20 results match your criteria: "Hospital Universitario Infantil Virgen del Rocio[Affiliation]"
Nutrients
March 2023
Hospital Universitario Puerta de Hierro, Majadahonda, 28222 Madrid, Spain.
The worldwide prevalence of asymptomatic coeliac disease (CD) is increasing, which is in part due to the routine screening of children with risk factors. Both symptomatic and asymptomatic patients with CD are at risk of long-term complications. The objective of this study was to compare the clinical characteristics of asymptomatic and symptomatic children at the time of CD diagnosis.
View Article and Find Full Text PDFCeliac disease is strongly associated with HLA DQ, specifically with haplotypes. DRB1*03-DQA1*05:01/DQB1*02:01 (DQ2.5),DRB1*07-DQA1*02:01/DQB1*02:02 (DQ2.
View Article and Find Full Text PDFJ Pediatr Gastroenterol Nutr
December 2022
From the Hospital Universitario y Politécnico La Fe, Valencia, Spain.
Objectives: The objective of this study was to assess the association between serological markers and changes of the intestinal mucosa in children with celiac disease (CD).
Methods: Clinical data from CD patients under 15 years old were collected from the participating centers in an on-line multicenter nationwide observational Spanish registry called REPAC-2 (2011-2017). Correlation between anti-tissue transglutaminase antibodies (t-TGA) levels and other variables, including mucosal damage and clinical findings (symptoms, age, and gender), was assessed.
J Pediatr Gastroenterol Nutr
June 2022
Department of Paediatrics, Hospital Universitario Puerta de Hierro, Majadahonda.
Objectives: Over the last several decades, there has been a tendency towards a predominance of less symptomatic forms of coeliac disease (CD) and an increase in the patient age at diagnosis. This study aimed to assess the clinical presentation and diagnostic process of paediatric CD in Spain.
Methods: A nationwide prospective, observational, multicentre registry of new paediatric CD cases was conducted from January 2011 to June 2017.
Cir Pediatr
January 2020
Pediatric Surgery Group (PSG). Fundación Hospitalaria, Centro de Salud Materno Infanto Juvenil. Buenos Aires (CABA), Argentina.
Objective: Recent publications report early discharge and low opioid requirements after minimally invasive pectus excavatum repair treated with bilateral intercostal nerve cryoablation. Our aim is to report our initial experience with this technique.
Material And Methods: Retrospective analysis of medical records of patients undergoing bilateral thoracoscopic cryoanalgesia during minimally invasive pectus excavatum repair within our institution from September 2018 to March 2019.
Nefrologia (Engl Ed)
August 2020
Servicio de Nefrología, Hospital Universitario Virgen Macarena, Sevilla, España.
Patients with chronic kidney disease in the hemodialysis program are exposed to large amounts of water, as this constitutes about 96% of the dialysis fluid. It is known that the use of better quality water decreases the state of chronic inflammation in dialysis patients. Disinfection as part of water treatment plays an important role in meeting the established quality standards; currently, heat disinfection is highly recommended, however its dose is not clearly established in the literature.
View Article and Find Full Text PDFAn Pediatr (Engl Ed)
March 2019
Sección de Gastroenterología, Hepatología y Nutrición Pediátrica, Hospital Universitario La Fe, Valencia, España.
Non-IgE-mediated cow's milk allergy is a frequent disorder in paediatrics. As patients might be seen by professionals from different specialties and levels of expertise, a great variability in diagnostic procedures and disease monitoring is commonly observed. Therefore, four scientific societies involved in its management have developed a consensus document providing specific recommendations related to its prevention, diagnosis, treatment and follow up.
View Article and Find Full Text PDFPediatr Infect Dis J
June 2016
Department of Paediatric Infectious Diseases and Immunopathologies, Hospital Universitario Infantil Virgen del Rocio, Sevilla, Spain, Instituto de Investigación Biomédica, Sevilla (IBiS), Sevilla, Spain Paediatric Hematology Unit, Hospital Universitario Virgen del Rocio, Sevilla, Spain Department of Infectious Diseases, Microbiology and Preventive Medicine, Hospital Universitario Virgen del Rocio, Sevilla, Spain Department of Paediatric Infectious Diseases and Immunopathologies, Hospital Universitario Infantil Virgen del Rocio, Sevilla, Spain, Instituto de Investigación Biomédica, Sevilla (IBiS), Sevilla, Spain.
Data Brief
March 2016
Departamento de Bioquímica y Biología Molecular, Universidad de Córdoba, Campus de Excelencia Internacional CeiA3, Córdoba, Spain.
Surface proteins play key roles in the interaction between cells and their environment, and in pathogenic microorganisms they are the best targets for drug or vaccine discovery and/or development. In addition, surface proteins can be the basis for serodiagnostic tools aiming at developing more affordable techniques for early diagnosis of infection in patients. We carried out a proteomic analysis of a collection of pediatric clinical isolates of Streptococcus pneumoniae, an important human pathogen responsible for more than 1.
View Article and Find Full Text PDFRev Chil Pediatr
December 2016
Unidad de Gestión Clínica de Pediatría, Hospital Universitario Puerta del Mar, Cádiz, España.
Introduction: There is no clear consensus on the management of accidental ingestion of caustic substances in paediatrics. The aim of this study was to determine the profile of the paediatric population treated due to caustic ingestion in a Healthcare Centre.
Patients And Method: A descriptive study was conducted on patients treated for the ingestion of caustic substances in our hospital during the period 2008-2011.
