Desmoplastic cutaneous leiomyosarcoma: case report and review of the literature.

We report the case of a 51-year-old man with an asymptomatic indurated plaque on the chest wall that was surgically excised and submitted for histopathological examination. Microscopically, the dermis was occupied by a neoplastic process with spindle-shaped cells arranged in longitudinal fascicles with cytologic atypia; the abundant sclerotic stroma was composed of hyaline material. Tumoral cells showed immunohistochemical reactivity to smooth muscle markers.