Visceral fat as the main tomographic risk factor for COVID-19 mortality.

Background: Obesity is a risk factor for COVID-19 mortality; a BMI >35 increases the risk of death up to 12-fold; two previous studies have examined the association between visceral fat quantified by tomography and the risk of severe COVID-19, but not its association with mortality.

Objective: Examine whether tomographic findings differentiated data from patients who died of COVID-19 pneumonia from those who survived in a cohort of patients at a tertiary hospital.

Methods: This was a case-control study (1:1) in which we recruited data from patients at a tertiary care hospital in Mexico.

Effect of vitamin K1 supplementation on coronary calcifications in hemodialysis patients: a randomized controlled trial.

Background: Chronic kidney disease (CKD) is associated with several adverse cardiovascular outcomes, including coronary heart disease, heart failure, and arrhythmias. The severity of arterial calcifications predicts the risk of coronary heart disease and increases the risk of premature cardiovascular death. In experimental models, vitamin K1 supplementation appears to reduce coronary artery calcifications.

The Role of Adenosine in Overcoming Resistance in Sarcomas.

Resistance to systemic therapies in sarcomas poses a significant challenge to improving clinical outcomes. Recent research has concentrated on the tumor microenvironment's role in sarcoma progression and treatment resistance. This microenvironment comprises a variety of cell types and signaling molecules that influence tumor behavior, including proliferation, metastasis, and resistance to therapy.

[Classic presentation of neuromyelitis optica: clinical case and review of the literature].

Background: Neuromyelitis optica (NMO or Devic's syndrome), characterized by acute attacks of optic neuritis and transverse myelitis, is associated with antiaquaporin 4 antibodies (anti-NMO-IgG) and it has a higher prevalence in non-Caucasian populations, where multiple sclerosis is less common.

Clinical Case: 41-year-old man, with no significant personal medical history, presented with clinical symptoms including paresthesias in the right hemibody and homonymous hemianopsia in the left eye. Three weeks later, he developed lumbalgia associated with paresthesias in both lower limbs up to the T7 sensory level, as well as acute urinary retention, followed by paraplegia.

[Detection of ionizing radiation in operating room and hospital areas].

Background: The implementation of new medical techniques and technologies has increased occupational exposure to ionizing radiation and consequently the development of neoplasia and adverse effects on health personnel.

Objective: Have real information on the absorbed dose by healthcare personnel exposed to ionizing radiation in an operating room.

Material And Methods: TLD 100 dosimeters were used to measure absorbed doses by brightness curves.

[Dyslipidemia in high cardiovascular risk patients. Initial results from the REMEXDIS-IMSS study].

Background: There is no national registry on dyslipidemia and low-density lipoprotein cholesterol (LDL-c) goals by risk groups for atherosclerotic cardiovascular disease (ACVD) focused on beneficiaries of the Mexican Institute for Social Security (IMSS).

Objective: To determine the frequency of dyslipidemia, LDL-c goals and patients in treatment from high and very high-risk groups of ACVD.

Material And Methods: Multicenter, cross-sectional, descriptive study.

[Angiographic result with the use of adenosine before percutaneous coronary intervention in pharmacoinvasive therapy].

Background: Mexico is the country with the highest mortality from acute myocardial infarction (AMI), which is why guidelines have been established for early reperfusion in which fibrinolysis is the second most accessible method. However, there is a percentage of patients who do not achieve acceptable myocardial perfusion and this is associated with adverse cardiovascular outcomes. Different adenosine schemes have been used as an adjuvant to restore adequate myocardial perfusion.

Improving Automatic Coronary Stenosis Classification Using a Hybrid Metaheuristic with Diversity Control.

This study proposes a novel Hybrid Metaheuristic with explicit diversity control, aimed at finding an optimal feature subset by thoroughly exploring the search space to prevent premature convergence. : Unlike traditional evolutionary computing techniques, which only consider the best individuals in a population, the proposed strategy also considers the worst individuals under certain conditions. In consequence, feature selection frequencies tend to be more uniform, decreasing the probability of premature convergent results and local-optima solutions.

[Macular edema in retinal fundus images by a computational algorithm].

Background: Diabetes is a metabolic disease highly prevalent in our country that ends in disabling complications such as diabetic retinopathy and macular edema. As a high-impact socioeconomic issue, it is important to look for an early diagnostic test that also allows us to introduce a telemedicine service for the population with little access to specialized health services.

Objective: To describe the performance in discrimination of macular edema of a feature detection algorithm on retinal fundus images from diabetic patients.

Association of hTERT expression, Her2Neu, estrogen receptors, progesterone receptors, with telomere length before and at the end of treatment in breast cancer patients.

Background: Breast cancer shows significant clinical, morphologic, and molecular variation. Telomeres are nucleoprotein complexes composed of hexanucleotide repeat DNA sequence, TTAGGG, and numerous telomere-associated proteins. The maintenance of telomere length is carried out by a ribonucleoprotein called telomerase, which consists of two main components: a catalytic subunit called hTERT (human telomerase reverse transcriptase) and an RNA template called hTR (human telomerase RNA).

[Clinical outcomes of percutaneous intervention on the unprotected left main coronary artery].

Background: The debate on percutaneous coronary intervention (PCI) of the unprotected left main coronary artery (LMCA) has been constant over time.

