1,374 results match your criteria: "Hospital Universitario San Cecilio[Affiliation]"

Importance: Although clinical practice guidelines exist for the treatment of infantile hemangiomas (IHs), recommendations are heterogeneous, and wide practice variations in IH management have been reported.

Objective: To analyze the degree of agreement in treatment choices for IH among pediatric dermatologists in North America and Europe and assess whether there are differences across IH risk categories.

Design, Setting, And Participants: This cross-sectional interrater and intrarater agreement study was conducted through a survey based on the Spanish Academy of Dermatology and Venereology IH prospective cohort.

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Breast milk is the best source of nourishment for both full-term and preterm newborns. However, in preterm newborns, exclusive breastfeeding can lead to nutritional deficiencies, with short- and long-term consequences on growth and neurocognitive development. Breast milk fortification is a widely used strategy to provide an adequate nutritional profile to these patients.

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[Scombroidosis. A diagnosis to consider].

Semergen

December 2024

Servicio de Dermatología, Hospital Universitario San Cecilio, Instituto de Investigación Biosanitaria (ibs) de Granada, Granada, España. Electronic address:

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Article Synopsis
  • Recent developments in understanding AD have highlighted the OX40 receptor's role, leading to new treatments that block the OX40 ligand, which have shown considerable improvement in patients with moderate to severe AD.
  • A thorough review of anti-OX40 treatments suggests they could be a promising option for AD management, but further studies are necessary to evaluate their long-term effectiveness in treating the disease.
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  • The study was a cross-sectional analysis aimed at evaluating if degenerative cervical myelopathy (DCM) contributes to the risk of major fragility fractures, particularly hip fractures, in older patients.
  • Researchers targeted patients aged over 65 who had experienced hip fractures, finding that 15.6% showed signs of myelopathy, and the confirmed prevalence of DCM was estimated at 10.5%.
  • The findings suggest that specific clinical signs such as hypertonic reflexes and cervical pain are important for diagnosing DCM, indicating a potentially significant link between DCM and hip fractures in the elderly.
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Effects of an intervention with EVOO and physical exercise in systemic lupus erythematosus patients: Efinutriles trial protocol.

Contemp Clin Trials

November 2024

Department of Nursing, Faculty of Health Sciences, University of Granada, 18071 Granada, Spain; MP07-Bases Fisiopatología y Terapéutica Médica, Instituto de Investigación Biosanitaria (ibs.GRANADA), 18014 Granada, Spain.

Article Synopsis
  • The study explores how combining extra virgin olive oil (EVOO) and a physical exercise program can potentially improve health outcomes for patients with systemic lupus erythematosus (SLE).
  • It involves a 24-week clinical trial with 90 participants split into three groups: a control group, one taking EVOO supplements, and one taking both EVOO and participating in a health promotion and exercise program.
  • The trial aims to assess various health metrics like disease activity, cardiovascular risk, and physical fitness, to determine if this combined approach offers significant benefits for SLE patients.
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Clinical-Epidemiological Profile, and Treatment Response in Relation to Associated Atopic Comorbidity in Atopic Dermatitis. Experience From the BIOBADATOP Registry.

Actas Dermosifiliogr

November 2024

Servicio de Dermatología, Hospital Universitari Germans Trias i Pujol, Germans Trias i Pujol Research Institute (IGTP), Badalona, Barcelona, España; Departament de Medicina, Universitat Autònoma de Barcelona (UAB), Barcelona, España.