Mol Cell Proteomics
October 2015
From the ‡Departamento de Bioquímica y Biología Molecular, Universidad de Córdoba; Campus de Excelencia Internacional CeiA3; and Red Española de Investigación en Patología Infecciosa (REIPI), Instituto de Salud Carlos III, Madrid, Spain;
Pneumonia is one of the most common and severe diseases associated with Streptococcus pneumoniae infections in children and adults. Etiological diagnosis of pneumococcal pneumonia in children is generally challenging because of limitations of diagnostic tests and interference with nasopharyngeal colonizing strains. Serological assays have recently gained interest to overcome some problems found with current diagnostic tests in pediatric pneumococcal pneumonia.
View Article and Find Full Text PDFJ Proteomics
August 2015
Sección de Enfermedades Infecciosas Pediátricas e Inmunopatología, Hospital Universitario Infantil Virgen del Rocío, Sevilla, Spain. Electronic address:
Pneumococcal surface proteins are potential candidates for the development of protein-based vaccines and serological assays. The objective of the study was to develop a multiple bead-based immunoassay using Luminex xMAP® technology for the quantitation of natural antibodies against Streptococcus pneumoniae proteins and the characterization of the acute serum response following pneumococcal pneumonia in children. Sixty-four recombinantly produced pneumococcal proteins, which were selected based on their proteomic experimental identification by "shaving" live cells with trypsin followed by LC/MS/MS analysis, were coupled to fluorescent SeroMAP® beads and anti-pneumococcal specific IgG levels were determined in sera.
View Article and Find Full Text PDFJ Proteomics
June 2014
Departamento de Bioquímica y Biología Molecular, Universidad de Córdoba, Campus de Excelencia Internacional CeiA3, Córdoba, Spain; Red Española de Investigación en Patología Infecciosa (REIPI), Instituto de Salud Carlos III, Madrid, Spain. Electronic address:
Unlabelled: Extracellular vesicles are produced by many pathogenic microorganisms and have varied functions that include secretion and release of microbial factors, which contribute to virulence. Very little is known about vesicle production by Gram-positive bacteria, as well as their biogenesis and release mechanisms. In this work, we demonstrate the active production of vesicles by Streptococcus pneumoniae from the plasma membrane, rather than being a product from cell lysis.
View Article and Find Full Text PDFPediatr Infect Dis J
September 2011
Division of Pediatric Infectious Diseases, Hospital Universitario Infantil Virgen del Rocio, Sevilla, Spain.
We present a 3-year-old girl who had chronic recurrent multifocal osteomyelitis caused by Coxiella burnetii despite long-term dual antibiotic therapy. Excellent clinical response was achieved and sustained when immunomodulatory therapy with interferon-γ was initiated. This is the case of a first child who was successfully treated with interferon-γ as adjuvant therapy for chronic multifocal Q fever osteomyelitis.
View Article and Find Full Text PDFAn Pediatr (Barc)
September 2008
Servicio de Pediatría, Hospital Universitario Infantil Virgen del Rocío, Sevilla, España.
Background: Convulsions with mild rotavirus gastroenteritis were first described by Morooka in 1982. This is a process of convulsions and gastroenteritis without any changes in complementary tests. They are few cases out of Asia and they are rarely reported in Spain.
View Article and Find Full Text PDFBackground: Brimonidine is an extremely lipophilic drug which is absorbed very well through the cornea and thus crosses the blood-brain barrier. This is very important for any potential toxic effects on the CNS.
Objectives: To show the adverse effects of brimonidine and advise the need for caution in its use in the paediatric population.
Objectives: 1) To identify the profile of the cases requested for autopsy; 2) to analyze the clinocopathological discordance; 3) to investigate predictive factors for unsuspected clinically relevant diagnoses.
Patients And Method: All autopsies performed between January 1999 and December 2005 in a tertiary neonatal intensive care unit, were retrospectively reviewed. Clinicopathological concordance was assessed independently by two neonatologists and two pathologists, according to a modification of the Goldman classification.
Cir Pediatr
January 2005
Departamento de Fisiología Medica y Biofísica, Facultad de Medicina de Sevilla, Hospital Universitario Infantil Virgen del Rocio.
Unlabelled: The anorectal manometry (AM) and suction rectal biopsy (BS) are the main and accepted methods for diagnosis of Hirschsprung disease (HD). The reliability of these methods in newborns have been subject of controversy up to the present.
Material And Methods: For diagnosis of HD purpose we have performed 2227 AM records in 1744 children.
Allergol Immunopathol (Madr)
August 1999
Unidad de Alergia Infantil, Hospital Universitario Infantil "Virgen del Rocío", Sevilla, España.
The major factors contributing to asthma morbidity and mortality are underdiagnosis and inappropriate treatment. Consultation with an Allergy specialist may be appropriate for those patients with asthma who do not respond favorably to treatment. Effective treatments are available for controlling asthma symptoms, preventing exacerbations, and improving lung function so that patients can have active and productive lives.
View Article and Find Full Text PDFEnferm Infecc Microbiol Clin
December 1998
Sección de Infectología, Hospital Universitario Infantil Virgen del Rocío, Sevilla.
Background: The aim of this study was review the epidemiology of the bacterial meningitis in our area.
Material And Methods: A retrospective study was carried out of all the cases of bacterial meningitis in children with ages between two months and fourteen years, admitted in our hospital between 1986 and 1997. The following variables we analyzed: Sex, age of the patient, yearly and monthly incidence, previous antibiotic therapy, length of hospital stay, and analytical data of blood and cerebrospinal fluid.