2,423 results match your criteria: "Hospital de Pediatría del Centro Médico Nacional Siglo XXI[Affiliation]"
Food Funct
December 2024
Laboratorio de Nutrición Molecular, Unidad de Investigación Médica en Nutrición, Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de México (CDMX), Mexico.
This research aimed to analyze the percentage of short-chain fatty acids (SCFAs) in human milk (HM) and newborn feces and to explore potential associations with factors such as maternal nutrition, age, biological sex, delivery mode, diet, and the type of HM. Gas chromatography was used to measure the percentage of SCFAs in colostrum ( = 23), transitional HM ( = 23), and mature HM ( = 92) and feces of newborn ( = 36) at day 30 postpartum. Anthropometry was also evaluated in the mother and the infant.
View Article and Find Full Text PDFArch Med Res
December 2024
División de Excelencia Clínica, Instituto Mexicano del Seguro Social, Mexico City, Mexico.
Background: As the number of programs aimed at preventing fragility fractures and mitigating the phenomenon of cascade fractures is increasing worldwide, so it is necessary to evaluate the effectiveness of such programs to seek their feasible implementation at regional and global levels.
Aims: This paper aims to provide an overview focusing on the incidence of secondary fractures after the implementation of any type of fracture liaison service (FLS). To this end, a scoping review was conducted focusing on the identification of clinical evidence reported in systematic reviews of the medical literature in this area.
Nat Prod Res
December 2024
Unidad de Investigación Médica en Enfermedades Nefrológicas, Hospital de Especialidades "Dr. Bernardo Sepúlveda Gutiérrez", Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Cuauhtémoc, Mexico.
Three iridoid glycosides (mussaenoside, geniposide, and 5-hydroxy-8-epi-deoxyloganin) along with mannitol and acteoside, were isolated from , an endemic plant species of Mexico that currently belongs to the Orobanchaceae family. There is no information about the chemical composition of this species, consequently, the present work focuses on the chemical study of the flowers and leaves of , which were collected in two batches in Mexico, identifying the main components of each batch. The chemical structures were completely established by spectroscopic methods.
View Article and Find Full Text PDFN Engl J Med
December 2024
From Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York (K.L.J.); University Hospitals Leuven, Leuven, Belgium (P.N.); Hospital María Curie, Buenos Aires (M.L.C.); Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea (S.-B.K.); National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan (E.T.); Institut Jules Bordet, Hôpital Universitaire de Bruxelles, Brussels (P.A.); Vall d'Hebron University Hospital, Vall d'Hebron Institute of Oncology, Barcelona (C.S.); Baylor University Medical Center, Texas Oncology, U.S. Oncology, Dallas (J.O.); the Breast Center, Department of Obstetrics and Gynecology and Comprehensive Cancer Center Munich, Ludwig Maximilians University Munich University Hospital, Munich, Germany (N.H.); the University of North Carolina at Chapel Hill, Chapel Hill (L.A.C.); the University of Milan, Milan (G.C.); the European Institute of Oncology, IRCCS, Milan (G.C.); Hospital Arnau de Vilanova, Valencia, Spain (A.L.-C.); Garvan Institute of Medical Research and University of New South Wales, Sydney (E.L.); Hospital de Oncología, Centro Médico Nacional Siglo XXI, Mexico City (M.L.G.T.); Yonsei University College of Medicine, Seoul, South Korea (J.S.); the Mastology Department, Women's Health Hospital, São Paulo (A.M.); Harbin Medical University Cancer Hospital, Harbin, China (Q.Z.); National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei (C.-S.H.); the Division of Breast Surgery, Department of Surgery, Taichung Veterans General Hospital, Taichung, Taiwan (C.-C.H.); Filios Alta Medicina, Monterrey, Mexico (J.L.M.R.); the Medical Oncology Department, Hospital Universitario Virgen del Rocío, Seville, Spain (M.R.B.); the Department of Breast Surgery, Chiba Cancer Center Hospital, Chiba, Japan (R.N.); Eli Lilly, Indianapolis (K.R.P., C.C.L., E.B., S.C., X.A.W., L.M.S.); and Institut Curie and University of Versailles Saint-Quentin-en-Yvelines-Paris-Saclay University, Paris (F.-C.B.).
Background: Imlunestrant is a next-generation, brain-penetrant, oral selective estrogen-receptor (ER) degrader that delivers continuous ER inhibition, even in cancers with mutations in the gene encoding ERα ().
Methods: In a phase 3, open-label trial, we enrolled patients with ER-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced breast cancer that recurred or progressed during or after aromatase inhibitor therapy, administered alone or with a cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitor. Patients were assigned in a 1:1:1 ratio to receive imlunestrant, standard endocrine monotherapy, or imlunestrant-abemaciclib.