Article Synopsis
  • A study was conducted on patients with atopic dermatitis (AD) to explore the impact of atopic comorbidities like asthma and allergic rhinitis on their treatment response.
  • Data was collected from the BIOBADATOP registry, involving 509 patients, mostly adults with severe AD, and analyzed for associations between atopic comorbidities and clinical characteristics.
  • Results indicated that patients with personal atopic comorbidities had more severe symptoms and a higher history of treatments, but no significant differences in treatment response were found after 6 and 12 months, suggesting a need for longer follow-up.
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  • This study analyzed new circulating markers related to macrovascular complications (MVC) in patients with type 2 diabetes mellitus (T2DM) by comparing controls, patients with T2DM, and those with T2DM and vascular complications.
  • Results showed significant differences in the expression of specific microRNAs (miRs) between groups, particularly in miR-126a-3p, which was decreased in patients with vascular complications.
  • The study identified predictive models using various biomarkers, including HbA1c, creatinine, total cholesterol, and specific miRs, suggesting new avenues for understanding and predicting MVC in individuals with T2DM.
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  • Multidrug-resistant (MDR) bacteria are a major global health issue, particularly in intensive care units (ICUs) where high antibiotic use contributes to resistance.
  • This study evaluated the effects of a Selective Digestive Decontamination (SDD) protocol on antibiotic use and colonization by carbapenemase-producing Enterobacterale (CPE) in an ICU over two years.
  • Results showed that implementing SDD significantly reduced overall antibiotic consumption (especially carbapenems) and colonization rates of CPE, indicating it could be an effective approach to combat antimicrobial resistance in critical care without promoting MDR bacteria.
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  • Fostamatinib is an approved treatment for adults with chronic immune thrombocytopenia (ITP) but there's limited research on tapering doses and achieving remission after stopping the drug.
  • A study involving 61 patients examined the safety and effectiveness of fostamatinib during and after dose tapering, noting that complete platelet response was typically achieved within 28 days.
  • Results showed that most patients maintained platelet counts above 100 × 10/L after discontinuation, with a low relapse rate, suggesting that tapering could lead to sustained remission, though further research on tapering strategies is needed.
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Article Synopsis
  • The rise of glucose sensors and insulin pumps has improved diabetes management, but there's been an increase in contact dermatitis cases linked to these devices due to certain allergens.* -
  • Isobornyl acrylate (IBOA) is a major allergen found in some glucose sensors, leading to its removal from specific products, yet it still appears in many others.* -
  • The potential benefits of these diabetes devices can be overshadowed by allergic reactions, prompting dermatologists to work with endocrinologists and manufacturers to find alternative solutions for affected patients.*
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Article Synopsis
  • Patch test outcomes can be affected by age, but there are mixed findings on how age impacts these results.
  • The study involved over 13,000 patients and revealed that middle-aged adults (31-65 years) had the highest rates of positive skin sensitisation results, particularly for certain substances like nickel and potassium dichromate.
  • Overall, while age does influence some patch test results, most allergens showed consistent reactivity across ages, underscoring the importance of standard testing regardless of age.
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Article Synopsis
  • * The MEASURE-AD trial was conducted to gather comprehensive data on the burden of AD, using both patient and physician feedback, focusing on adults with moderate-to-severe cases.
  • * Results from the Spanish cohort revealed that patients with higher disease severity (EASI scores 21.1-72) experienced greater symptom burden, mental health issues, reduced quality of life, increased healthcare usage, and higher out-of-pocket costs compared to those with lower severity scores.
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Nutritional and potential health benefits of chufa oil, olive oil, and anhydrous milk fat against gallstone disease in a C57BL/6N mouse model.

Front Nutr

September 2024

Grupo de Investigación en Sanidad Animal y Zoonosis (GISAZ), Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad de Córdoba, Córdoba, Spain.

Article Synopsis
  • Dietary lipids, including plant oils, have significant implications on heart health and diseases like cardiovascular issues, but there's limited research on specific oils like chufa oil, olive oil, and anhydrous milk fat (AMF) in relation to atherosclerosis in mice.
  • In a study with 4-week-old C57BL/6N male mice, those fed with AMF had the highest occurrence of gallstones (85.7%), while chufa oil resulted in the lowest gallstone formation (42.9%) and reduced serum cholesterol levels.
  • Despite differences in food intake, body weight remained unchanged across groups, and chufa oil demonstrated benefits for cholesterol metabolism without harmful nutritional effects, although gallstone formation was a common
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Article Synopsis
  • - In 2017, the Spanish Academy of Dermatology created the Minimal Disease Activity (MDA) criteria to assess psoriasis severity, and this study aimed to evaluate its nationwide application across Spain.
  • - The study included 830 psoriasis patients, showing that over 59% did not meet MDA criteria, with significant variances observed based on region, sex, age, and treatment type.
  • - Results indicated that patients using biological therapies had better MDA compliance compared to those on other treatments, suggesting a need for more effective management of psoriasis across different demographics.
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Exposure to bisphenols, parabens, and benzophenones in colostrum breast milk of Panamanian women: A pilot study from the PA-MAMI cohort.

Sci Total Environ

December 2024

Instituto de Investigación Biosanitaria de Granada (ibs. GRANADA), E-18012 Granada. Spain. Electronic address:

Article Synopsis
  • This study investigates the presence of non-persistent endocrine-disrupting chemicals (EDCs), including bisphenols, parabens, and benzophenones, in the colostrum of Panamanian mothers to understand their breastfeeding influences.
  • Results showed that all colostrum samples contained multiple EDCs, with bisphenol A (BPA) being the most common at a detection rate of 91.7%, highlighting potential environmental exposures.
  • The analysis also indicated that factors such as maternal residence, diet, and personal care products influenced EDC concentrations, suggesting the need for preventive measures to ensure safe breastfeeding practices.
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[Translated article] Management of spinal deformities caused by osteoporotic vertebral fractures.

Rev Esp Cir Ortop Traumatol

October 2024

Unidad de Patología de Columna, Servicio de Traumatología, Fundación Jiménez Díaz, Madrid, Spain.

Article Synopsis
  • - Osteoporosis and fragility significantly affect how patients with deformities from osteoporotic vertebral fractures (OVF) are treated, posing challenges for both medical and surgical management.
  • - There is a growing need for a specific classification system for these deformities, which could be enhanced by artificial intelligence and machine learning for better predictive analysis in treatment planning.
  • - The approach emphasizes personalized treatment solutions focusing on preoperative optimization, with a recommendation for minimally invasive techniques to improve recovery and minimize complications.
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