1,504 results match your criteria: "Hospital de Clínicas de Porto Alegre (HCPA).[Affiliation]"

Solar-based technologies for removing potentially toxic metals from water sources: a review.

Environ Sci Pollut Res Int

January 2025

Departamento de Ciência E Tecnologia de Alimentos, Universidade Federal de Santa Catarina, Rod. Admar Gonzaga, 1346, Itacorubi, Florianópolis, Santa Catarina, 88034-001, Brazil.

Technological advances have led to a proportional increase in the deposition of contaminants across various environmental compartments, including water sources. Heavy metals, also known as potentially toxic metals, are of particular concern due to their significant harmful impacts on environmental and human health. Among the available methods for mitigating the threat of these metals in water, solar radiation-based technologies stand out for their cleanliness, cost-effectiveness, and efficiency in removing or reducing the toxicity of heavy metals.

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The Pulmonary Artery Catheter in Modern Anesthesiology and Intensive Care: Indications, Benefits, and Limitations.

Braz J Anesthesiol

January 2025

Santa Casa de Porto Alegre, Serviço de Anestesia, Porto Alegre, RS, Brazil; Hospital Nossa Senhora da Conceição, Serviço de Anestesia, Porto Alegre, RS, Brazil; Universidade Federal do Rio Grande do Sul (UFRGS), Programa de Pós-graduação em Ciências Cirúrgicas, Porto Alegre, RS, Brazil.

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Robotic surgery is a technological milestone that directly impacts the provision of healthcare services. Procedures that utilize robotics are continuously being developed. In this context, it is important to analyze the distribution of ethical and civil liability among doctors, hospitals, and suppliers of surgical equipment in cases of alleged medical errors or adverse events that may harm patients.

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Mind the gap: the inconceivable void on the epidemiology of autism spectrum disorders in Brazil.

Braz J Psychiatry

January 2025

Graduate Program in Psychiatry and Behavioral Sciences, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil. Universidade de São Paulo, São Paulo, SP, Brazil.

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Effects of Neuraxial or General Anesthesia on the Incidence of Postoperative Pulmonary Complications in Patients Undergoing Peripheral Vascular Surgery: A Randomized Controlled Trial.

J Cardiothorac Vasc Anesth

December 2024

Programa de Pós-graduação em Ciências Pneumológicas, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil.

Objectives: Postoperative complications after major surgery, especially in vascular procedures, are associated with a significant increase in costs and mortality. Postoperative pulmonary complications (PPCs) have a notable impact on morbidity and mortality. The primary aim of this present study was to evaluate the effects of spinal anesthesia compared with general anesthesia on the incidence of PPCs in patients undergoing lower extremity bypass surgery.

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Objective: To compare the demographic and clinical profiles of oral lichen planus (OLP) and oral lichenoid lesions (OLL) diagnosed at a reference center in Southern Brazil from 2010 to 2019.

Methods: This retrospective study included 117 cases of suspected OLP submitted for biopsy. Investigated variables comprised sociodemographic profiles, medical history, harmful habits, clinical characteristics, and histopathological features.

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Introduction: Carbapenemase-producing Enterobacterales (CPE) is a global threat. We evaluate the prevalence of CPE among isolates categorized as meropenem-susceptible, but that meet the European Committee on Antimicrobial Susceptibility Testing (EUCAST) screening cut-off values for carbapenemase detection, and analyze the susceptibility of these isolates to new available drugs.

Methods: We analyzed 257 isolates from patients hospitalized in a tertiary hospital in Brazil, from July 2022 to April 2023.

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Introduction: The COVID-19 pandemic had a widespread global impact and presented numerous challenges. The emergence of SARS-CoV-2 variants has changed transmission rates and immune evasion, possibly impacting the severity. This study aims to investigate the impact of variants on clinical outcomes in southern Brazil.

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Objective: Disordered Eating Behaviors (DEB) are associated with dysfunctional changes in eating behavior, not meeting diagnostic criteria for eating disorders. DEB affects a significant percentage of individuals, yet it remains under-researched. The current study investigates the developmental trajectory and psychopathological correlates of DEB in children and adolescents in Brazil.

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Background: Substance Use Disorders are often associated with significant levels of domestic and external violence registered among abusers. This investigation aimed to evaluate the Domestic Violence Involvement (DVI) and related gender differences among Crack Cocaine Users in Brazil.

