Nebulizable colloidal nanoparticles co-encapsulating a COX-2 inhibitor and a herbal compound for treatment of lung cancer.

A challenging disease such as lung cancer requires the combination of different modalities to achieve beneficial therapeutic outcomes. In this work, PLGA nanoparticles were chosen as colloidal carrier for two drugs with reported anti-lung cancer activity: naringin and celecoxib. PLGA nanoparticles were prepared and characterized for their particle size, zeta potential, entrapment efficiency, in vitro release, stability, morphology, cytotoxicity, as well as aerosolization and nebulization behaviors.

Valence stabilization of polyvalent ions during gamma irradiation of their aqueous solutions by sacrificial protection. III-Valence stabilization of Fe(II) ions by organic additives.

Valence stabilization of polyvalent ions in gamma irradiated aqueous solutions is sometimes necessary in some chemical operations. In previous publications, valence stabilization of some polyvalent ions in solution upon gamma irradiation was achieved by using inorganic additives capable of interacting with the oxidizing or reducing species formed during water radiolysis. The results showed that the nature and duration of valence stabilization of Fe(II) depend on the concentration of the inorganic additives used.

Preparation of (99m)tc-clomiphene citrate as a novel agent for breast cancer imaging.

The aim of this work was to develop a novel (99m)Tc-labelled derivative based on triphenylethylene for breast cancer imaging. (99m)Tc-Clomiphene was obtained with a radiochemical yield of 94.4% by adding (99m)Tc to 1.

Synthesis and characterization of magnetic hexacyanoferrate (II) polymeric nanocomposite for separation of cesium from radioactive waste solutions.

Nanocrystalline potassium zinc hexacyanoferrate loaded on nanoscale magnetite substrate was successfully synthesized for significantly enhanced removal of cesium from low-level radioactive wastes. A description was given for preparation and properties of these precursors. The physicochemical properties of these nanocomposites were determined using different techniques including Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), thermogravimetric analysis (TGA), scanning electron microscopy (SEM), and energy dispersive spectroscopy (EDS).

Preparation of 65Zn and 134Cs sealed sources based on commercial organic and synthesized inorganic sorbents for calibration purposes of gamma-detectors.

The sealed source of (65)Zn was prepared by using permutit as a commercial organic resin in an anion form, while in case of the (134)Cs, the sealed source was prepared by using the synthesized 12-molybdocerate(IV) gel as an inorganic exchanger in cation form. The batch technique was carried out for loading (65)Zn from 0.2 M HCl-60% acetone medium and for loading (134)Cs from 0.

Production of effective luteinizing hormone antisera by two immunization methods.

This paper addresses the production of effective luteinizing hormone antisera by two different immunization methods; the traditional and modified methods. The main difference between these two methods is in the immunization procedure. In the modified method, an additional injection of emulsion with complete Freund's adjuvant and only one booster are applied at the third and 28th day from the first injection, respectively.

Sorption behavior of Zn(II) ions on synthesized hydroxyapatites.

Calcium hydroxyapatite (CaHAP) and barium hydroxyapatite (BaHAP) have been prepared by a wet method from aqueous solutions with cation/P molar ratio of 1.67. The prepared particles were characterized using XRD, IR, TG-DTA and BET-N(2) adsorption measurements.

Preparation and evaluation of cerium(IV) tungstate powder as inorganic exchanger in sorption of cobalt and europium ions from aqueous solutions.

Cerium(IV) tungstate powder was chemically synthesized and exploited as adsorbent material for the decontamination study of cobalt and europium ions from radioactive waste solutions under simulated conditions using batch technique. The influences of pH, particle size and temperature have been reported. The uptake of europium was found to be slightly greater than that of cobalt and the apparent sorption capacity increases with increase in temperature.

Immobilization of cesium and strontium radionuclides in zeolite-cement blends.

Zeolites are preferred ion exchange materials for the removal of radioisotopes from aqueous nuclear wastes because of their selectivity, radiation and temperature stability, and good compatibility with the cement matrix. Loaded materials, which are not regenerated, are preferably embedded in a solid matrix prior to ultimate storage in a repository. The aim of the present study is to investigate the possibility of solidifying exhausted synthetic zeolite A, loaded with (137)Cs and/or (90)Sr radionuclides, in Ordinary Portland Cement (OPC).

Separation and purification of 131I from tellurium material using ion exchange for preparing tetra-butyl ammonium iodide (131I).

A comparison of the distribution coefficients (Kd) of tellurium and iodine-131 (131I) between hydrochloric acid of various concentrations (without and in presence of 0.1 M thiourea) and the cation exchange resin (Dowex50WX8) was studied. The Kd of tellurium and 131I at different concentrations of thiourea in 0.

Direct separation of 67Ga citrate from zinc and copper target materials by anion exchange.

The separation of 67Ga from zinc and copper target materials using an anion-exchanger (Dowex21K) and 0.1M citrate buffer at pH 6 is described. The gallium-67 was separated in citrate solution and can be directly used for medical applications.

A new lead(II)-selective PVC-coated graphite rod electrode based on a Schiff base complex.

A new lead(II)-selective electrode has been developed based on bis(acetylacetone)-p-phenylenediamine-lead(II) [LPb(NO3)2]H2O complex ionophore as a sensing material, dioctylphthalate (DOP) as a solvent mediator and PVC as a matrix. This electrode exhibits a linear Nernstian response over the concentration range of 1 x 10(-5)-1 x 10(-1) mol l(-1) of Pb(II) cation, with a cationic calibration slope of 30.0 +/- 0.