21 results match your criteria: "Hospital General Regional 46[Affiliation]"
Cir Cir
October 2024
Departamento de Otorrinolaringología y Cirugía de Cabeza y Cuello, Centro Médico Nacional de Occidente, IMSS. Guadalajara, Jalisco, México.
Introduction: Lipomas are the most common tumors of mesenchymal origin throughout the body. Although they have low incidence in the oral cavity, they surgical approach can be challenging.
Case Report: 10-year-old male with a giant lipoma in the buccal and masticator space, an intraoral surgical approach was chosen using by modifying trident technique of Ramírez-Oropeza.
Kidney Int Rep
July 2024
Department of Community Health, Research on Ethics, Aging, and Community Health (REACH Lab), Tufts University, Medford, Massachusetts, USA.
Nephron
July 2024
Department of Nephrology and Hypertension, IIS-Fundacion Jimenez Diaz UAM, Madrid, Spain.
Diabetic kidney disease is the most common driver of chronic kidney disease (CKD)-associated mortality and kidney replacement therapy. Despite recent therapeutic advances (sodium glucose co-transporter 2 [SGLT2] inhibitors, finerenone), the residual kidney and mortality risk remains high for patients already diagnosed of having CKD (i.e.
View Article and Find Full Text PDFNephron
August 2024
Nephrology Department, Instituto Nacional de Cardiologia, Ciudad de Mexico, Mexico City, Mexico.
Introduction: The percutaneous kidney biopsy (PKB) is an essential tool in nephrology; small kidney size has been a relative contraindication to PKB and there is limited data on the safety and utility of performing PKB in this setting. Our aim was to describe the complications of PKB in small kidneys and to assess if kidney biopsy results have an impact on medical decisions and outcomes.
Methods: This was a retrospective, descriptive, and observational study.
Int J Mol Sci
January 2024
División de Genética, Centro de Investigación Biomédica de Occidente, Instituto Mexicano del Seguro Social, Guadalajara 44340, Mexico.
Systemic lupus erythematosus (SLE) is a multisystem disease considered a prototype of the main autoimmune disease and presents serious complications, such as lupus nephritis (LN), which generates a significant impact on morbidity and mortality. The gene encodes the osteopontin (OPN) protein, which plays a crucial role in the regulation of inflammation and immunity. The variants rs1126616 and rs9138 of this gene have been associated with the inflammatory response.
View Article and Find Full Text PDFCurr Hypertens Rep
March 2024
Division of Nephrology and Hypertension, Department of Medicine, University of Mississippi Medical Center, 2500 N State Street, Jackson, MS, USA.
Purpose Of Review: This review aims to explore the underlying mechanisms that lead to hypertension in glomerular diseases and the advancements in treatment strategies and to provide clinicians with valuable insights into the pathophysiological mechanisms and evidence-based therapeutic approaches for managing hypertension in patients with glomerular diseases.
Recent Findings: In recent years, there have been remarkable advancements in our understanding of the immune and non-immune mechanisms that are involved in the pathogenesis of hypertension in glomerular diseases. Furthermore, this review will encompass the latest data on management strategies, including RAAS inhibition, endothelin receptor blockers, SGLT2 inhibitors, and immune-based therapies.
Medicine (Baltimore)
February 2022
Departamento de Fisiología, Instituto de Investigación en Ciencias Biomédicas, Programa de Doctorado en Salud Publica, Departamento de Salud Publica, Programa de Doctorado en Farmacología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, Jalisco, México.
Irisin stimulates osteoblast differentiation increasing bone mass a decreasing in irisin levels might contribute to osteoporotic fractures in inflammatory diseases. To date, there is controverted whether irisin levels are associated with osteoporotic fractures in rheumatoid arthritis (RA). Therefore, we evaluate the association of serum irisin with osteoporotic Vertebral Fractures (VFs) in women with RA.
View Article and Find Full Text PDFBiomed Res Int
October 2021
Programa de Doctorado en Ciencias de la Salud Pública, Departamento de Salud Pública, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, 44340 Guadalajara, JAL, Mexico.
