First trimester abnormal profile and facial angle. Early features of anterior cephalocele.

We present a first trimester scan suspicious of fetal anterior cephalocele due to the finding of a fetus with an abnormal profile and an abnormal facial angle, with a subsequent early confirmation at 16 weeks of gestation.

High prevalence of asthma and allergic diseases in children aged 6 to [corrected] 7 years from the Canary Islands. [corrected].

Objective: To investigate the prevalence of bronchial asthma and allergic diseases in schoolchildren from the Canary Islands, Spain.

Methods: Cross-sectional study following the methodology of ISAAC (International Study of Asthma and Allergies in Childhood), which uses standardized and validated questionnaires. The study participants were children aged between 6 and 7 years attending schools in Las Palmas de Gran Canaria, Canary Islands, Spain.

Concordance between the Piko - 1 portable device and pneumotachography in measuring PEF and FEV(1) in asthmatic children.

Objective: To assess concordance in the measurement of peak expiratory flow (PEF) and forced expiratory volume ino ne second (FEV(1)) between the portable device Piko-1 (Ferraris) and a pneumotachograph.

Patients And Methods: Forced spirometry (Master Screen Jaeger) was performed according to ATS/ERS norms, selecting the best value of three curves, and three measurements with the Piko-1 were recorded the recommendations of the manufacturer.

Results: Eighty patients between 5-18 years of age were studied.

Bilateral ovarian Burkitt's lymphoma.

Primary ovarian lymphoma is a rare entity. We submit a case of a 34-year-old black patient presenting with a bilateral adnexal tumor. She underwent hysterectomy with double salpingo-oophorectomy followed by polychemotherapy treatment.

Epileptic status refractory to conventional treatment caused by vitamin B6 deficiency.

Epileptic seizures due to pyridoxine deficiency, although rare, are known to occur. They are characterized by untreatable convulsions during childhood. We present the case of an epileptic status resistant to conventional treatment in a 29-year-old woman, with no previous history of epileptic seizures, in the 29th week of pregnancy, who responded to the intravenous administration of pyridoxine.

Carbohydrate metabolism changes in cystic fibrosis.

Aims: To assess the prevalence of impaired glucose tolerance (ITG) and diabetes mellitus (DMRCF) in a group of patients with cystic fibrosis (CF). To study clinical status-related variables and to compare age with the evolution of their carbohydrate metabolism (CHM).

Patients And Methods: Thirty patients with CF (1.

[Assessment of the immigrant child].

In the last twenty years Spain has turned into one of the principal countries recipients of foreign population. As consequence of this massive entry of people, our country is among the first ones of Europe for interannual increase of population. The concept of immigrant child is very wide and includes minors of very diverse characteristics, as the proceeding from international adoptions, the children coming from developing countries or those that come from other developed countries.

Successful term delivery following conservative management for villoglandular papillary adenocarcinoma of the uterine cervix: A case report.

Background: Villoglandular papillary adenocarcinoma (VPA) is a rare subtype of adenocarcinoma of the uterine cervix. A conservative surgical approach is considered feasible. Only three cases of VPA and pregnancy have been reported.

[Docetaxel in combination with cisplatin for first-line treatment of locally advanced or metastatic non-small cell lung cancer: meta-analysis of randomized and controlled clinical trials].

Background And Objective: Recent approval of docetaxel in combination with cisplatin (DP) for non-small cell lung cancer (NSCLC) treatment means that an assessment of its effectiveness and toxicity is necessary. The aim of this study was to evaluate docetaxel/cisplatin combination versus other cisplatin-based regimens as the front-line treatment of metastatic or locally advanced NSCLC.

Material And Method: We searched randomized and controlled phase III clinical trials comparing DP versus other cisplatin combinations.

[Intermittent mandatory ventilation].

Intermittent mandatory ventilation (IMV) is a mode of ventilation that allows the patient to make spontaneous breaths during the expiratory phase of mandatory ventilator breaths. There are two types of IMV according to whether respirator breaths are synchronized with the patient's respiratory efforts: Non-synchronized IMV and synchronized IMV (SIMV), and according to whether SIMV is volume- or pressure programmed. The main advantage of SIMV is that the respirator delivers the preset ventilator pressure and rate while allowing the patient to breath spontaneously, thus facilitating progressive weaning from mechanical ventilation.

