5 results match your criteria: "Hospital of Affiliated Changchun University of Chinese Medicine[Affiliation]"

Low toxicity ginsenoside Rg1-carbon nanodots as a potential therapeutic agent for human non-small cell lung cancer.

Colloids Surf B Biointerfaces

February 2025

Jilin Ginseng Academy, Institute of Traditional Chinese Medicine, Hospital of Affiliated Changchun University of Chinese Medicine, Changchun University of Chinese Medicine, Changchun 130117, PR China; Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, Queensland 4072, Australia. Electronic address:

Article Synopsis
  • Researchers synthesized Rg1 carbon nanodots from ginsenoside Rg1 using a one-step hydrothermal method, creating particles that are water-soluble and biocompatible.
  • These nanodots effectively inhibited the growth, movement, and cell death mechanisms in non-small cell lung cancer A549 cells by affecting cellular pathways and protein expression related to apoptosis.
  • In animal tests, the Rg1 carbon nanodots showed much greater tumor growth inhibition compared to standard chemotherapy drugs, with minimal toxicity, indicating their potential as a new treatment for lung cancer.
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Background: To systematically evaluate the clinical efficacy of using the method of activating blood circulation and removing blood stasis in the treatment of microvascular angina (MVA) based on the meta-analysis method.

Methods: A comprehensive search of randomized controlled trials on the treatment of MVA using the method of activating blood circulation and removing blood stasis in Chinese and English databases such as China National Knowledge Infrastructure Database, Wanfang Data Knowledge Service Platform, Vipshop Journal Resource Integration Service Platform, PubMed, Cochrane Library, Embase, Web of Science, and CBM was conducted, and the search time limit was from the establishment of each database to February 2023. All retrieved literature was screened, and data extracted according to the specified inclusion and exclusion criteria, and data analysis was completed using Revman 5.

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Background: With the advantages of miniature damage and optimal effectiveness, percutaneous coronary intervention (PCI) has been performed in a large number of coronary artery disease patients. However, recent studies have indicated a higher incidence of depression on post-PCI patients. Acupuncture therapy is effective for depression.

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A Novel Conductive Antibacterial Nanocomposite Hydrogel Dressing for Healing of Severely Infected Wounds.

Front Chem

November 2021

State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Chinese-Japan Union Hospital of Jilin University, Jilin University, Changchun, China.

Wound infections are serious medical complications that can endanger human health. Latest researches show that conductive composite materials may make endogenous/exogenous electrical stimulation more effective, guide/comb cell migration to the wound, and subsequently promote wound healing. To accelerate infected wound healing, a novel medical silver nanoparticle-doped conductive polymer-based hydrogel system (Ag NPs/CPH) dressing with good conductivity, biocompatibility, and mechanical and antibacterial properties was fabricated.

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In-stent restenosis (ISR) is the main factor affecting the outcome of percutaneous coronary intervention (PCI), and its main pathological feature is neointimal hyperplasia. Huotan Jiedu Tongluo decoction (HTJDTLD) is an effective traditional Chinese medicine (TCM) prescription for the treatment of vascular stenosis diseases. However, the precise anti-ISR mechanism of HTJDTLD remains unclear.

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