Background: Fracture risk assessment tool (FRAX) index was developed for estimating of the 10-year risk of major or hip osteoporotic fracture. To date, there is insufficient information regarding the correlation between FRAX and serum bone turnover markers (BTMs), such as soluble ligand of receptor activator of nuclear factor-B (sRANKL), osteoprotegerin (OPG), and other molecules related with secondary osteoporosis in rheumatoid arthritis (RA). Therefore, this study is aimed at assessing the correlation between the FRAX and serum levels of sRANKL, OPG, sRANKL/OPG ratio, Dickkopf-1 (DKK-1), and sclerostin (SOST) in RA.
View Article and Find Full Text PDFSci Rep
April 2021
Programa de Doctorado and Coordinacion del Programa de Doctorado en Salud Publica, Departamento de Salud Publica, Instituto Regional de Investigacion en Salud Publica, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico.
Adipokines, especially chemerin, can interact with cytokines and other molecules in inflammation. To date, there is insufficient information regarding a possible correlation between functional disability and chemerin and other pro-inflammatory molecules in rheumatoid arthritis (RA). To identify the association of functional disability with serum chemerin and other pro-inflammatory molecules, including other adipokines, cytokines and E-selectin, in patients with RA.
View Article and Find Full Text PDFGac Med Mex
January 2020
Instituto Nacional de Cardiología "Ignacio Chávez", Departamento de Endocrinología, Ciudad de México, México.
Introduction: Multi-frequency bio-impedance analysis (BIA) accurately evaluates body composition.
Objective: To assess nutritional status and its relationship with body mass index (BMI) or with BIA-obtained phase angle in patients with end-stage renal disease (ESRD) on hemodialysis.
Method: BMI, BIA and dialysis malnutrition score (DMS) were assessed in 99 patients on hemodialysis (43.
J Clin Lab Anal
February 2019
Laboratorio de Inmunología, Departamento de Fisiología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, Jalisco, México.
Introduction: Diabetic Nephropathy (DN) is the main cause of chronic kidney disease (CKD) in diabetic patients. An IL-10 imbalance could be related to renal hypertrophy and trigger to nephropathy. Three promoter polymorphisms (-1082G>A, -819C>T, and -592C>A) at IL10 gene have been associated with changes in the IL-10 expression and DN susceptibility.
View Article and Find Full Text PDFReumatol Clin (Engl Ed)
June 2019
Hospital Ángeles del Pedregal, Ciudad de México, México. Electronic address:
There are national and international clinical practice guidelines for systemic lupus erythematosus treatment. Nonetheless, most of them are not designed for the Mexican population or are devoted only to the treatment of certain disease manifestations, like lupus nephritis, or are designed for some physiological state like pregnancy. The Mexican College of Rheumatology aimed to create clinical practice guidelines that included the majority of the manifestations of systemic lupus erythematosus, and also incorporated guidelines in controversial situations like vaccination and the perioperative period.
View Article and Find Full Text PDFSemin Arthritis Rheum
December 2018
Unidad de Investigación en Enfermedades Cronico-Degenerativas, Guadalajara, México; Universidad Autonoma de Guadalajara, Guadalajara, México. Electronic address:
Objective: To assess trends in the length and readability of informed consent forms (ICFs) for industry-sponsored multinational clinical trials (RCTs) in rheumatology over a 17-year period. Additionally, to assess the health literacy (HL) and perceptions of ICFs among participants of current RCTs.
Methods: The readability of ICFs conducted at an outpatient rheumatology clinic between 1999 and 2016 were assessed using the INFLESZ scale.
Acta Ortop Mex
April 2019
Expresidente del Colegio de Medicina Interna de México. México.
In the degradation of articular cartilage, functional limitation and pain cardinal signs of osteoarthritis underlies, as a central factor, the quantitative and qualitative alteration of hyaluronic acid, the main component of synovial fluid and cartilage, in a pathophysiological process influenced by a wide variety of risk factors whose impact complicates the disease and radically reduces the quality of life of the patient. Conventional pharmacological management for osteoarthritis is often insufficient. Fortunately, in our days, there are viscosupplements capable of improving, replacing and promoting the endogenous production of degraded hyaluronic acid in osteoarthritis.
