Statins do not increase Markers of Cerebral Angiopathies in patients with Cardioembolic Stroke.

We investigated whether pre-treatment with statins is associated with surrogate markers of amyloid and hypertensive angiopathies in patients who need to start long-term oral anticoagulation therapy. A prospective multicenter study of patients naive for oral anticoagulants, who had an acute cardioembolic stroke. MRI was performed at admission to evaluate microbleeds, leukoaraiosis and superficial siderosis.

Human Immunodeficiency Virus/Hepatits C Virus Coinfection in Spain: Elimination Is Feasible, but the Burden of Residual Cirrhosis Will Be Significant.

Background: We assessed the prevalence of antibodies against hepatitis C virus (HCV-Abs) and active HCV infection in patients infected with human immunodeficiency virus (HIV) in Spain in 2016 and compared the results with those of similar studies performed in 2002, 2009, and 2015.

Methods: The study was performed in 43 centers during October-November 2016. The sample was estimated for an accuracy of 2% and selected by proportional allocation and simple random sampling.

PET-CT in presurgical lymph node staging in non-small cell lung cancer: the importance of false-negative and false-positive findings.

Objective: To assess the importance of false-negative and false-positive findings in computed tomography (CT) and F-FDG positron emission tomography (PET) in mediastinal lymph node staging in patients undergoing surgery for non-small cell lung cancer (NSCLC).

Material And Methods: This retrospective study included 113 consecutive patients and 120 resected NSCLCs; 22 patients received neoadjuvant treatment. We compared the findings on preoperative F-FDG PET-CT studies with the postoperative pathology findings.

Rickettsiosis in Europe.

In Europe, rickettsioses are long-known infectious diseases. Until recently, it was thought that Mediterranean spotted fever due to Rickettsia conorii was the only tick-borne rickettsiosis in Europe. In the last decade new Rickettsia spp.

Detection of clonally related vanB2-containing Enterococcus faecium strains in two Spanish hospitals.

The aim of this study was to characterize the resistance mechanism in four clinical and five intestinal vancomycin-resistant Enterococcus faecium strains with VanB phenotype recovered from unrelated patients confined in two Spanish hospitals and to determine their clonal relationships. MIC values for vancomycin and teicoplanin were 16-32 and 0.5 microg ml-1, respectively.

[Endocarditis due to Bartonella spp. Three new clinical cases and Spanish literature review].

Introduction: Infections by Bartonella spp. include a wide spectrum of emerging and re-emerging infectious diseases, such as culture-negative endocarditis.

Methods: Description of 3 cases of endocarditis due to Bartonella spp.

[Diseases produced by Bartonella].

The genus Bartonella is cause of a broad number of emerging and re-emerging infectious diseases. Clinical manifestations depend on the implicated Bartonella sp. and the immunity of the host.

[Society and chronic wounds. Thoughts to stop invisibility].

The authors presented a conference at the 5th National Symposium on Bedsores, or Decubitus Ulcers, and Chronic Injuries which dealt with all the dimensions related to this problem: epidemiological data, economic costs, social repercussions and possible alternative treatments; their goal was to raise the consciousness of nursing professionals so that they realize decubitus ulcers are a public health problem for which a solution exists if nursing professionals so desire.

[Hydro-cellular dressing and silver sulfadiazine. Evaluation of its combination in the treatment of infected skin ulcers].

The authors carried out an observational, descriptive, prospective and multi-centric study on 49 infected lesions which had clinical signs of local infection as well as infection from a positive sprinkler method culture. These lesions were treated over a three week period with argentic sulfadiazine and a semi-permeable dressing; afterward, treatment continued for seven weeks more based on cures in a humid environment by means of a semi-permeable dressing. After three weeks of treatment, two-thirds of these lesions showed a negative exudative culture, the number of strains present in the rest of the cultures diminished to at least half of those present at the start of this study.

[Rickettsia africae infection. Three cases confirmed by PCR].

