[Efficacy of single-dose preoperative tranexamic acid to prevent blood loss in total hip and knee joint replacement].

Introduction: transfusion-related complications are a major concern for surgeons performing total hip and knee arthroplasty (THA and TKA). Several strategies have been implemented to reduce transfusion rates, including the use of tranexamic acid (TXA), whose optimal dosage remains a matter of debate.

Objective: to evaluate the efficacy and safety of a single pre-surgical dose of TXA in reducing blood loss in THA and TKA.

Pre-surgical Embolization of Meningiomas: Analysis of Safety and Efficacy in a Mexican National Center And Proposal for a Classification of Preoperative Embolization of Meningiomas Based on Embolic Agent Penetration.

Introduction: Meningiomas are the most common primary central nervous system tumors, often requiring surgical resection. Presurgical embolization (PSE) is used to reduce intraoperative bleeding, although its effectiveness varies. This study evaluates the safety and efficacy of PSE using ethyl-vinyl alcohol (EVOH) in meningioma surgeries.

Impact of Wood Smoke Exposure on Aortic Valve Mineralization: Microvesicles as Mineral Conveyors in Patients with Coronary Stenosis.

Aortic valve calcification results from degenerative processes associated with several pathologies. These processes are influenced by age, chronic inflammation, and high concentrations of phosphate ions in the plasma, which contribute to induce mineralization in the aortic valve and deterioration of cardiovascular health. Environmental factors, such as wood smoke that emits harmful and carcinogenic pollutants, carbon monoxide (CO), and nitrogen oxide (NO), as well as other reactive compounds may also be implicated.

Gastroduodenal Obstruction Due to Bouveret's Syndrome: A Case Report.

Bouveret's syndrome is a rare disorder that causes upper gastrointestinal obstruction, typically in elderly patients with a history of chronic cholelithiasis. We present an unusual case of a 58-year-old woman with untreated vesicular lithiasis who developed Bouveret's syndrome. She presented with severe abdominal pain, nausea, vomiting, and abdominal distension.

Splenic Artery Pseudoaneurysm as a Complication of Chronic Pancreatitis.

Splenic artery pseudoaneurysms represent one of the most feared vascular complications of chronic pancreatitis. Sectional imaging studies such as computed tomography represent the first-line diagnostic tool for this pathology, being found as an incidental finding in patients with risk factors. We report the case of a splenic artery pseudoaneurysm in a 55-year-old patient diagnosed with chronic pancreatitis.

A worldwide assessment of the mechanical ventilation in patients with acute exacerbations of chronic obstructive pulmonary disease. Analysis of the VENTILAGROUP over time. A retrospective, multicenter study.

Background: The trend over time and across different geographical areas of outcomes and management with noninvasive ventilation or invasive mechanical ventilation in patients admitted for acute exacerbations of chronic obstructive pulmonary disease and treated with ventilatory support is unknown. The purpose of this study was to describe outcomes and identify variables associated with survival for patients admitted to an intensive care unit (ICU) with acute exacerbation of chronic obstructive pulmonary disease [aeCOPD] who received noninvasive or invasive mechanical ventilation worldwide.

Methods: Retrospective, multi-national, and multicenter studies, including four observational cohort studies, were carried out in 1998, 2004, 2010, and 2016 for the VENTILAGROUP following the same methodology.

Dermatological complications due to post‑COVID‑19 syndrome: A systematic review.

Almost 20% of patients affected by COVID-19 develop dermatological symptoms after recovery. This condition is termed as post-COVID-19 syndrome and is characterized by a state of hyperinflammation, as well as deregulations in the humoral response of CD8 T-cells. Since there is no specific treatment for these injuries, the treatment of choice depends on the symptoms; thus, it is essential to provide a description of the type and nature of the injuries presented.

Real-world data on the clinical features, therapy patterns, and outcomes of older adults with diffuse large B-cell lymphoma in Latin America: A study from the Grupo de Estudio Latinoamericano de Linfoproliferativos (GELL).

Introduction: Diffuse large B-cell lymphoma (DLBCL) is the most common type of B-cell lymphoma, predominantly afflicting older adults. There remains a notable absence of data regarding DLBCL in older adults in Latin America.

Materials And Methods: We conducted a retrospective analysis of 608 newly diagnosed Latin American patients with DLBCL aged ≥65 years.

No More High Notes: A Sequel of Spontaneous Laryngeal Rupture.

Spontaneous laryngeal rupture is an unusual event, typically caused by a sudden increase in barometric pressure and biomechanical forces within the laryngotracheal complex. Triggers often include actions such as coughing, sneezing, or violent retching. Given the delicate structures involved in this region, careful assessment is essential to ensure proper management and prevent complications.

Unmasking Tinea Incognito: Case Study, Insights Into the Pathogenesis, and Recommendations.

Tinea incognito (TI) is a dermatophyte infection that often presents atypically due to the inappropriate use of corticosteroids or other immunosuppressive treatments, complicating its diagnosis and management. This case report describes a 29-year-old American Indian (Maya) female from Yucatán, Mexico, initially diagnosed with inverse psoriasis and treated with topical corticosteroids. Over several months, her condition deteriorated, with lesions spreading and worsening, ultimately revealing TI.