[Vesico-uterine fistula, a rare complication of cesarean section].

We present the case of a vesicouterine fistula secondary to a caesarean section indicated due to the disproportion the pelvis and the head of the baby. This kind of fistula is due fundamentally to obstetric causes, especially to caesarean sections in developed countries and to prolonged labour in developing countries. The commonest clinical presentation is urinary incontinence in the form of continuous or intermittent urinary leaks.

[Our experience with the use of Biobrane in the treatment of burns and other injuries in children].

Burns in the pediatric age are accidents which cause a lot of trauma, on the one hand because of their immediate consequences and on the other hand because of the severity of the pain, the amount of times the dressings need to be change, the lengthy hospital stay and the scars that remain for life. Between 1995 and 2000 we have treated 196 children, (4 months to 14 years old), with Biobrane: 141 patients affected of first and second degree burn injuries, 45 skin donor sites covering, 4 reinforcing of meshed autografts, 3 traumatic dermoabrasions, 2 extirpation of post-traumatic cutaneous tattoo and 1 Toxic epidermic necrolisis. Advantages noticed at the end of the treatment: Excellent skin healing.

[Diagnostic approach and treatment of inherited mitochondrial fatty acid oxidation disorders].

Inherited mitochondrial fatty acid oxidation disorders are a complex set of genetically-based diseases in which up to 22 different entities are currently recognized. Their incidence is probably underestimated because a high level of diagnostic suspicion is required for their detection. Their clinical spectrum and prognosis are variable.

Cord blood levels of cytokines as predictors of early neonatal sepsis.

Aim: To investigate whether cord blood levels of C-reactive protein, interleukin-1beta, interleukin-6, interleukin-8, tumour necrosis factor-alpha and the soluble receptor of interleukin-2, are useful markers in the diagnosis of early neonatal sepsis.

Design: Umbilical cord blood samples were obtained at birth from 261 neonates, but 5 of these newborns were excluded from the study. Group I included 10 newborns that developed early neonatal sepsis with a positive blood culture; Group II included 11 newborns with non-infectious perinatal diseases; Group III, which served as the control group, included 10 randomly selected patients, matched for gestational age, among the 235 healthy newborn babies.

Early sepsis, obstructive jaundice and right-sided diaphragmatic hernia in the newborn.

A male newborn was admitted to our Unit because of early sepsis and shock. He required antimicrobial therapy and mechanical ventilation and initially did well, although he exhibited jaundice and cholestasis. During the second week he deteriorated, with radiological opacification of the right hemithorax and pleural effusion, and did poorly in spite of antibiotical therapy and drainage of the effusion.

[Study of urinary outflow in pregnancy].

Anatomical and physiological changes in the urinary tract develop during pregnancy. These changes may affect the urinary outflow. Urinary symptoms may develop during pregnancy in previously asymptomatic patients.

[Brachial plexus palsy associated with birth. A review of 30 cases].

Objective: Our objective was to perform an updated analysis of the incidence and risk factors during pregnancy and labor related to obstetrical brachial palsy.

Patients And Methods: A retrospective study of all cases of brachial palsy associated with birth detected in our hospital between January 1994 and March 1998 was performed. Data recorded included age of mother, parity, gestational age at the moment of birth, type of birth, presentation, duration of delivery, sex of child, weight, Apgar test at 5 minutes, arterial pH of umbilical cord, type of brachial palsy, side affected and association with other injuries.

[Prospective study with auditory evoked potentials of the brain stem in children at risk].

Objective: The aim of this study was to evaluate methods of hypoacusis screening.

Patients And Methods: The early detection of audition problems is vital for quick rehabilitation. For this reason, resting on the criteria of the Comisión Española para la Detección Precoz de la Hipoacusia (Spanish Commission for the Early Detection of Hypoacusis), we have carried out a prospective study, from January to May 1998, evaluating patients at risk of suffering from hypoacusis.