4,532 results match your criteria: "Hospital Universitari Germans[Affiliation]"

Importance: Cardiac surgery-associated acute kidney injury (CSA-AKI) remains a significant problem following cardiopulmonary bypass (CPB). Various strategies are proposed to attenuate CSA-AKI, including extracorporeal blood purification (EBP), but little is known about the effect of EBP through an acrylonitrile-sodium methallylsulfonate/polyethyleneimine membrane during CPB.

Objective: To determine whether the use of an EBP device in a nonemergent cardiac surgery population reduces CSA-AKI after CPB.

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Testicular large B-cell lymphoma is genetically similar to PCNSL and distinct from nodal DLBCL.

Hemasphere

October 2024

Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) Barcelona Spain.

Article Synopsis
  • * A study involving 61 TLBCL patients analyzed their genetic characteristics compared to nodal DLBCL and primary CNS large B-cell lymphomas; findings indicated that TLBCL has fewer copy number changes but more somatic mutations than nodal DLBCL.
  • * The results highlight a unique genetic profile for TLBCL, with most cases classified as MCD, indicating genetic diversity, suggesting that this lymphoma type warrants targeted treatment strategies due to its distinct biology.
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Implementation of a checklist for intravitreal injections.

Arch Soc Esp Oftalmol (Engl Ed)

November 2024

Servicio de Oftalmología, Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain; Institut Català de la Retina (ICR), Barcelona, Spain.

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Purpose: While treatments for primary brain tumors increase survival, they have cognitive sequelae. Neurocognition's anatomical distribution makes it susceptible to brain damage. This study aims to evaluate the contribution of radiotherapy on short-term cognitive impairment.

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Article Synopsis
  • Integrated approaches to mapping skin Neglected Tropical Diseases (NTDs) may optimize resource allocation, but extensive data covering multiple endemic countries was previously lacking.
  • Between March 2021 and March 2023, integrated case searches were conducted in Cameroon, Côte d'Ivoire, and Ghana, screening over 61,000 individuals for various skin conditions including yaws and other NTDs.
  • The findings revealed that 18.6% of those screened had skin lesions, with the majority being children; yaws was confirmed in a varying proportion of cases across the three countries, while scabies and fungal infections were the most commonly diagnosed conditions.
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Purpose: We aimed to describe the intensity of care and its consequences on informal caregivers of stroke survivors according to the degree of care receivers' functional dependence for activities of daily living; and to identify the factors associated with caregivers' care-related quality of life.

Methods: Cross-sectional analysis of prospective data collected in a cost-utility study alongside the RACECAT trial in Catalonia (Spain). One-hundred and thirty-two care receiver-caregiver pairs were interviewed six months after stroke.

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Article Synopsis
  • The study compares long-term mortality outcomes between revascularization (like PCI or CABG) and guideline-directed medical therapy (GDMT) in patients with heart failure and ischaemic left ventricular dysfunction.
  • Out of 408 patients, the revascularization group had a 33% mortality rate, while the GDMT group had a 43% rate, showing no significant mortality benefit for revascularization.
  • Overall, neither revascularization methods (CABG or PCI) showed a clear advantage over GDMT in reducing mortality, and further research is suggested to better understand their roles in treatment.
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  • A recent study evaluated the prevalence of potentially inappropriate medications (PIM) in hospitalized adults aged 75 and older across 16 hospitals in Spain.
  • The study included 4,183 patients and found that 23.5% were prescribed PIMs, with a notable variation in prevalence between hospitals (10% to 42.5%).
  • Benzodiazepines were the most common PIMs, and many patients continued their PIMs from pre-admission into the hospital; however, few were still prescribed at discharge, highlighting the need for better medication management for older adults.
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  • There is increasing research into how Long-COVID affects cognitive functions, utilizing neuroimaging to understand the underlying brain changes in patients experiencing cognitive impairment.
  • A study using advanced brain imaging techniques on 53 Long-COVID patients revealed significant cognitive deficits, particularly in executive functions and attention, with some correlations found between brain structure and memory performance.
  • The results suggest that Long-COVID is associated with lasting cognitive impairments due to altered brain structure and connectivity, highlighting the importance of understanding these changes for patient care.
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  • Study investigates the use of patiromer, a potassium binder, to improve the effectiveness of RAAS inhibitors in patients with heart failure and hyperkalemia.
  • In a trial with over 1,000 patients, those with hyperkalemia were able to optimize their medication while on patiromer, showing a slight reduction in serum potassium levels compared to placebo.
  • Results suggest patiromer helps patients with current hyperkalemia maintain optimal doses of medication more effectively than those with a history of hyperkalemia, enhancing treatment outcomes for heart failure management.
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Background: While selective use of antibiotics for infected pancreatic necrosis (IPN) in acute pancreatitis (AP) is recommended, studies indicate a high rate of inadequate treatment.

Methods: A search of PubMed, Scopus, and Cochrane databases was conducted, focusing on primary research and meta-analyses. Data were categorized based on core concepts, and a narrative synthesis was performed.

