. The leaching rates are significantly influenced by the reaction temperature and acid concentration.

Sorption potential of impregnated charcoal for removal of heavy metals from phosphoric acid.

The viability of some heavy ions removal from phosphoric acid solution by means of impregnated charcoal with triphenylphosphine sulphide extractant has been demonstrated in this work. Factors affecting removal of Cu(2+), Cd(2+), Zn(2+)and Pb(2+) include initial concentration of ions, volume of the aqueous solution to weight of adsorbent ratio (V/m), concentration of the extractant loaded onto charcoal and temperature. The removal percent of these ions is increased by decreasing values of V/m ratio and increasing temperature for all ions.

Two-step method for preparation of NaA-X zeolite blend from fly ash for removal of cesium ions.

Pure zeolites can be synthesized from silica extracts obtained from fly ash by alkaline leaching. The extraction potential of industrial by-product fly ash was investigated under repeated fusion process conditions. The amount of extracted silica was 131.

Removal of lanthanum and gadolinium from nitrate medium using Aliquat-336 impregnated onto Amberlite XAD-4.

Aliquat-336 in benzene was supported on Amberlite XAD-4 crosslinked polystyrene resin. The use of XAD-4 impregnated with Aliquat-336 resin for removal of lanthanum(III) and gadolinium(III) from nitrate medium was carried out using batch technique. Various parameters affecting the uptake of these metal ions such as contact time, metal ion concentrations, V/m and pH value were separately studied.

Evaluation of zeolite A for the sorptive removal of Cs+ and Sr2+ ions from aqueous solutions using batch and fixed bed column operations.

Zeolite A was chemically synthesized and evaluated, as inorganic ion exchange material, for the removal of cesium and strontium ions from aqueous solutions in both batch and fixed bed column operations. Batch experiments were carried out as a function of pH, initial ion concentration and temperature. Simple kinetic and thermodynamic models have been applied to the rate and isotherm sorption data and the relevant kinetic and thermodynamic parameters were determined from the graphical presentation of these models.

Development of a long-term stable organic membrane-based thin-film microsensor using new-type substrate surface treatment.

A novel long lifetime organic membrane-based thin-film Cu(II) microsensor has been elaborated. The advantages of the suggested microsensor include: excellent stability, long lifetime, and reasonable good selectivity. The significant improvements of the lifetime (>4 months) of the organic membrane-based thin-film microsensors have been realized for the first time using new-type electrodeposition treatment of the solid-state substrate surface in combination with a new nebulization method for applying the organic membrane coating mixture on the thin-film gold substrate.

Simultaneous measurement of (226)Ra and (228)Ra in natural water by liquid scintillation counting.

Several types of bottled drinking water originating from three different areas in Egypt are studied through measurement of radium activity, assessment of related annual dose for adults and finally to define the role of water quality on radium levels. The mean levels of (226)Ra activity range from 0.44 to 0.

Modeling the long-term leaching behavior of (137)Cs, (60)Co, and (152,154)Eu radionuclides from cement-clay matrices.

Leaching characteristics of some radionuclides that are commonly encountered in radioactive waste streams from immobilized waste matrices in different cement-clay grouts have been assessed to investigate the influence of the clay additives on the leaching behavior of the solid waste matrices. The International Atomic Energy's Agency (IAEA) standard leach method has been employed to study the leach pattern of (137)Cs, (60)Co, and (152,154)Eu radionuclides immobilized in ordinary Portland cement (OPC), OPC-bentonite, and OPC-red clay grouts. The examination of the leaching data revealed that adding clays to OPC reduces the leach pattern as OPC-bentonite View Article and Find Full Text PDF

Studies on the sorption of praseodymium (III), holmium (III) and cobalt (II) from nitrate medium using TVEX-PHOR resin.

The use of TVEX-PHOR resin for the sorption of praseodymium (III), holmium (III) and cobalt (II) from nitrate medium was carried out using batch and column techniques. Various parameters affecting the uptake of these metal ions such as v/m ratio, pH and the metal ion concentration were separately studied. Effect of temperature on the equilibrium distribution values has been studied to evaluate the changes in standard thermodynamic quantities.

Modeling batch kinetics and thermodynamics of zinc and cadmium ions removal from waste solutions using synthetic zeolite A.

The sorptive removal of zinc and cadmium ions from aqueous solutions using synthetic zeolite A was investigated. Experiments were carried out as a function of solute concentration and temperature (298-333 K). Several kinetic models were used to test the experimental rate data and to examine the controlling mechanism of the sorption process.