[Translated article] Reamputation prevalence after minor feet amputations in patients with diabetic foot: A cross sectional study.

Introduction: Reported prevalence for reamputation in diabetic foot is diverse, risk factors are not clear for minor amputations. This study aims to determine the prevalence for reamputation in diabetic foot from minor amputations and to evaluate associated factors for such outcome.

Methods: Cross sectional study developed in 2 hospitals.

Reamputation prevalence after minor feet amputations in patients with diabetic foot, a cross sectional study.

Introduction: Reported prevalence for reamputation in diabetic foot is diverse, risk factors are not clear for minor amputations. This study aims to determine the prevalence for reamputation in diabetic foot from minor amputations and to evaluate associated factors for such outcome.

Methods: Cross sectional study developed in 2hospitals.

Clinical practice guideline on the use of single-operator cholangioscopy in the diagnosis of indeterminate biliary stricture and the treatment of difficult biliary stones.

Background And Aims: Single-operator cholangioscopy (SOC) offer a diagnostic and therapeutic alternative with an improved optical resolution over conventional techniques; however, there are no standardized clinical practice guidelines for this technology. This evidence-based guideline from the Colombian Association of Digestive Endoscopy (ACED) intends to support patients, clinicians, and others in decisions about using in adults the SOC compared to endoscopic retrograde cholangiopancreatography (ERCP), to diagnose indeterminate biliary stricture and to manage difficult biliary stones.

Methods: ACED created a multidisciplinary guideline panel balanced to minimize potential bias from conflicts of interest.

Specific neuropsychiatric symptoms are associated with functional decline trajectories in Alzheimer's disease and Lewy body dementia: a five-year follow-up study.

Background: Neuropsychiatric symptoms (NPS) are often overlooked and under-identified symptoms associated with dementia, despite their significant impact on the prognosis of individuals living with the disease. The specific role of certain NPS in functional prognosis remains unclear.

Aims: To determine the association of different NPS with functional decline in people living with Alzheimer's disease (AD) or Lewy body dementia (LBD).

Real-world performance of the MiniMed 780G advanced hybrid closed loop system in Latin America: Substantial improvement in glycaemic control with each technology iteration of the MiniMed automated insulin delivery system.

Aim: We studied real-world performance of MiniMed (MM) 780G system users from Argentina, Brazil, Colombia and Chile (geographical analysis), and the effect of each technology iteration of the MM system on glycaemic control (technology iteration analysis).

Materials And Methods: CareLink data from August 2020 to September 2022 were extracted. Endpoints included continuous glucose monitoring metrics.

Effectiveness of brief counselling in a hospital setting for smoking cessation and risky alcohol drinking reduction: randomised clinical trial protocol.

Introduction: Chronic diseases are a public health problem, and 80% of them are related to modifiable risk factors such as unhealthy diet, physical inactivity, smoking, and risky alcohol consumption. Although the intervention in smoking and hazardous alcohol drinking has proven to be effective in Primary Care, it is unknown whether it works in the same way in the hospital setting.

Objective: To evaluate the effectiveness of brief counselling in order to modify the stage of change in smokers and at-risk drinkers treated in a high complexity hospital.

Phenotypic Characteristics and Copy Number Variants in a Cohort of Colombian Patients with VACTERL Association.

VACTERL association (OMIM 192350) is a heterogeneous clinical condition characterized by congenital structural defects that include at least 3 of the following features: vertebral abnormalities, anal atresia, heart defects, tracheoesophageal fistula, renal malformations, and limb defects. The nonrandom occurrence of these malformations and some familial cases suggest a possible association with genetic factors such as chromosomal alterations, gene mutations, and inherited syndromes such as Fanconi anemia (FA). In this study, the clinical phenotype and its relationship with the presence of chromosomal abnormalities and FA were evaluated in 18 patients with VACTERL association.

Ethical guidelines on cardiopulmonary resuscitation in the context of the COVID-19 pandemic in Colombia.

