Improvement of self-administration experience with a new injection device: Real-life experience with risankizumab in patients with psoriasis.

Background: Trypanophobia or "needle phobia" represents a potential hindrance to the effective management of chronic diseases whenever an injectable therapy might be required, especially in case of frequent administrations. Psoriasis, a chronic dermatologic disease, can be effectively treated with biologic drugs administered subcutaneously. Thankfully, anti-IL-23 drugs require few administrations per year and are available in prefilled pens that hide the needle, thus representing a convenient option in patients with trypanophobia.

Do prostaglandin analogs affect eyelid position and motility?

Purpose: The authors aim at investigating the possible clinical effects of topical Prostaglandin Analogs on eyelid position and motility with this single masked protocol in a cross-sectional study.

Methods: A group (group A) of 182 patients on treatment for glaucoma with prostaglandin analogs (latanoprost, travoprost, and bimatoprost) and a group of 191 age-matched normal controls (group B) were enrolled in the study. Group A was subdivided into 3 subgroups according to the prostaglandin analogs used by the patients.

IgA nephropathy associated with Takayasu's arteritis: report of a case and review of the literature.

We report the case of a patient with Takayasu's arteritis, nephrotic syndrome, and pANCA. The kidney biopsy specimen showed the classic features of IgA nephropathy. The course of this patient supports the view that the glomerular and vasculitic involvements of Takayasu's arteritis may result from a common immunologic mechanism, and cases with urinary abnormalities should be carefully followed for the possible coexistence of glomerulonephritis.