Background And Objective: African tick bite fever or Rickettsia africae infection has been recognized as an emerging health problem in the last few years. The aim of this study was to describe 3 cases of Spanish tourists who suffered from R. africae infection after visiting South Africa.

Dermacentor-borne necrosis erythema and lymphadenopathy: clinical and epidemiological features of a new tick-borne disease.

This paper describes the epidemiological and clinical features of a tick-borne disease differing somewhat from other tick-borne diseases found previously in Spain. All patients were bitten by Dermacentor marginatus or a large tick. The clinical features include a crustaceous or necrotic lesion at the site of the tick's attachment, surrounded by an erythema (erythema migrans-like) and painful regional lymphadenopathies.

Rhabdomyolysis as a result of Streptococcus pneumoniae: report of a case and review.

We report the case of a patient who presented with RM associated with bacteremic pneumococcal pneumonia and review the literature on this condition.

Human granulocytic ehrlichiosis in Europe.

Ehrlichiosis comprises a group of emerging tick-borne infectious diseases caused by obligate intracellular Gram-negative bacteria that infect leukocytes. Infections caused by members of the genus Ehrlichia have been described in animals and humans, but to date there are no convincing reports of the presence of other types of human ehrlichiosis different from human granulocytic ehrlichiosis (HGE) in Europe. The European vector is the same as that of Lyme borreliosis, the hard tick Ixodes ricinus, and HGE has a similar epidemiology to that of Borrelia burgdorferi infection.

Presence of granulocytic ehrlichia in ticks and serological evidence of human infection in La Rioja, Spain.

In order to estimate the risks of human granulocytic ehrlichiosis (HGE) in an endemic area for Lyme disease in the North of Spain (La Rioja), we collected and investigated by PCR specific to the E. phagocytophila group DNA, a total of 6870 Ixodes ricinus ticks. We also used an indirect immunofluorescence (IFI) test to study the presence of antibodies to the HGE agent in 147 human serum samples including patients with Lyme disease (LD), forestry workers, and persons with history of previous tick bite.

[Determination of antibodies against A-60 antigen for diagnosis of M. tuberculosis infection. A useful tool for rationalization of chemoprophylaxis in HIV patients].

Objective: To identify M. tuberculosis infection in HIV patients by use of PPD and an ELISA test detecting the presence of antibodies against antigen A-60 of M. bovis.

Incidence of pericardial effusion in pulmonary tuberculosis.

Tuberculosis (TB) is one cause of pericardial disease. In order to know the incidence of tuberculous pericardial effusion (TPE) in patients with pulmonary tuberculosis (PT), the factors associated with their presence and whether human immunodeficiency virus (HIV) patients have a higher risk, we analyzed different parameters and performed an echocardiography to evaluate the presence of TPE. The incidence of TPE was 14.

[Migratory erythema (Lyme borreliosis). Clinicoepidemiologic features of 50 patients].

Background And Objective: Erythema migrans (EM) is the earliest and most common manifestation of the infection caused by B. burgdorferi (Lyme borreliosis). The objective of the present work was to report the clinicoepidemiological features in a series of patients.

[Seroepidemiology of Bartonella henselae infection in HIV-infected patients].

Background: Bartonella henselae infections are closely related to numerous clinical infections of growing interest in Spain. Since immunosuppressed patients are a potential risk group for infection by this bacteria, the aim of the present was to study the seroepidemiology of B. henselae infection in a risk group (patients with HIV infection) and in a control group (donors).

[Seroepidemiology of Bartonella henselae infection in a risk group].

Background: Bartonella henselae infections are closely related to a number of clinical conditions of growing interest in our environment. As cats are the reservoir, and their bites and scratches are the main transmission mechanism, we attempted to study the seroepidemiology of the infection caused by this microorganism in a risk group of patients (cat owners) and a control group (blood donors).

Patients And Methods: October 1977.