Proc Natl Acad Sci U S A
December 2024
Institute of Virology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin 10117, Germany.
Hepatitis E virus (HEV; family ) infections cause >40,000 human deaths annually. Zoonotic infections predominantly originate from ungulates and occasionally from rats, highlighting the zoonotic potential of rodent-associated hepeviruses. We conducted host genomic data mining and uncovered two genetically divergent rodent-associated hepeviruses, and two bat-associated hepeviruses genetically related to known bat-associated strains.
View Article and Find Full Text PDFHeart Rhythm O2
November 2024
Unidad Médica de Alta Especialidad en Pediatría, Centro Médico Nacional de Occidente, Instituto Mexicano del Seguro Social, Guadalajara, México.
Pediatr Nephrol
December 2024
Unidad de Investigación en Salud en El Trabajo, Centro Médico Nacional "Siglo XXI", Instituto Mexicano Del Seguro Social (IMSS), Ciudad de Mexico, Mexico.
Background: Anthropogenic vanadium (V) emissions and exposure in the general population have recently increased. Experimental studies have shown that V is a nephrotoxic agent, but little is known about its effects on human kidney health. This work evaluated the association between urinary V concentrations with early kidney damage biomarkers and function in a pediatric population without any disease diagnosed.
View Article and Find Full Text PDFRev Alerg Mex
September 2024
Centro Médico Nacional La Raza; Centro Médico San Carlos, Tlaxcala, Tlaxcala, México.
Front Oncol
November 2024
Unidad de Educación e Investigación, Instituto Mexicano del Seguro Social, Mexico City, Mexico.
Gac Med Mex
November 2024
Unidad de Investigación Epidemiológica y en Servicios de Salud, Área Envejecimiento, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City.
Background: The most common traumatic injury among older individuals worldwide is hip fracture. Higher incidence after 70 years old and women (80-85%). Hospital discharges in Mexico have little evidence.
View Article and Find Full Text PDFRev Med Inst Mex Seguro Soc
September 2024
Instituto Mexicano del Seguro Social, Hospital General Regional No. 1 "Dr. Carlos Mac Gregor Sánchez Navarro", Departamento de Epidemiología. Ciudad de México, México.
Background: Acute hemorrhagic leukoencephalitis (AHLE) or Weston-Hurst syndrome is a rare and severe variant of acute disseminated encephalomyelitis (ADEM). It causes fulminant hemorrhagic demyelination of the central nervous system, and has high mortality and morbidity. Due to the increase in cases and to its high rate of mortality, we decided to make a series of cases and a review of the disease.
View Article and Find Full Text PDFRev Med Inst Mex Seguro Soc
September 2024
Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades "Dr. Bernardo Sepúlveda Gutiérrez", Servicio de Dermatología. Ciudad de México, México.
Through multidisciplinary research, translational medicine allows a comprehensive approach to diseases in order to provide patients with adequate treatment, whose aim is personalized and precision medicine. In this context, the Cellular Immunology Laboratory of the Immunochemistry Research Unit, and the Dermatology Service of the 21st Century National Medical Center's Specialties Hospital (Hospital de Especialidades del Centro Médico Nacional Siglo XXI) have achieved a partnership that aspires to provide better quality patient care. This objective is achieved by evaluating the inflammatory skin infiltrates in different pathologies to observe changes in local immunity related to the response to treatment, and with the disease progression distinguish between dermatological diseases, highlight the importance of comprehensive skin care, and make decisions about treatment choice.
View Article and Find Full Text PDFRev Med Inst Mex Seguro Soc
September 2024
Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades "Dr. Bernardo Sepúlveda Gutiérrez", Dirección Médica. Ciudad de México, México.
Rev Med Inst Mex Seguro Soc
September 2024
Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Pediatría, Laboratorio de Investigación en Gastro-Hepatología. Ciudad de México, México.
Background: Several alterations in thyroid function have been identified in patients with liver cirrhosis (LC).
Objective: To carry out a thyroid disease screening in adult patients with LC.
Material And Methods: A cross-sectional study.
Rev Med Inst Mex Seguro Soc
September 2024
Instituto Mexicano del Seguro Social, Unidad de Atención a la Salud del IMSS-Bienestar. Ciudad de México, México.
Rev Med Inst Mex Seguro Soc
September 2024
Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades "Dr. Bernardo Sepúlveda Gutiérrez", Departamento de Gastroenterología. Ciudad de México, México.
