Age of onset of recurrent respiratory papillomatosis: a distribution analysis.

Objective: Distribution of age of onset of recurrent respiratory papillomatosis (RRP) is generally described to be bimodal, with peaks at approximately 5 years and 30 years. This assumption has never been scientifically confirmed, and authors tend to refer to an article that does not describe distribution. Knowledge of the distribution of age of onset is important for virological and epidemiological comprehension.

Detection of inheritance pattern in thirty-three Mexican males with chronic granulomatous disease through 123 dihydrorhodamine assay.

Background: There are two inheritance patterns, the X-linked recessive (XL) pattern and the autosomal recessive pattern. There is no information on the predominant inheritance pattern of male patients with chronic granulomatous disease (CGD) in Mexico.

Objective: The aim of this study was to determine the inheritance pattern in a cohort of Mexican male patients with CGD by means of the detection of an XL status carrier among their female relatives, and to describe the frequency of discoid lupus (DL) among carriers.

Fractional exhaled nitric oxide has a good correlation with asthma control and lung function in latino children with asthma.

Background: Although the measurement of fractional exhaled nitric oxide (FE(NO)) has been recommended for observational studies and clinical trials of asthma, FE(NO) has not been examined in studies of childhood asthma in Latin America,

Objective: To examine the relationship between FE(NO) and indicators of disease control or severity [asthma control test/childhood asthma control test (ACT/C-ACT), lung function, and exercise challenge test (ECT)] in Mexican children with persistent asthma,

Methods: Children (6-18 years of age) with persistent asthma were consecutively recruited in a tertiary asthma clinic and divided into two groups, e.g. FE(NO) < 20 parts per billion (ppb) and ≥20 ppb.

[Is the Down syndrome a primary immunodeficiency?].

Down syndrome is associated with changes characteristic of primary immunodeficiencies, such as susceptibility to infection, autoimmunity and malignancy risk. However, it is not considered a primary immunodeficiency but rather a syndromatic deficiency, due to the relevance of the characteristic neurological delay. This article presents some arguments that consider Down syndrome as a primary immunodeficiency.