[Variación estacional de las amputaciones en un hospital universitario de Monterrey, México (2009-2012)].

Antecedentes: Una de las principales complicaciones de la diabetes mellitus es la amputación de alguna extremidad. En todo el mundo, la prevalencia de amputaciones asociadas a la diabetes es muy variada y tiene un impacto considerable en la calidad de vida del paciente.

Objetivo: Analizar la frecuencia de las amputaciones en el Hospital Universitario Dr.

Reliability of ultrasonography to detect inflammatory lesions and structural damage in juvenile idiopathic arthritis.

Background: Musculoskeletal Ultrasonography (MSUS) is an important tool for the clinical assessment in Juvenile Idiopathic Arthritis (JIA). The objective of this study was to evaluate the reliability of MSUS to detect elementary lesions: synovitis, tenosynovitis, cartilage damage and bone erosions in the wrist and metacarpal (MCP) joints of patients with JIA.

Methods: Thirty children in various subgroups of JIA according to ILAR criteria, were included in this cross-sectional study.

Effect of ursodeoxycholic acid on glycemic markers: A systematic review and meta-analysis of clinical trials.

Ursodeoxycholic acid (UDCA) is widely used to treat liver diseases; however, its potential effect on metabolic parameters has been poorly investigated. Additionally, owing to divergent data, the objective of this meta-analysis was to evaluate the effect of UDCA on glycemic parameters in clinical trials. Clinical trials investigating the impact of UDCA treatment on glycemic markers were searched in PubMed-Medline, SCOPUS, Web of Science and Google Scholar databases (from inception to April 16, 2018).

A randomized placebo-controlled trial evaluating the effect of melatonin on sleep quality in patients with mild-moderate dementia.

Background: Patients with dementia may suffer from poor sleep quality as well as insomnia and sleep-wake cycle alterations.

Objectives: The main objective of this study was to evaluate the efficacy of melatonin in improving sleep quality.

Methods: This was a single-center randomized, double-blinded, placebo-controlled study carried out on outpatients with dementia and sleep alterations (according to Diagnostic and Statistical Manual V criteria) from January 2016 to December 2016.

Acute phase markers in obese children and adolescents with metabolic disorders.

Introduction: Obesity is a worldwide public health problem and the most common non-communicable chronic disease. It is associated with an increase in inflammatory acute phase proteins and proinflammatory cytokines.

Objective: To assess the levels of acute phase proteins in obese children and adolescents with hepatic steatosis and metabolic syndrome.

Extracellular matrix and fibroblast injection produces pterygium-like lesion in rabbits.

Background: Translational research to develop pharmaceutical and surgical treatments for pterygium requires a reliable and easy to produce animal model. Extracellular matrix and fibroblast are important components of pterygium. The aim of this study was to analyze the effect of the subconjunctival injection of fibroblast cells (NIH3T3 cell line) and exogenous extracellular matrix in rabbits in producing a pterygium-like lesion.

D-Lactate and intestinal fatty acid-binding protein are elevated in serum in patients with acute ischemic stroke.

Experimental studies suggest that the intestinal barrier is affected in ischemic stroke. D-Lactate and intestinal fatty acid-binding protein (IFABP) are markers of intestinal mucosa integrity and barrier function. Our purpose was to evaluate the serum concentrations of these markers in patients with acute ischemic stroke (AIS).

Genotypic and Phenotypic Factors Influencing Drug Response in Mexican Patients With Type 2 Diabetes Mellitus.

The treatment of Type 2 Diabetes Mellitus (T2DM) consists primarily of oral antidiabetic drugs (OADs) that stimulate insulin secretion, such as sulfonylureas (SUs) and reduce hepatic glucose production (e.g., biguanides), among others.

Septic Pulmonary Emboli and Renal Abscess Caused by in an HIV-Infected Patient.

is a common cause of bacteremia in the general population and can lead to serious metastatic infection particularly in immunocompromised persons. However, prompt diagnosis and management can result in favorable outcomes. In the following case report, the clinical course of an HIV-infected man is presented; he developed bloodstream infection (BSI) and associated complications: septic pulmonary embolism, right renal abscess, and ipsilateral renal vein thrombosis.

Volumetric lipoinjection of the fronto-orbital and temporal complex with adipose stem cells for the aesthetic restoration of sequelae of craniosynostosis.

Background: Non-syndromic craniosynostosis causes craniofacial asymmetry and may persist after cranioplasty. These postoperative asymmetries are primarily depressions. In some cases, patients may be subjected to pranks and harassment by their peers, affecting their psychosocial development.

The efficacy and adverse events of testosterone replacement therapy in hypogonadal men: A systematic review and meta-analysis of randomized, placebo-controlled trials.

