3 results match your criteria: "Hospital for Special Surgery and Mount Sinai Hospital[Affiliation]"

Article Synopsis
  • The study aimed to understand nonarticular pain (NAP) in patients newly diagnosed with rheumatoid arthritis (RA), tracking its changes during the first year of treatment and linking it with active inflammation and remission outcomes.
  • More than half of the participants (392, mostly female, average age of 56) experienced NAP, with the majority reporting regional pain, which often persisted or worsened over time.
  • The results indicated that both regional and widespread NAP were negatively associated with achieving remission, suggesting that addressing NAP is crucial in managing early RA.
View Article and Find Full Text PDF

Background/objective: In patients with rheumatoid arthritis (RA), high tender-swollen joint differences (TSJDs) have been associated with worse outcomes. A better understanding of the phenotype and impact of high TSJD on patient-reported outcomes (PROs) in early RA may lead to earlier personalized treatment targeting domains that are important to patients today. Our objectives were to evaluate the impact of TSJD on updated PROs in patients with early RA over 1 year and to determine differences in associations by joint size.

View Article and Find Full Text PDF

Objective: Patients with early rheumatoid arthritis (RA) may present with more tender than swollen joints, which can persist. Elevated tender-swollen joint difference (TSJD) is often challenging, because there may be multiple causes and it may contribute to overestimating disease activity. Little is known about the phenotype and impact of TSJDs on patient function.

View Article and Find Full Text PDF