Methods: For this purpose, a secondary data analysis of a multicenter cross-sectional study involving 780 Crack Cocaine Users from 6 Brazilian capitals was performed.

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: To explore the potential of gatekeeping for specialized consultations and patient care via remote interactions with family physicians. This cross-sectional study was conducted at a tertiary hospital between November 2020 and December 2021, when specialized consultations were canceled due to the COVID-19 pandemic. Patients who were evaluated for remote consultation with family physicians were included.

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Shaping the future of anesthesia research: celebrating progress and embracing new challenges.

Braz J Anesthesiol

December 2024

Hospital de Clínicas de Porto Alegre (HCPA), Serviço de Anestesia e Medicina Perioperatória, Porto Alegre, RS, Brazil; Universidade Federal do Rio Grande do Sul (UFRGS), Instituto de Ciências Básicas da Saúde (ICBS), Departamento de Bioquímica, Porto Alegre, RS, Brazil; Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Santa Casa de Porto Alegre, Serviço de Anestesia, Porto Alegre, RS, Brazil; Hospital Nossa Senhora da Conceição, Serviço de Anestesia, Porto Alegre, RS, Brazil; Universidade Federal do Rio Grande do Sul (UFRGS), Faculdade de Medicina, Programa de Pós-graduação em Ciências Pneumológicas, Porto Alegre, RS, Brazil; Universidade Federal do Rio Grande do Sul (UFRGS), Programa de Pós-graduação em Ciências Cirúrgicas, Porto Alegre, RS, Brazil; Faculdade de Medicina da Universidade de São Paulo (FMUSP), Programa de Pós-Graduação em Anestesiologia, Ciências Cirúrgicas e Medicina Perioperatória, São Paulo, SP, Brazil. Electronic address:

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Background: The variability in patients' risk of oral mucositis (OM) has been, in part, attributed to differences in host genomics. The aim better define the role of genomics as an OM risk by investigating the association between genetic variants and the presence and severity of OM in pediatric patients with osteosarcoma (OS) undergoing chemotherapy (CT).

Methods: A longitudinal observational retrospective study was conducted.

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The hidden cost of hypotension: redefining hemodynamic management to improve patient outcomes.

Braz J Anesthesiol

December 2024

Universidade Federal do Rio Grande do Sul (UFRGS), Hospital de Clínicas de Porto Alegre (HCPA), Serviço de Anestesia e Medicina Perioperatória, Porto Alegre, RS, Brazil; Santa Casa de Porto Alegre, Serviço de Anestesia, Porto Alegre, RS, Brazil; Hospital Nossa Senhora da Conceição, Serviço de Anestesia, Porto Alegre, RS, Brazil; Programa de Pós-graduação em Ciências Pneumológicas e Programa de Pós-graduação em Ciências Cirúrgicas, UFRGS; Faculdade de Medicina da Universidade de São Paulo (FMUSP), Programa de Pós-Graduação em Anestesiologia, Ciências Cirúrgicas e Medicina Perioperatória, São Paulo, SP, Brazil.

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Impact of peripheral immune cells in experimental neonatal hypoxia-ischemia: A systematic review and meta-analysis.

Int Immunopharmacol

January 2025

Programa de Pós-Graduação em Ciências Biológicas: Fisiologia, Instituto de Ciências Básicas da Saúde (ICBS), Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil; Departamento de Fisiologia, Instituto de Ciências Básicas da Saúde (ICBS), Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil; Centro de Pesquisa Experimental, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, Brazil. Electronic address:

Infiltration of peripheral immune cells into the brain following neonatal hypoxia-ischemia (HI) contributes to increased neuroinflammation and brain injury. However, the specific roles of different immune cell types in neonatal brain injury remain poorly understood. Although existing evidence suggests a potential role for sexual dimorphism in HI outcomes, this aspect has been insufficiently investigated.

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Association between social cohesion and food insecurity among adults living in a healthcare region in southern Brazil.

BMC Public Health

December 2024

Postgraduate Program in Food, Nutrition and Health, Federal University of Rio Grande do Sul, UFRGS, Rua Ramiro Barcelos 2400, Rio Branco, Porto Alegre, RS, 90035-003, Brazil.