The pandemic caused by COVID19 is associated with an increase in the number of cases of cardiorespiratory arrest, which has resulted in ethical concerns regarding the enforceability of cardiopulmonary resuscitation, as well as the conditions to carry it out. The risk of aerosol transmission and the clinical uncertainties about the efficacy, the potential sequelae, and the circumstances that could justify limiting this procedure during the pandemic have multiplied the ethical doubts on how to proceed in these cases. Based on ethical and legal grounds, this paper offers a practical guide on how to proceed in the clinical setting in cases of cardiopulmonary arrest during the pandemic.

Single-slice Alzheimer's disease classification and disease regional analysis with Supervised Switching Autoencoders.

Background: Alzheimer's disease (AD) is a difficult to diagnose pathology of the brain that progressively impairs cognitive functions. Computer-assisted diagnosis of AD based on image analysis is an emerging tool to support AD diagnosis. In this article, we explore the application of Supervised Switching Autoencoders (SSAs) to perform AD classification using only one structural Magnetic Resonance Imaging (sMRI) slice.

[Quality of life related to health in the Colombian population: how do Colombians perceive their health condition?].

Objective: To determine the perception about quality of life related to health in the adult population of Colombia.

Methods: Population-based survey applied on a representative sample of the Colombian rural and urban population, aged 18 years or more. Quality of life related to health was measured using the generic EQ5D instrument and the analogue visual scale as part of the fourth National Mental Health Survey.

GRADE Evidence to Decision (EtD) frameworks for adoption, adaptation, and de novo development of trustworthy recommendations: GRADE-ADOLOPMENT.

Background: Guideline developers can: (1) adopt existing recommendations from others; (2) adapt existing recommendations to their own context; or (3) create recommendations de novo. Monetary and nonmonetary resources, credibility, maximization of uptake, as well as logical arguments should guide the choice of the approach and processes.

Objectives: To describe a potentially efficient model for guideline production based on adoption, adaptation, and/or de novo development of recommendations utilizing the Grading of Recommendations Assessment, Development and Evaluation (GRADE) Evidence to Decision (EtD) frameworks.

Clinical and economic benefits of integrated pump/CGM technology therapy in patients with type 1 diabetes in Colombia.

Objective: To assess the long-term clinical and economic impact of integrated pump/CGM technology therapy as compared to multiple daily injections (MDI), for the treatment of type 1 diabetes (T1D) in Colombia.

Methods: The CORE Diabetes Model was used to simulate a hypothetical cohort of patients with T1D. Mean baseline characteristics were taken from a clinical study conducted in Colombia and a healthcare payer perspective was adopted, with a 5% annual discount rate applied to both costs and outcomes.

[Spontaneous speech prosody and discourse analysis in schizophrenia and Fronto Temporal Dementia (FTD) patients].

Unlabelled: Patients with schizophrenia and Frontotemporal Dementia (FTD) in their linguistic variants share some language characteristics such as the lexical access difficulties, disordered speech with disruptions, many pauses, interruptions and reformulations. For the schizophrenia patients it reflects a difficulty of affect expression, while for the FTD patients it reflects a linguistic issue.

Methods: This study, through an analysis of a series of cases assessed Clinic both in memory and on the Mental Health Unit of HUSI-PUJ (Hospital Universitario San Ignacio), with additional language assessment (analysis speech and acoustic analysis), present distinctive features of the DFT in its linguistic variants and schizophrenia that will guide the specialist in finding early markers of a differential diagnosis.

[Pain prevalence in patients with and without OSAHS subjected to a polysomnogram: A cross-sectional study].

Background And Objectives: Sleep disturbances apparently have a negative effect on pain or the appearance of pain itself. This suggests the need to determine whether there could be a relationship between obstructive sleep apnea-hypopnea syndrome (OSAHS) and this phenomenon. The objective of this study was to determine the pain prevalence in a population who underwent polysomnography.

[Recommendations for smoking cessation in Colombia].

Introduction: Chronic diseases represent the greatest burden of disease in Colombia for which smoking is the major risk factor.