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Article Synopsis
  • The article reviews the 2023 activity report from the Interventional Cardiology Association of the Spanish Society of Cardiology, highlighting key trends in interventional cardiology practices in Spain.
  • A survey involving 119 hospitals revealed a slight decrease in diagnostic studies but an increase in percutaneous coronary interventions (PCI), with a notable rise in the use of drug-coated balloons and techniques for plaque modification.
  • The findings indicate a stabilization in coronary interventions while showcasing a growth in complex procedures, particularly for valvular and nonvalvular structural heart diseases, with primary PCI becoming the leading treatment for myocardial infarction.
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Purpose: Surgery close to or in contact with the ventricular system is challenging due to the complications. We sought to evaluate the effectiveness and safety of TachoSil® as a ventricular sealant in preventing complications after cranial surgery with an open ventricular system (OVS).

Methods: This is a single-center and prospective cohort study We included patients who underwent elective surgery for supratentorial craniotomy and periventricular pathology between December 2020 and November 2023.

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Purpose: To systematically review and summarize the available literature on (1) postoperative healing rates, meniscal extrusion (ME) and clinical outcomes following lateral (LMPRR) versus medial (MMPRR) root repair and (2) potential correlations between residual ME and healing outcomes.

Methods: A comprehensive literature search was conducted using the Scopus, PubMed and Embase databases. Clinical studies evaluating healing status on second-look arthroscopy and magnetic resonance imaging (MRI) after LMPRR and MMPRR were included.

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Sex Differences in Chronic Postsurgical Pain after Open Thoracotomy.

J Cardiothorac Vasc Anesth

December 2024

Department of Anesthesiology, Parc de Salut MAR, Institut Municipal d'Investigació Médica, Universitat Autónoma de Barcelona, Spain. Electronic address:

Study Objective: To determine the incidence of chronic postsurgical pain (CPSP) in women after open thoracotomy. Secondary objectives were to compare relevant patient and procedural variables between women and men.

Design: Observational cohort study.

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Article Synopsis
  • Hyperkalemia (HK) impacts the effectiveness of renin-angiotensin system (RAS) inhibitors and mineralocorticoid receptor antagonists (MRAs) in patients with heart failure with reduced ejection fraction (HFrEF).
  • The study analyzed patients with HFrEF and either HK or a history of HK during a run-in phase designed to optimize their RAS inhibitor and MRA doses using patiromer.
  • Results showed significant increases in the use of RAS inhibitors and MRAs among patients meeting the optimization criteria, indicating that patiromer helped enhance treatment for those with HK or a history of HK.
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Main Aim: In July 2022, an extensive outbreak of Mpox (monkeypox) was considered by WHO as a Public Health Emergency. The objective of this study is to describe the obtained results from a Mpox case detection program in a semi-urban healthcare area where approximately 420 Primary Care physicians work.

Design: An observational prospective study performed between June 01, 2022 and December 31, 2023.

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Aims: Real-world data show that guidelines are insufficiently implemented, and particularly guideline-directed medical therapies (GDMT) are underused in patients with heart failure and reduced ejection fraction (HFrEF) in clinical practice. The Council for Cardiology Practice and the Heart Failure Association of the European Society of Cardiology (ESC) developed a survey aiming to (i) evaluate the perspectives of the cardiology community on the 2021 ESC heart failure (HF) guidelines, (ii) pinpoint disparities in disease management, and (iii) propose strategies to enhance adherence to HF guidelines.

Methods And Results: A 22-question survey regarding the diagnosis and treatment of HFrEF was delivered between March and June 2022.

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Objective: To determine the degree of knowledge about biological therapy and biosimilars in patients with immune-mediated inflammatory diseases treated in Outpatient Pharmaceutical Care Units.

Methods: Observational, prospective, and multicenter study during the period May 2020-March 2021. A survey (9 questions) was conducted before starting treatment in which the patients' level of knowledge about biological therapy and biosimilars was assessed.

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Sex dependence of postoperative pulmonary complications - A post hoc unmatched and matched analysis of LAS VEGAS.

J Clin Anesth

December 2024

Amsterdam University Medical Center, Department of Anaesthesiology, Meibergdreef 9, 1105AZ Amsterdam, the Netherlands; Amsterdam University Medical Center, Department of Intensive Care, Meibergdreef 9, 1105AZ Amsterdam, the Netherlands.

Article Synopsis
  • The study aimed to investigate whether there are differences in postoperative pulmonary complications (PPCs) between males and females following surgery under general anesthesia, using data from the LAS VEGAS study involving 146 hospitals across 29 countries.
  • A total of 9,697 patients were analyzed in two cohorts: an unmatched cohort (55.1% female, 44.9% male) and a matched cohort (50% female and male), finding no significant differences in PPC rates between the genders in both cohorts.
  • The study concluded that, in this international patient population, the incidence of PPCs did not differ significantly between males and females, as well as noting comparable hospital stays and mortality rates.*
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Article Synopsis
  • The main goals of treating heart failure with reduced ejection fraction (HFrEF) are to lower mortality rates and reduce hospitalizations, while also improving the overall quality of life and cardiac function for patients.
  • Effective treatments such as RAS inhibitors (ACE inhibitors, ARBs, ARNIs), beta-blockers, and SGLT2 inhibitors have shown benefits in reducing mortality, hospitalization, and the risk of sudden death, as well as aiding in cardiac remodeling and renal protection.
  • The ideal HFrEF treatment should be effective across various patient profiles, taking into account individual differences and comorbidities, while maximizing overall health benefits beyond just heart function.
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Introduction And Objectives: We report the results of the 2023 Spanish catheter ablation registry.

Methods: Procedural data were collected and incorporated into the REDCap platform by all participating centers through a specific form.

Results: There were 104 participating centers in 2023 compared with 103 in 2022.

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