Article Synopsis
  • Food insecurity (FI) is increasing globally, particularly in developing countries, and this study examines the link between social cohesion in neighborhoods and FI in Brazil.* -
  • Conducted in Porto Alegre, Brazil, the research involved 400 adults and older adults, using interviews to assess FI and social cohesion, and employed statistical methods to analyze the data.* -
  • Findings indicate that stronger perceptions of social cohesion are associated with a lower likelihood of experiencing FI, suggesting that improving community support could help combat food insecurity.*
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Introduction: Amphotericin B lipid complex (ABLC) is an effective antifungal agent for treating invasive fungal infections (IFIs) even though its formulation is associated with potential adverse events, including those related to its infusion. This study aimed to analyze the incidence of acute infusion-related side effects (IRSE) associated with ABLC and their relationship with the profile of patients with oncohematological disease admitted in Brazilian reference tertiary hospitals.

Methods: This is an observational retrospective study that included clinical records of patients hospitalized, in a period of 6 years, diagnosed with probable or proved IFI and treated with at least two doses of ABLC.

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Article Synopsis
  • The study evaluated the effectiveness of telemedicine, specifically nurse phone calls, in managing type 2 diabetes for patients transitioning to primary care after discharge from a tertiary clinic.
  • In a randomized clinical trial with 147 patients, there was no significant difference in HbA1c levels (a marker of blood sugar control) after 12 months between those who received telemedicine support and those who underwent standard care.
  • Overall, both groups maintained reasonable glycemic control, indicating that transitioning to primary care, with or without additional telemedicine support, was effective and safe for managing type 2 diabetes.
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Article Synopsis
  • Inborn errors of immunity (IEI) involve various disorders that can be hard to diagnose early, as shown in a Brazilian patient with severe combined immunodeficiency (SCID) diagnosed at 6 months old due to multiple infections.
  • After undergoing hematopoietic stem cell transplantation (HSCT), the patient experienced recurrent infections and tested positive for SARS-CoV-2 multiple times over six months.
  • Whole exome sequencing revealed a damaging genetic variant in the Janus Kinase 3 (JAK3) gene, suggesting its role in disrupting protein function and contributing to SCID's pathogenesis.
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Nanomaterials and security in occupational and forensic medicine: insights from nanotoxicology.

Front Toxicol

November 2024

Department of Biomedicine and Prevention, Section of Legal Medicine, Social Safety and Forensic Toxicology, University of Rome Tor Vergata, Rome, Italy.

Nanoenergetics are defined as a class of nanomaterials that possess the ability to release energy in certain situations. These properties have been studied and deepened in recent years, so much so that nanoenergetics have been introduced into the use of the weapons industry, among others. It is therefore an emerging reality that deserves attention with regard to potential harmful effects on human and environmental health.

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Bioinformatic Multi-Strategy Profiling of Congenital Heart Defects for Molecular Mechanism Recognition.

Int J Mol Sci

November 2024

Laboratory of Medical Genetics and Evolution, Graduate Program in Genetics and Molecular Biology, Genetics Department, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre 91501-970, Brazil.

Congenital heart defects (CHDs) rank among the most common birth defects, presenting diverse phenotypes. Genetic and environmental factors are critical in molding the process of cardiogenesis. However, these factors' interactions are not fully comprehended.

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Oscillatory ventilation enhances oxygenation and reduces inflammation in an animal model of acute respiratory distress syndrome: an experimental study.

Braz J Anesthesiol

November 2024

Universidade Federal do Rio Grande do Sul (UFRGS), Faculdade de Medicina, Programa de Pós-Graduação em Ciências Pneumológicas, Porto Alegre, RS, Brasil; Hospital de Clinicas de Porto Alegre (HCPA), Porto Alegre, RS, Brasil.

Article Synopsis
  • This study compares variable mechanical ventilation with conventional ventilation in pigs with ARDS caused by oleic acid.
  • The pigs were split into two groups, one receiving standard controlled pressure ventilation and the other undergoing variable ventilation with changing PEEP levels.
  • Results showed that variable ventilation improved lung compliance and overall oxygen levels, with less lung damage observed in the variable ventilation group, suggesting it may be a better strategy for protecting lungs in ARDS cases.
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