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Irisin in thyroid diseases.

Clin Chim Acta

January 2025

Department of oncology, hematology and endocrinology, Hospital affiliated to NCO School of Army Military Medical University, Shijiazhuang 050000, China. Electronic address:

Irisin, a hormone-like adipo-myokine, has garnered considerable attention in recent years for its potential impact in metabolic diseases. Its physiological effects are similar to those of thyroid hormones, prompting numerous investigations into potential correlations and interactions between irisin and thyroid function through various in vitro and animal experiments. However, existing studies suggest that the relationship between irisin and thyroid diseases is highly complex and multifaceted.

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