Macrophage Activation Syndrome in MIS-C.

Background: Multisystem inflammatory syndrome (MIS-C) represents a diagnostic challenge because of its overlap with Kawasaki disease, Kawasaki disease shock syndrome, and toxic shock syndrome. Macrophage activation syndrome (MAS) is a frequently fatal complication of various pediatric inflammatory disorders and has been reported in MIS-C. Early diagnosis and prompt initiation by immune modulating therapies are essential for effectively managing MAS.

Efficacy of cognitive behavioural therapy for bipolar disorder: A systematic review.

Introduction: Bipolar disorder (BD) is a serious mental illness with a chronic course and significant morbidity and mortality. BD has a lifetime prevalence rate of 1%-1.5% and is characterised by recurrent episodes of mania and depression, or a mixture of both phases.

Current state and future perspectives for palliative care in Latin America with a special focus on Peru.

The evolution of palliative care in Latin America has been slow compared with other parts of the world, especially developed countries. Current data show inequality in the development of palliative care in the region and those differences are also evident within countries between urban and rural populations. Peru is situated in the low-ranking group in terms of palliative care services in Latin America.

[Factors Associated With Delirium In Patients Hospitalized During The COVID-19 Pandemic].

Objectives: To determine the risk factors associated with delirium in patients admitted to a COVID-19 Hospitalization of a general hospital during the first year of the COVID-19 pandemic.

Methods: An observational, analytical, case-control study was conducted. We analyzed 50 medical records of patients who presented delirium and 50 who did not present delirium in a COVID Hospitalization area during the period from March 2020 to March 2021.

Multimorbidity Patterns among People with Type 2 Diabetes Mellitus: Findings from Lima, Peru.

Background: Type 2 diabetes (T2DM) is a chronic condition with a high disease burden worldwide, and individuals with T2DM often have other morbidities. Understanding the local multimorbidity profile of patients with T2DM will inform precision medicine and public health, so that tailored interventions can be offered according to the different profiles.

Methods: An analysis was conducted of electronic health records (2016-2021) in one hospital in Lima, Peru.

Efficacy of Cognitive Behavioural Therapy for Bipolar Disorder: a Systematic Review.

Introduction: Bipolar disorder (BD) is a serious mental illness with a chronic course and significant morbidity and mortality. BD has a lifetime prevalence rate of 1% to 1.5% and is characterised by recurrent episodes of mania and depression, or a mixture of both phases.

Treatment outcomes for isoniazid-monoresistant tuberculosis in Peru, 2012-2014.

Background: Resistance to isoniazid is the most common form of drug-resistance in tuberculosis. However only a tiny proportion of TB patients in the world have access to isoniazid drug susceptibility testing-the widely implemented Xpert MTB/RIF technology only tests for resistance to rifampicin. Patients with isoniazid mono resistance that is not identified at baseline are treated with a standard regimen that effectively results in rifampicin mono-therapy during the latter four months of the six month treatment course, exposing remaining viable organisms to a single agent and greatly increasing the risk of development of multi drug-resistant TB.

Tuberculosis in children treated with second-line drugs under programmatic conditions in Lima, Peru.

Objective: To characterise childhood tuberculosis (TB) treated with second-line drugs (SLDs) in Lima, Peru.

Design: Results for the age groups <5 and 5-14 years were compared and treatment outcomes were assessed in cases reported between 2011 and 2015 from six districts of Lima.

Results: Of 96 reported cases, 82 were evaluated.

Programmatic management of patients with pre-extensively drug-resistant tuberculosis in Peru, 2011-2014.

Background: In Peru, a treatment approach for extensively drug-resistant tuberculosis (XDR-TB) incorporating World Health Organization Group 5 drugs and patient-centred care has achieved 65% success. To extend this approach to pre-XDR-TB patients, we evaluated this population separately.

Objective: To assess programmatic management of pre-XDR-TB.

[Ampulloma treatment with Whipple surgery. First case report in the regional hospital of Tumbes].

To report the first case of Whipple surgery performed at the Regional Hospital of Tumbes for the treatment of ampullary adenocarcinoma with successful results. A case report of a patient with diagnosis of ampullary adenocarcinoma, in whom was performed the first Whipple surgery at the Regional Hospital of Tumbes, in October, 2014. The patient diagnosed with an obstructive jaundice syndrome due to ampullary adenocarcinoma underwent Whipple surgery.