View Article and Find Full Text PDFArthritis Rheumatol
November 2015
Hospital General Regional 46, Instituto Mexicano del Seguro Social, Guadalajara, Mexico.
Objective: Although blood bank-based studies have shown that rheumatoid arthritis (RA)-related autoantibodies are present before the onset of RA, information on their positive predictive value (PPV) for development of RA in healthy individuals is scarce. This study was undertaken to assess the 5-year PPV of serum IgM rheumatoid factor (IgM-RF) and anti-cyclic citrullinated peptide (anti-CCP) for the development of RA among healthy relatives of patients with RA.
Methods: Healthy relatives of RA patients were invited to participate in a cohort study.
J Surg Res
December 2014
Department of Surgical Oncology, Hospital General Regional 46, IMSS, Guadalajara, Jalisco, México.
Background: The main postoperative complications after tonsillectomy are due to bleeding, and effective hemostasis may lead to a reduction of overall postoperative morbidity. This study was undertaken to determine the efficacy and safety of a novel kaolin-based hemostatic dressing in tonsillectomy.
Methods: A pilot, single-blind, open label study was performed in patients aged 3-20 y with history of chronic or hypertrophic tonsillitis.
Rev Invest Clin
March 2013
Instituto Nacional de Cancerología (INCan).
Rev Med Inst Mex Seguro Soc
November 2014
Coordinación de Educación e Investigación en Salud, Hospital General Regional 46, Instituto Mexicano del Seguro Social, Guadalajara, Jalisco, Mexico.
Background: burnout and quality of life are poorly studied phenomena in postgraduate students, and its effects are unknown. The aim was to investigate the relationship between quality of life and burnout in medical residents.
Methods: a longitudinal study was performed.
Clin Dysmorphol
January 2011
Instituto de Genetica Humana 'Dr Enrique Corona Rivera' Instituto de Enfermedades Cronico-Degenerativas, Departamento de Biologia Molecular y Genomica, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara Hospital de Especialidades, CMNO Division de Medicina Molecular, CIBO, CMNO, IMSS Hospital General Regional 46 Hospital General Regional 45, IMSS, Guadalajara, Jalisco, Mexico Instituto de Genetica de la Facultad de Ciencias Medicas de la Universidad Nacional de Cuyo, Mendoza, Argentina.
Three female patients with Cantu syndrome were studied, two of whom were adults presenting with the complication of lymphoedema, as described earlier in a male patient with this syndrome. The aim of this study is to report the clinical characteristics of these three new cases and to emphasize that lymphoedema, as observed in two of the patients described here, has been observed in 11.5% of patients with Cantu syndrome and that heterochromia iridis, observed in one patient, is probably a new feature of this condition.
View Article and Find Full Text PDFRev Med Inst Mex Seguro Soc
August 2010
Hospital General Regional 46, Instituto Mexicano del Seguro Social, Guadalajara, Jalisco, México.
Background: Kawasaki disease (EK) is frequently identified in pediatric patients. It affects principally the coronary arteries, causing aneurysms, ischemic heart disease and sudden death. The opportune diagnosis and its early treatment avoid these complications.
View Article and Find Full Text PDFClin Dysmorphol
April 2004
Divisiones de Medicina Molecular y Genetica, Centro de Investigacion Biomedica de Occidente Servicio de Otorrinolaringologia, Hospital de Especialidades Cirugia Pediatrica, Hospital de Pediatria, CMNO, IMSS Hospital General Regional 46, IMSS Doctorado de Genetica Humana, CUCS, Universidad de Guadalajara CIATEJ (CONACYT), Guadalajara, Jalisco Departamento de Inmunobiologia Molecular, Centro de Investigación Biomédica, Facultad de Medicina, Universidad Autonoma de Coahuila. Torreon, Coahuila, Mexico.
Myhre syndrome is a rare disorder characterized by low birthweight, short stature, mental retardation, facial dysmorphism (blepharophimosis, midfacial hypoplasia, prognathism), heart anomalies, muscle hypertrophy, decreased joint mobility and deafness. To date 11 male cases and only one female case have been reported. This paper describes the second female case and compares the clinical and radiological findings between female and male patients.
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