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Utility of cytokines CXCL4, CXCL8 and GDF15 as biomarkers in systemic sclerosis.

Med Clin (Barc)

October 2022

Servicio de Reumatología, Hospital UyP La Fe, Valencia, Spain; Escuela de Doctorado. Universidad Católica de Valencia San Vicente Mártir, Valencia, Spain.

Background And Objectives: Systemic sclerosis (SSc) is an autoinmune disease that can affect several organs and its mortality is fundamentally related to its pulmonary involvement. There are some cytokines with high serum levels of patients with SSc. Our goal is to determine the role of CXCL4, CXCL8 and GDF15 in the physiopathology of SSc and whether they can be considered organic damage biomarkers.

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