Infliximab in ulcerative colitis: real-life analysis of factors predicting treatment discontinuation due to lack of response or colectomy: ECIA (ACAD Colitis and Infliximab Study).

Objective: To describe clinical practice with infliximab (IFX) in ulcerative colitis (UC); identification of predictive factors for IFX treatment discontinuation due to insufficient response and for colectomy.

Material And Methods: Retrospective, multicentric and observational study including every UC IFX-treated patient in 10 Spanish hospitals. Variables analyzed: epidemiological data; variables for poor prognosis; IFX prior treatments; characteristics of the IFX treatment; time from the UC diagnosis to induction with IFX; time from induction to colectomy or until data collection.

Structural Damage to Jailed Guidewire During the Treatment of Coronary Bifurcations: Microscopic Evaluation.

Introduction And Objectives: The use of the jailed guidewire technique is highly useful when treating bifurcation lesions by provisional stenting. However, at the time of withdrawal, the guidewire can suffer damage and even fracture. The aim of this study was to evaluate structural damage in both polymer-coated and nonpolymer-coated jailed guidewires.

[Detection of adverse events in hospitalized adult patients by using the Global Trigger Tool method].

Objectives: To identify and characterize adverse events (AE) in an Internal Medicine Department of a district hospital using an extension of the Global Trigger Tool (GTT), analyzing the diagnostic validity of the tool.

Methods: An observational, analytical, descriptive and retrospective study was conducted on 2013 clinical charts from an Internal Medicine Department in order to detect EA through the identification of 'triggers' (an event often related to an AE). The 'triggers' and AE were located by systematic review of clinical documentation.

Uncommon renal masses: Perirenal extramedullary hematopoiesis and multiple lymphangiomatosis with a perirenal lymphangioma.

Objective: To present two cases of infrequent renal masses, trying to achieve the diagnosis before surgery.

Methods: We describe a case referred from the Department of Hematology in which bilateral perirrenal masses were described in the CT scan; after biopsy they where classified as extramedullary hematopoietic tissue. The other case was a patient presenting to the emergency room with dyspnea.

A clinical classification of the acute respiratory distress syndrome for predicting outcome and guiding medical therapy*.

Objective: Current in-hospital mortality of the acute respiratory distress syndrome (ARDS) is above 40%. ARDS outcome depends on the lung injury severity within the first 24 hours of ARDS onset. We investigated whether two widely accepted cutoff values of PaO2/FIO2 and positive end-expiratory pressure (PEEP) would identify subsets of patients with ARDS for predicting outcome and guiding therapy.

Epidemiology and temporal trends (2000-2012) of inflammatory bowel disease in adult patients in a central region of Spain.

Background And Aim: A growing incidence of inflammatory bowel disease (IBD) has been reported recently in southern Europe, with records of pediatric cases confirming these tendencies in Spain. Data on adult populations, however, have not been provided for over 10 years and need to be updated.

Patients And Methods: A multicenter retrospective registry of all adult patients with a diagnosis of IBD, including both Crohn's disease (CD) and ulcerative colitis (UC), attending five public hospitals covering a population of 514 368 inhabitants, was assessed.

[Multicenter program for the integrated care of newborns with perinatal hypoxic-ischemic insult (ARAHIP)].

Introduction: Newborns with perinatal indicators of a potential hypoxic-ischemic event require an integrated care in order to control the aggravating factors of brain damage, and the early identification of candidates for hypothermia treatment.

Patients And Methods: The application of a prospective, populational program that organizes and systematizes medical care during the first 6 hours of life to all newborns over 35 weeks gestational age born with indicators of a perinatal hypoxic-ischemic insult. The program includes 12 hospitals (91,217 m(2)); two level i centers, five level ii centers, and five level iii hospitals.

Pain management in Guillain-Barre syndrome: a systematic review.

Introduction: Pain is a common symptom in patients with Guillain-Barre syndrome. Intensity is moderate to severe in most cases and pain may persist after resolution of the disease.

Objective: Identify the most appropriate analgesic therapy for pain management in patients with Guillain-Barre syndrome.

Demographic, clinical, and genetic characteristics of patients with medullary thyroid cancer in the past 16 years in Castilla-La Mancha.

Objective: Medullary thyroid cancer is a rare tumor that is more aggressive and has a worse prognosis than differentiated thyroid cancer. The purpose of this study was to report the demographic, clinical, and genetic characteristics of patients seen in the health care system of the community of Castilla-La Mancha over a 16-year period.

Patients And Methods: Data were collected through a review of patients' medical records.

[Percutaneous tracheostomy through dilatation with the Ciaglia Blue Dolphin(®) method].

Objective: To describe the perioperative and postoperative complications in critically ill patients requiring percutaneous tracheostomy using the Ciaglia Blue Dolphin(®) technique.

Design: A prospective, observational, cohort study was carried out.

Scope: Two medical-surgical Intensive Care Units.

[Utility of diffusion-weighted magnetic resonance imaging in severe focal traumatic brain injuries].

Objective: To describe the apparent diffusion coefficient (ADC) in a series of severe traumatic brain injuries, their clinical and outcome features, and possible implications.

Design: A descriptive, observational case-series study was carried out.

Patients And Interventions: Patients with severe traumatic brain injuries (TBIs) admitted to the ICU were subjected to MRI study using a 1.

[Is the permanent pacemaker implant more efficient in level 1 hospital?].

Objective: To determine if permanent pacemaker implants (PPM) interventions and change of generator are more efficient in small hospitals.

Design: A cost-effective analysis and retrospective, cross-sectional and observational study of diagnostic related groups (DRG).

Setting: The data was obtained from the national Minimum Basic Data Set (MBDS) for the year 2007 provided by the Health Ministry.