Context: The efficacy and safety of testosterone replacement therapy (TRT) in hypogonadal men remain incompletely understood.

Objective: To conduct a systematic review and meta-analysis of randomized clinical trials (RCT) to determine the effects of TRT on patient-important outcomes and adverse events in hypogonadal men.

Data Sources: We searched Ovid MEDLINE, Ovid EMBASE, Ovid Cochrane Database of Systematic Reviews, Ovid Cochrane Central Register of Controlled Trials, and Scopus from inception to March 2th, 2017.

[Intrarticular infiltration of bupivacaine and magnesium sulfate in distal radius fractures. A pilot study].

Background: The distal radius fracture represent until 15% of all bone injuries in adults. The key in the recovery of mobility and functional outcomes are rehabilitation. The intra-articular application of magnesium sulphate has been used for postoperative pain.

Severe hypertriglyceridemia associated with teriflunomide in a patient with multiple sclerosis: A case report.

Objective: To describe a case of severe hypertriglyceridemia in a patient receiving teriflunomide.

Methods: This is a case study.

Results: Our patient developed severe hypertriglyceridemia (>5000 mg/dL) while on teriflunomide.

Acute Variceal Bleeding: Does Octreotide Improve Outcomes in Patients with Different Functional Hepatic Reserve?

Background: Current guidelines do not differentiate in the utilization of vasoactive drugs in patients with cirrhosis and acute variceal bleeding (AVB) depending on liver disease severity.

Material And Methods: In this retrospective study, clinical outcomes in 100 patients receiving octreotide plus endoscopic therapy (ET) and 216 patients with ET alone were compared in terms of failure to control bleeding, in-hospital mortality, and transfusion requirements stratifying the results according to liver disease severity by Child-Pugh (CP) score and MELD.

Results: In patients with CP-A or those with MELD < 10 octreotide was not associated with a better outcome compared to ET alone in terms of hospital mortality (CP-A: 0.

Effect of fibrates on glycemic parameters: A systematic review and meta-analysis of randomized placebo-controlled trials.

Aims: The aim of this meta-analysis of randomized placebo-controlled clinical trials was to assess the effect of fibrates on glycemic parameters.

Materials And Methods: Only randomized placebo-controlled trials investigating the impact of fibrate treatment on glucose homeostasis markers were searched in PubMed-Medline, SCOPUS, Web of Science and Google Scholar databases (from inception to April 11, 2017). A random-effects model and generic inverse variance method were used for quantitative data synthesis.

Modulation of Remote Ischemic Preconditioning by Proinflammatory Cytokines in Renal Transplant Recipients.

Aim: Remote ischemic preconditioning (RIPC) has been used as a strategy to reduce acute renal injury and ischemia-reperfusion injury (IRI) in renal transplantation (RT) with controversial results.

Objective: To determine if RIPC modifies IRI in cadaveric RT recipients through inflammatory mediators and graft function.

Methods: Twenty-nine RT recipients were studied, 12 in the control group (CG) and 17 in the RIPC group.

Correlation Between Incisional Biopsy Histological Subtype and a Mohs Surgery Specimen for Nonmelanoma Skin Cancer.

Background: Histological diagnosis of a clinically suspected nonmelanoma skin cancer (NMSC) is recommended before treatment. For NMSC, concordance between the histological subtype of the preoperative biopsy and the excision specimen of basal cell carcinoma (BCC) has been reported to range from 10% to 81%. No large study on the concordance between NMSC histology seen in a preoperative biopsy with the following tumour specimen from Mohs micrographic surgery (MMS) has been performed in a Latin American population.

The prognostic significance of serum XCL1 concentration in patients with acute lymphoblastic leukemia: a pilot study.

There is no information about XCL1 in patients with acute lymphoblastic leukemia (ALL). The objective of this study was to correlate the serum levels of XCL1 and survival in ALL patients. Only ALL patients older than 12 months were considered to participate.

Riley-Day Syndrome in a Hispanic Infant of Non-Jewish Ashkenazi Descent.

Riley-Day syndrome is an autosomal recessive sensory and autonomic neuropathy. Patients present a lack of fungiform papilla, alacrima and usually feeding difficulties. It is present almost exclusively in Ashkenazi Jewish individuals and has a poor prognosis.

Algorithm for Screening of Adrenal Function in Stable Patients with Cirrhosis.

Introduction And Aims: Adrenal insufficiency (AI) is common in patients with cirrhosis. We aimed to assess the presence of AI in stable patients with cirrhosis using the gold-standard insulin tolerance test (ITT) and to propose an algorithm for screening AI in these patients.

Material And Methods: We studied 40 stable patients with cirrhosis.