Objectives: To provide clinical practice recommendations based upon efficacy and safety of smoking cessation therapies for Colombian adults.

Materials And Methods: An adaptation of clinical practice guidelines (CPG) based on the ADAPT methodology was performed.

[Alternative therapies for smoking cessation: clinical practice guidelines review].

Background: smoking is a chronic disease in the group of addictions and its treatment includes two components:psychosocial and pharmacological intervention. Other types of therapeutic approaches have been used as treatment options for tobacco addiction. Acupuncture, hypnosis and homeopathy are the most used nonconventional interventions.

[Introduction to Exploratory Factor Analysis (EFA)].

Introduction: Exploratory Factor Analysis (EFA) has become one of the most frequently used statistical techniques, especially in the medical and social sciences. Given its popularity, it is essential to understand the basic concepts necessary for its proper application and to take into consideration the main strengths and weaknesses of this technique.

Objective: To present in a clear and concise manner the main applications of this technique, to determine the basic requirements for its use providing a description step by step of its methodology, and to establish the elements that must be taken into account during its preparation in order to not incur in erroneous results and interpretations.

The (de)construction of a psychiatric diagnosis: PTSD among former guerrilla and paramilitary soldiers in Colombia.

The demobilisation of guerrillas and paramilitaries in Colombia, also known as irregular armed groups, has raised the question among mental health professionals as to whether ex-combatants who have had repeated exposure to stressful events might meet the requirements for posttraumatic stress disorder (PTSD). Upon arrival at a psychiatric clinic in Bogotá, 76 patients were evaluated by a group of mental health professionals with experience in this diagnosis. Contrary to clinicians' expectations, there was a conspicuous lack of PTSD among this population.

[Prevalence of glycemic control and associated factors in type 2 diabetes mellitus patients at the Hospital Universitario de San Ignacio, Bogotá-Colombia].

Introduction: Diabetes mellitus is a common disorder worldwide that produces significant morbi-mortality that could be reduced with proper glycemic control.

Objective: Estimate the prevalence of glycemic control in type-2 diabetic patients and explore its association with personal, clinical and familial factors.

Materials And Methods: We conducted a cross-sectional study with 150 type-2 diabetic patients from a chronic diseases program at the Hospital Universitario San Ignacio in Bogota.

Oral antibiotics versus parenteral antibiotics for severe pneumonia in children.

Background: Acute respiratory infection (ARI) is one of the leading causes of morbidity and mortality in children under five years of age in developing countries. When hospitalisation is required, the usual practice includes administering parenteral antibiotics if a bacterial infection is suspected. This has disadvantages as it causes pain and discomfort to the children, which may lead to treatment refusal or reduced compliance.

Laparoscopic repair for perforated peptic ulcer disease.

Background: Perforated peptic ulcer is a common abdominal disease that is treated by surgery. The development of laparoscopic surgery has changed the way to treat such abdominal surgical emergencies. The results of some clinical trials suggest that laparoscopic surgery could be a better strategy than open surgery in the correction of perforated peptic ulcer but the evidence is not strongly in favour or against this intervention.

Clinical characteristics and patterns of medication use of migraneurs in Latin America from 12 cities in 6 countries.

Objective: The objective of this study was to document the clinical characteristics of migraine and patterns of medication use in residents > or =15 years old in 12 Latin American urban communities.

Background: Few large-scale population studies have established the symptoms and disability associated with migraine with or without aura in Latin American urban communities or the pattern of medication use in these regions.

Methods: In this study, subjects in 12 urban communities, from 6 Latin American countries, were surveyed with a validated face-to-face interview questionnaire based on International Headache Society criteria for migraine.

Necropsy by magnetic resonance in a case of conjoined thoracopagus twins.

A case of thoracopagus conjoined stillborn twins studied with magnetic resonance imaging (MRI) is presented. Due to the parents' denial of authorization for an autopsy of the fetuses, the MRI study was performed as an alternative to necropsy. High-resolution images of the fetuses demonstrated relevant anatomic features, providing noninvasive pathological insight with preservation of the fetal specimen.