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Alterations in Brain Network Organization in Adults With Obesity as Compared With Healthy-Weight Individuals and Seniors.
Psychosom Med
September 2021
From the Department of Psychiatry (González), University of Vermont College of Medicine, Burlington; Departament de Psicologia Clínica i Psicobiologia (Jurado, Caldú, Prats-Soteras, García-García) and Institut de Neurociències (Baggio, Jurado, Segura, Caldú, Prats-Soteras, García-García), Universitat de Barcelona; Institut de Recerca Sant Joan de Dèu (Ottino-González, Jurado, Caldú, Prats-Soteras, García-García), Hospital Sant Joan de Dèu; Departament de Medicina (Baggio, Segura), Universitat de Barcelona, Barcelona; Montreal Neurological Institute (Dadar, Dagher), McGill University, Montreal, Canada; Unitat d'Endocrinologia, Hospital de Terrassa (Miró, Sánchez-Garre), Consorci Sanitari de Terrassa; and CAP Terrassa Nord (Tor, Sender-Palacios), Unitat de Neuropsicologia, Hospital de Terrassa (Garolera), and Brain, Cognition and Behaviour Research Group (Garolera), Consorci Sanitari de Terrassa, Spain.
Article Synopsis
- The study aimed to investigate whether adults with obesity show signs of premature brain aging compared to healthy-weight individuals and seniors.
- Participants included 30 adults with obesity, 33 healthy-weight controls, and 30 seniors, all analyzed using brain imaging techniques.
- Results indicated that obese participants had a higher clustering coefficient and lower global degree than seniors, suggesting that obesity may not be linked to premature brain aging as previously thought, and might instead reflect different network functioning relevant to aging.