2 results match your criteria: "Hospitals of the University of the Saarland[Affiliation]"

Treatment of epistaxis in hereditary hemorrhagic telangiectasia with tranexamic acid - a double-blind placebo-controlled cross-over phase IIIB study.

Thromb Res

September 2014

Institute of Medical Biostatistics, Epidemiology and Informatics, Division Medical Biometry, University Medical Center, Johannes Gutenberg University, Mainz, Germany; Formerly of: Institute of Medical Biostatistics, Epidemiology and Informatics, University of the Saarland, Homburg/Saar, Germany.

Introduction: Epistaxis is the most frequent manifestation in hereditary hemorrhagic telangiectasia, in which no optimal treatment exists. It can lead to severe anemia and reduced quality of life. Positive effects of tranexamic acid, an antifibrinolytic drug, have been reported on epistaxis related to this disorder.

View Article and Find Full Text PDF

Objective: To assess and differentiate the health-related quality of life (HR-QoL) in patients with hereditary hemorrhagic telangiectasia (HHT).

Study Design And Setting: A prospective, open, cross-sectional questionnaire-based study (including the Short Form-36 Health Survey [SF-36]) performed by a tertiary care center.

Results: A total of 77 patients (36 females) were included.

View Article and Find Full Text PDF