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Prostate stem cell antigen - novel biomarker and therapeutic target?
Expert Rev Anticancer Ther
January 2014
Department of Urology, Hospital Prof. Doutor Fernando Fonseca and Hospital CUF Descobertas, Lisbon, Portugal.
Prostate stem cell antigen gene was originally identified through an analysis of genes upregulated in the human prostate cancer LAPC-4 xenograft model. PSCA was named inaccurately since it is not a marker for a stem cell population nor is it exclusively expressed in the prostate. The function of PSCA in normal cellular processes or carcinogenesis is currently unknown.
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