Objective: To investigate the clinical and procedural characteristics and cardiovascular outcomes of PCI of unprotected LMCA.

Material And Methods: Observational study which included patients with unprotected LMCA disease undergoing PCI; patients with cardiogenic shock prior to the procedure were excluded.

[Critical shoulder angle as a predictor of severity in rotator cuff injuries].

Introduction: the connection between a critical shoulder angle (CSA) greater than 35° and the presence rotator cuff tears (RCT) is well known. However, it remains unidentified if there is an association between a higher CSA value and the presence of more severity RCT.

Material And Methods: cross-sectional, descriptive, observational, prospective and analytical study in which patients with RCT had their CSA evaluated by imaging and the degree of the RCT by arthroscopy.

High-Dimensional Feature Selection for Automatic Classification of Coronary Stenosis Using an Evolutionary Algorithm.

In this paper, a novel strategy to perform high-dimensional feature selection using an evolutionary algorithm for the automatic classification of coronary stenosis is introduced. The method involves a feature extraction stage to form a bank of 473 features considering different types such as intensity, texture and shape. The feature selection task is carried out on a high-dimensional feature bank, where the search space is denoted by O(2n) and n=473.

[Functional comparison between arthroscopy and open surgery for rotator cuff injuries].

Background: Rotator cuff injuries result in impaired functionality of the shoulder. The difference in shoulder functionality in patients treated with arthroscopy who required open surgery is still unknown.

Objective: To determine if there is a difference in the functional evolution of the shoulder in patients who underwent surgery due to rotator cuff lesion which began with arthroscopy and ended in open surgery.

[Clinical and radiographic factors associated with failure of the dynamic hip screw system].

Background: The most widely used fixation system for transtrochanteric fractures is the dynamic hip screw system, which has a failure prevalence of 10 to 17% and it is associated with the presence of clinical and radiographic factors.

Objective: To evaluate the association of clinical and radiographic factors with the failure of the screw system in post-operative patients for transtrochanteric hip fracture.

Material Y Methods: A case-control study was carried out.

[Evaluation of the quality of anesthetic recovery in postoperative patients].

Background: Comprehensive health care includes the evaluation of satisfaction in patient care and the quality of medical services. High-precision instruments have been used to assess the quality of recovery after anesthesia (QoR), such as the QoR-15 questionnaire, a validated and accurate assessment tool that considers aspects of emotionality, physical and psychological well-being, pain, and autonomy.

Objective: To assess QoR in postoperative patients who underwent anesthesia.

[Efficacy of intratympanic infiltration of N-acetyl cysteine in cisplatin ototoxicity].

Introduction: Currently there is no approved preventive or therapeutic pharmacological treatment to treat ototoxicity caused by cisplatin. N-acetyl cysteine (NAC) is a safe and inexpensive antioxidant that has been studied as an otoprotective alternative.

Objective: To describe the efficacy of intratympanic infiltration of NAC as prevention and treatment of ototoxicity induced in patients treated with cisplatin.

[Factors related with microbiological contamination of surgical site in patients undergoing tracheotomy].

Background: Tracheotomy is a common technique; however, microbiological contamination of the surgical site can increase morbimortality. Up to 90% of patients present a positive culture of the airway. Among the most important related factors is the lack of tracheal cannula replacement and lower airway infections.

[Analysis of life quality on patients with thoracolumbar fractures].

Background: Patients with thoracolumbar fractures with TLICS 4 classification are at the limit of surgical fixation with regards to conservative treatment; however, results in our environment are not known, which is why this study has innovative characteristics.

Objective: To determine the quality of life in patients with TLICS 4 thoracolumbar fractures using traditional fixation with regards to no fixation in a third level hospital.

Material And Methods: A cohort prospective study was carried out in patients with TLICS 4 classification thoracolumbar fractures using traditional fixation with regards to no fixation in beneficiaries from the Mexican Institute for Social Security.

[Concordance between ultrasound-arthroscopy of the shoulder in rotator cuff injury].

Background: Rotator cuff injury occurs over tendons that insert into the humeral tuberosity. Ultrasonography detects the size and extent of tendon tears. Its sensitivity and specificity range from 91-100% and 85-86%, respectively.

[Post-surgical hip complications in patients with and without a history of COVID-19].

Background: The World Health Organization (WHO) declared COVID-19 a pandemic on March 11, 2020. Patients who tested positive for COVID-19 experienced a higher overall rate of post-surgical complications and hospital mortality.

Objective: To compare the asociation of post-surgical complications presented in post-surgical hip patients with and without history of COVID-19 infection.

[Clinical features of pericarditis in patients with SARS-CoV-2].

Background: COVID-19 disease (coronavirus disease 2019) has multiple potentially fatal cardiovascular complications and pericarditis is one of them; however, if prompt treatment is given, fatal events associated to this complication decrease. Its frequency and presentation characteristics are unknown, which is why its early diagnosis is important.

Objective: To know the frequency of pericarditis secondary to COVID-19 and its presentation characteristics.

[Association between vascularization and its impact for recurrence of juvenile nasoangiofibroma].

Background: Juvenile nasoangiofibroma (JNA) is a rare, highly vascular, locally aggressive benign tumor which affects male adolescents. It accounts for 0.05-0.