46 results match your criteria: "Hospital San Javier[Affiliation]"

Objectives: Bacterial infections are important causes of death. Some reports have shown that the COVID-19 pandemic may have had an impact on drug resistance. The objective of this work was to compare the resistance profiles between 2019 and 2020 in the emergency department, non-intensive care units (ICU), and ICU areas in Mexican hospitals.

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Article Synopsis
  • Disorders of somatic mosaicism (DoSMs) are rare genetic conditions that occur due to changes in cells after fertilization, and current guidelines for genetic variant interpretation are not well-suited for these disorders.* -
  • The Brain Malformations Variant Curation Expert Panel (BMVCEP) has adapted existing guidelines for brain-related DoSMs, but their applicability to other DoSM types is limited.* -
  • Researchers at Washington University have made modifications to the BMVCEP framework to enhance variant classification for broader DoSMs, which could lead to more accurate diagnoses and better clinical care.*
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  • Short bowel syndrome is a rare condition with limited existing data, prompting a registry study in Latin America focused on chronic intestinal failure, analyzing various patient and clinical factors from specialized centers.
  • From May 2020 to July 2023, the study included 167 patients (115 adults and 52 children) across 20 centers, revealing key demographics, complications, and outcomes, with significant differences between adults and children in terms of etiology and follow-up results.
  • The findings aim to enhance understanding of intestinal failure in Latin America, serving as both a data repository and an educational resource for healthcare teams, while striving for international recognition of regional health challenges.
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Background: Many factors, such as religion, geography, and customs, influence end-of-life practices. This variability exists even between different physicians.

Objective: To observe and describe the end-of-life actions of patients in the intensive care unit (ICU) and document the variables that might influence decision-making at the end of life.

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Background: ICU nurses are most frequently at the patient's bedside, providing care for both patients and family members. They perform an essential role and are involved in decision-making. Despite this, research suggests that nurses have a limited role in the end-of-life decision-making process and are occasionally not involved.

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Liposarcomas are described as soft tissue sarcomas derived from adipose tissue. The finding of this tumor in the mandibular region is exceedingly rare. As of now, it has been described mainly in case reports and small series.

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Synovial sarcoma (SS) and solitary fibrous tumor (SFT) are entities with considerable morphological and immunohistochemical similarities that sometimes show a non-confirmatory profile (TLE1 negative, CD34 and focal or negative STAT6 and lack of specific fusion IHC markers), in which the utility ultrastructure is unknown. A cross-sectional, retrospective, analytical, nonexperimental study was carried out by the Department of Pathology of the National Cancer Institute of Mexico (INCan) e from January 1, 2009 to December 31, 2018. With 17 SFT cases with diffuse or focal CD34 and STAT6 positivity and 18 cases of SS with positive FISH molecular test t(X:18) breakapart were studied by electron microscopy of fresh glutaraldehyde fixed or paraffin-embedded tissue.

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[COVID-19 in transplant recipients: Multicentric report of Mexican experience].

Arch Cardiol Mex

September 2023

Departamento de Nefrología, Instituto Nacional de Cardiología Ignacio Chávez, Ciudad de México, México.

Background: Solid Organ Transplant recipients (SOTR) appear to be at particular high risk for critical COVID-19 due to immunosuppressive drugs and comorbidities. We report the first description of clinical course and short-term outcomes of kidney and liver transplant recipients with confirmed COVID-19 in Mexico. The objective of this paper was evaluate the clinical course of transplant patients with COVID-19 infection.

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Objectives: To determine whether air pollution or changes in SARS-CoV-2 lineages lead to an increase in mortality.

Methods: Descriptive statistics were used to calculate rates of infection (2020-2021). RT-PCR was used to compare viral loads from October 2020 to February 2021.

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During the COVID-19 pandemic, the high prevalence of comorbidities and the disparities between the public and private health subsystems in Mexico substantially contributed to the severe impact of the disease. The objective of this study was to evaluate and compare the risk factors at admission for in-hospital mortality of patients with COVID-19. A 2-year retrospective cohort study of hospitalized adult patients with COVID-19 pneumonia was conducted at a private tertiary care center.

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Introduction: Understanding how Mexicans behave during the pandemic could present a complete picture of the phenomenon in our country and provide better management of it.

Objective: This study aimed to analyze the Mexican population's behavior and preventive measures.

Methods: This was a cross-sectional study in which a total of 4,004 participants from the general population responded to the survey.

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Spinocerebellar ataxia type 10 (SCA10) is an autosomal-dominant disorder caused by an expanded pentanucleotide repeat in the gene. This repeat expansion, when fully penetrant, has a size of 850-4,500 repeats. It has been shown that the repeat composition can be a modifier of disease, e.