Benralizumab: Effectiveness in Patients with Uncontrolled Severe Eosinophilic Asthma at 6 and 12 Months at a Third-Level Care Hospital. Capacity for ICS-LABA Therapy Reduction.

Background: Asthma is a health condition with worldwide relevance, evaluated based on the necessary treatment to control symptoms and exacerbations. Severe asthma is uncontrolled despite high doses of ICS-LABA and treatment for triggering factors. Severe eosinophilic asthma is characterized by an increase in eosinophils in the peripheral circulation, walls, and passages of the respiratory tract.

Rheumatic Multivalvular Disease in Older Patients: Late Diagnosis and Treatment After Complications.

Rheumatic multiple valvular heart disease remains undertreated and underestimated in older patients; many are unaware of their diagnosis until they experience complications. This case series presents 3 older patients with undiagnosed rheumatic multiple valvular heart disease who presented with complications, describing their valvular assessment and therapeutic outcomes.

Bouveret's Syndrome: A Diagnostic and Therapeutic Approach to an Unusual Complication of Cholelithiasis.

Bouveret's syndrome is a rare form of bowel obstruction caused by the impaction of a large gallstone through a cholecystoduodenal fistula, leading to gastric outlet obstruction. This article aims to highlight the clinical presentation and management of this syndrome, given its low incidence and high mortality rate of 12% to 30%. We present the case of an 83-year-old patient with a history of diabetes and hypertension who presented with abdominal pain, distension, and vomiting.

Epidemiology of reinfections by SARS-CoV-2 variants during the third and fourth waves of the COVID-19 pandemic.

Introduction: The coronavirus disease 2019 (COVID-19) pandemic is a global health concern and has persisted through the emergence of variants that have caused subsequent waves of COVID-19 due to the high dispersion and contagiousness of the virus. The aim of this work was to analyze the epidemiology of the cases of reinfection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants during the third and fourth wave of the COVID-19 pandemic at the Hospital Juárez de México (HJM).

Methodology: A prospective study of the cases of SARS-CoV-2 reinfection, variants detected, symptoms, and associated comorbidities was carried out on 1,347 patients who attended the HJM from September 2021 to July 2022.

Surgical Management of Acute Forearm Compartment Syndrome Due to Suspected Edematous Cutaneous Loxoscelism.

BACKGROUND Compartment syndrome of the forearm has been associated with a variety of etiologies, including fractures, snake bites, complications of certain infections, and, very rarely, spider bites. Loxoscelism is the venom-related clinical manifestation of the bite of spiders of the genus Loxosceles, also called brown or fiddler (violinist) spiders. It manifests locally/regionally with pain, erythema, and edema, with subsequent necrotic plaque formation at the site of the bite.

Agmatine: An Emerging Approach for Neuroprotection in Recurrent Ischemic Stroke Events in a Murine Model.

This study investigates the effect of agmatine on reducing mortality, neurobehavioral alterations, infarct size, and expression of pro-inflammatory cytokines in mice subjected to bilateral carotid thrombosis. Under pentobarbital anesthesia, the left common carotid artery was exposed to 6% FeCl. Thirty-two days later, the same procedure was performed on the right common carotid artery.

Effectiveness of robotic metabolic and bariatric surgery in patients with BMI ≥ 50-59.9 and BMI ≥ 60 for the treatment of severe obesity in a national medical center in Mexico.

Introduction: Obesity is a global health issue that significantly increases morbidity and mortality when the Body Mass Index (BMI) reaches values ≥ 50. While metabolic and bariatric surgery (MBS) is the most effective treatment for severe obesity, it carries risks. Robotic surgery is promising but not extensively studied in Mexico, which presents an opportunity for research at a National Hospital with an academic program.

Latissimus Dorsi Musculocutaneous Flap as a Therapeutic Option in Breast Reconstructive Surgery: A Case Report.

In plastic surgery, the reconstructive ladder is a systematic approach used to guide the planning and execution of reconstructive procedures. The use of autologous tissues is preferred in the breast reconstruction process due to the multiple advantages they offer. The latissimus dorsi musculocutaneous flap has been the therapeutic option of choice in these cases, replacing other surgical techniques because of the high adaptability and low complication rates.

Socioeconomic factors and COVID-19 mortality in immune-mediated rheumatic diseases patients: regional analysis from Argentina, Mexico and Brazil.

Background: SARS-CoV-2 infection has become a major international issue, not only from a medical point of view, but also social, economic and political. Most of the available information comes from the United States, Europe, and China, where the population and the socioeconomic status are very different from Latin American countries. This study evaluates the effect of regional socioeconomic characteristics on mortality due SARS-CoV-2 infection in patients with immune-mediated rheumatic diseases (IMRD) from Argentina, Mexico and Brazil.

Endovascular embolization combined with anterior cervical corpectomy for treatment of cervical spinal dural arteriovenous fistula.

Background: The two main treatments for spinal dural arteriovenous fistula (SDAVF) include microsurgical occlusion or endovascular embolization (i.e., the latter alone has high recurrence rates).

Acute Abdominal Pain Secondary to Omental Infarction: A Case Report.

Omental infarction is a rare but threatening cause of acute abdomen. The preoperative diagnosis is challenging due to its infrequent nature. It poses nonspecific abdominal signs that can be easily mistaken for other more common intra-abdominal pathologies.