Background: SARS-CoV-2 infection began in Wuhan, China, in December 2019, where the first cases of pneumonia were described. The infection spread rapidly and was established as a pandemic by the World Health Organization (WHO) in February 2020. In Mexico, the first cases were in March 2020.
View Article and Find Full Text PDFRev Med Inst Mex Seguro Soc
September 2024
Instituto Politécnico Nacional, Escuela Superior de Medicina, Sección de Estudios de Posgrado e Investigación. Ciudad de México, México.
Background: Multiple cranial neuropathies (MCN) are the dysfunction of 2 or more cranial nerves, simultaneously or sequentially. The most common causes are tumors, followed by vascular and traumatic causes, central nervous system infections and Guillain-Barré syndrome and its variants.
Objective: To identify the radiological clinical profile of MCN in patients of a tertiary-care hospital.
Rev Med Inst Mex Seguro Soc
September 2024
Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades "Dr. Bernardo Sepúlveda Gutiérrez", Unidad de Trasplante de Médula Ósea. Ciudad de México, México.
Background: Allogeneic hematopoietic stem cell transplantation (HSCT) is a therapy that offers the potential to cure hematological malignancies. One limitation is that only 25% of patients will have an identical donor. The use of haploidentical donors allows 95% of patients to have a donor.
View Article and Find Full Text PDFRev Med Inst Mex Seguro Soc
September 2024
Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades "Dr. Bernardo Sepúlveda Gutiérrez", Servicio de Imagenología. Ciudad de México, México.
The objective of this letter to the editor is to make a reflection about the past, present and future of the Specialties Hospital "Dr. Bernardo Sepúlveda Gutiérrez" from the 21st Century National Medical Center, on the occasion of its 60th anniversary.
View Article and Find Full Text PDFRev Med Inst Mex Seguro Soc
September 2024
Instituto Mexicano del Seguro Social, Centro Médico Nacional Siglo XXI, Hospital de Especialidades "Dr. Bernardo Sepúlveda Gutiérrez", Dirección Médica. Ciudad de México, México.
21st Century National Medical Center's Specialties Hospital from the Instituto Nacional del Seguro Social (IMSS, Mexican Institute for Social Security) was inaugurated in 1963 and up until this day it maintains three fundamental pillars: care, teaching, and scientific research. The hospital has 429 hospital beds, 80 consultation rooms, 19 operating rooms, 30 medical specialties made up of more than 800 resident doctors, in addition to 8 research units. As a form of recognizing more than 60 years of history, our hospital presents a series of research articles on current topics.
View Article and Find Full Text PDFJ Clin Med
November 2024
Hospital de Especialidades del Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Ciudad de México 06720, Mexico.
: Persistent Postural-Perceptual Dizziness (PPPD) is a frequent diagnosis in patients with chronic dizziness, ineffective postural control, visual dependence, and emotional symptoms. : 53 patients with PPPD (25-84 years old) and 53 adults (29-84 years old) with no vestibular disease agreed to participate in this study. Assessments included: vestibular function tests (sinusoidal yaw rotation and vestibular-evoked myogenic potentials); accuracy and precision of Subjective Visual Vertical (SVV) estimation while static and during on-axis yaw rotation; static posturography with open/closed eyes and 30° neck extension, while standing on hard/soft surface; questionnaires on symptoms of unsteadiness, spatial anxiety, dizziness-related handicap, anxiety/depression, depersonalization/derealization, and perceived stress.
View Article and Find Full Text PDFMicroorganisms
November 2024
Departamento de Microbiología Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional (ENCB, IPN), Ciudad de México 11340, Mexico.
The general features of the shift to a dormant state in mycobacterial species include several phenotypic changes, reduced metabolic activities, and increased resistance to host and environmental stress conditions. In this study, we aimed to provide novel insights into the viability state and morphological changes in dormant that contribute to its long-term survival under starvation or hypoxia. To this end, we conducted assays to evaluate cell viability, morphological changes and gene expression.
View Article and Find Full Text PDFMicroorganisms
October 2024
Laboratorio de Nutrición Molecular, Unidad de Investigación Médica en Nutrición, Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Ciudad de México 06720, Mexico.
Genes (Basel)
October 2024
Facultad de Medicina, Universidad Nacional Autónoma de Mexico, Mexico City 04360, CP, Mexico.
Background: Dementia causes the loss of functional independence, resulting in a decrease in the quality of life of those who suffer from it.
Aims: This study aimed to investigate the interactions influencing susceptibility to the development of dementia through multifactor dimensionality reduction (MDR).
Methods: the study population was made up of 221 cases and 534 controls.
Int J Mol Sci
November 2024
Departamento de Inmunología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, ENCB-IPN, Mexico City 11350, Mexico.