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Depression and anxiety are common after months of social isolation, and they can have a negative impact on anyone's quality of life if they are not treated promptly and appropriately. The aim of this study was to determine if the change to online modality courses and the presence of depression or anxiety symptoms during the COVID-19 pandemic was associated with a difference in the college student's academic achievement. This study was a cross-sectional survey in which we used the Patient Health Questionnaire-9 (PHQ-9) and the General Anxiety Disorder-7 (GAD-7).

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A Brief Review of Carbon Dots-Silica Nanoparticles Synthesis and their Potential Use as Biosensing and Theragnostic Applications.

Nanoscale Res Lett

June 2022

Onkogenetik/Mexicana de Investigación Y Biotectogía SA. de C.V., Av. Miguel Hidalgo y Costilla 1966, Guadalajara, Jalisco, México.

Carbon dots (CDs) are carbon nanoparticles with sizes below 10 nm and have attracted attention due to their relatively low toxicity, great biocompatibility, water solubility, facile synthesis, and exceptional photoluminescence properties. Accordingly, CDs have been widely exploited in different sensing and biomedical applications, for example, metal sensing, catalysis, biosensing, bioimaging, drug and gene delivery, and theragnostic applications. Similarly, the well-known properties of silica, such as facile surface functionalization, good biocompatibility, high surface area, and tunable pore volume, have allowed the loading of diverse inorganic and organic moieties and nanoparticles, creating complex hybrid nanostructures that exploit distinct properties (optical, magnetic, metallic, mesoporous, etc.

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Cardiac double-hit and triple-hit lymphomas (DHLs, THLs) are rare; in fact, studies examining both DHL and THL remain scarce. THL with cardiac involvement constitutes a rare disease with few cases reported so far. Thus, in this study, we report the case of a 67-year-old woman who presented with initial symptoms of pulmonary embolism.

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Article Synopsis
  • The study compares nurse involvement in end-of-life decision-making across 22 European ICUs from 1999 (ETHICUS I) to 2015 (ETHICUS II).
  • Data were collected through an international e-based questionnaire that focused on decision-making processes and the roles of nurses and physicians.
  • Results indicate a decline in discussions involving nurses and a need to enhance their participation in such decisions, particularly in southern Europe.
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  • - The study highlights a global concern: medical students often lack adequate nutrition education to meet the competencies and attitudes necessary for effective nutrition care as physicians.
  • - A panel of Latin American nutrition experts participated in a Delphi survey to identify and agree upon 130 essential nutrition competencies, categorized into four main areas: basic nutrition concepts, public nutrition, nutrition status and disease, and nutrition care processes.
  • - The research concludes that medical school curricula should incorporate these competencies to enhance health promotion, disease prevention, and treatment related to nutrition, ultimately improving healthcare outcomes.
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Background: The present retrospective study reviewed acute promyelocytic leukemia (APL) cases recorded in Mexico between January 2007 and January 2017. The primary objective of the study was to evaluate overall survival (OS) in Mexican patients with APL. Secondary objective was to evaluate the impact of induction treatment with different anthracyclines on OS, event-free survival (EFS) and complications in this patient population.

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Rationale: The gap between the nutrition education provided to medical students and the nutrition competences and attitudes needed for doctors to provide effective nutrition care is a global concern. The goal of this study was to investigate the curricular content on nutrition education in Latin American medical schools and to evaluate the self-perceived knowledge, attitudes, and barriers to nutrition practice of final-year medical students.

Methods: Eighty-five public and private medical schools from 17 Latin American countries were invited to participate in the study.

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Background: Patients admitted to the intensive care unit (ICU) experience sleep disruption caused by a variety of conditions, such as staff activities, alarms on monitors, and overall noise. In this study, we explored the relationship between noise and other factors associated with poor sleep quality in patients.

Methods: This was a prospective cohort study.

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Sarcoidosis of the Skull: A Systematic Review.

World Neurosurg

July 2020

Department of Pathology, Hospital San Javier, Guadalajara, Jalisco, Mexico.

Background: Lesions of the skull make up a small but important part of neurosurgical practice. Several systemic disorders may involve the cranial vault including neoplastic and non-neoplastic conditions. Sarcoidosis of the skull is a little-known cause of calvarial involvement that has been rarely reported in the literature.

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Background: Medical specialty is a critical choice in a physician's life because it determines their professional future and medical practice. While some are motivated to choose a specific specialty based on the monetary gain it can provide, others are inspired by seeing the work performed by a physician or by a patient's recovery. It is common to stereotype doctors' personalities by their specialty.

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Recognition of Brain Metastases Using Gadolinium-Enhanced SWI MRI: Proof-of-Concept Study.

Front Neurol

February 2020

Department of Neurology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.

SWI MRI, a T2-dominant MRI sequence with T1 effect, uses intrinsic structural susceptibility to create enhancement among brain structures. We evaluated whether gadolinium-enhanced SWI (SWI-Gd) improves brain metastasis detection in combination with other MRI sequences. MRI images of 24 patients (46 studies) were prospectively acquired using a 1.

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