788 results match your criteria: "Hospital General Regional[Affiliation]"

[Prevalence of bronchiectasis in patients with inborn errors of immunity].

Rev Alerg Mex

December 2024

Pediatra con subespecialidad en Alergia e Inmunología Clínica; jefe del servicio y profesor titular de la especialidad de Alergia e Inmunología Clínica, Unidad Médica de Alta Especialidad, Hospital de Especialidades, Centro Médico Nacional de Occidente, Instituto Mexicano del Seguro Social, Guadalajara, Jalisco.

Objective: To establish the prevalence of bronchiectasis, correlate the IgG IV or SC immunoglobulin dose and serum IgG levels with the total Bhalla score and the severity of bronchiectasis and associate serum IgG levels with the development of pulmonary infectious processes in patients with diagnosis of innate errors of immunity.

Methods: A descriptive, observational, cross-sectional study with patients over 18 years of age diagnosed with IBD. Clinical records and computed axial tomography were reviewed.

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Antiplatelet, Anticoagulant, and Fibrinolytic Activity of Orchids: A Review.

Molecules

December 2024

CONAHCYT-Centro Interdisciplinario de Investigación para el Desarrollo Integral Regional Unidad Oaxaca, Instituto Politécnico Nacional, Santa Cruz Xoxocotlán 71233, Oaxaca, Mexico.

Thrombosis is the occlusion of a blood vessel and is responsible for the highest number of deaths worldwide. Its treatment comprises the use of anticoagulants, antiplatelets, and thrombolytics. Although many antithrombotic drugs are currently available, none is completely effective and safe.

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Meta-Analysis of Seroprevalence and Prevalence of Influenza A Viruses (Subtypes H3N2, H3N8, and H1N1) in Dogs.

Animals (Basel)

December 2024

Departamento de Medicina y Zootecnia de Cerdos, Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de México, Ciudad de México 04510, Mexico.

Influenza A is a zoonotic disease that affects dogs, pigs, horses, poultry, and birds. In this report, a meta-analysis according to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) was conducted. Studies of influenza A viruses in dogs providing prevalence or seroprevalence in any location worldwide were included.

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Article Synopsis
  • Adverse drug reactions (ADRs) can be classified into Type A (pharmacokinetics-related) and Type B (immune response-related), with Type B reactions being less well-defined and often categorized into immediate and delayed types.
  • This review aims to explore the immunological mechanisms behind delayed hypersensitivity reactions to medications, highlighting their complexities.
  • Findings discuss the classification, clinical signs, diagnosis, treatment plans, and overall prognosis of delayed hypersensitivity, emphasizing the need for prompt, tailored approaches by healthcare professionals.
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Background: Acute hemorrhagic leukoencephalitis (AHLE) or Weston-Hurst syndrome is a rare and severe variant of acute disseminated encephalomyelitis (ADEM). It causes fulminant hemorrhagic demyelination of the central nervous system, and has high mortality and morbidity. Due to the increase in cases and to its high rate of mortality, we decided to make a series of cases and a review of the disease.

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In 2018, the WHO published a methodology for conducting a point prevalence survey (PPS) of antibiotic use in hospitals. The aim of this study is to report the use of antibiotics in six second-level hospitals in Mexico using this methodology. Methods: A multicenter cross-sectional study based on the 2021-2023 adaptation for Latin American hospitals was conducted in internal medicine, surgery, intensive care unit (ICU), obstetrics and gynecology and pediatrics departments of the IMSS in the western region of the state of Mexico.

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Pneumopericardium is an unusual condition defined by the presence of gas into the pericardial sac. Gastric perforation into pericardium is a complication of gastric ulcer with high mortality. In this clinical case, we describe the condition of a male with a silent gastric ulcer, which penetrated into the pericardium, developing pneumopericardium and purulent pericarditis as a complication.

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A ten-year experience with the diagnosis of von Willebrand disease in Mexico based on a cost-effective strategy.

Arch Med Res

November 2024

Unidad de Investigacion Médica en Trombosis, Hemostasia y Aterogénesis, Instituto Mexicano del Seguro Social, Mexico City, Mexico. Electronic address:

Background: Von Willebrand disease (VWD), is the most common inherited bleeding disorder worldwide, but its diagnosis is complicated, expensive, and poorly evaluated in several countries.

Objective: To report our long-term experience with the diagnosis of VWD based on a cost-effective strategy.

Methods: We studied 802 Mexican patients, men and women, children, and adults, with clinical suspicion of VWD.

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[Arrhythmia as the first symptom of neonatal cardiac tumors: Case report].

Rev Med Inst Mex Seguro Soc

November 2024

Instituto Mexicano del Seguro Social, Hospital General Regional No. 17, Servicio de Cardiología Pediátrica. Cancún, Quintana Roo, México.

Background: Neonatal cardiac tumors are a rare pathology, with an approximate incidence of 0.017% in autopsies and 0.31% in obstetric echographies.

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[Characteristics of melanoma in Mexicans seen at "La Raza" National Medical Center].

Rev Med Inst Mex Seguro Soc

November 2024

Universidad Nacional Autónoma de México, Facultad de Medicina, División de Investigación. Ciudad de México, México.

Background: Melanoma is the third most common type of skin cancer in Mexico and represents 75% of skin cancer deaths. Dermoscopy is a diagnostic tool that increases early detection of melanoma compared to naked eye examination.

Objective: The aim of this study was to describe the clinical, dermoscopic and histological characteristics of patients with a confirmed diagnosis of cutaneous melanoma treated at the "La Raza" National Medical Center.

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[HIV mortality trends in Mexico, 2000-2022].

Rev Med Inst Mex Seguro Soc

November 2024

Instituto Mexicano del Seguro Social, Hospital General Regional 1 "Dr. Carlos MacGregor Sánchez Navarro", Unidad de Investigación en Epidemiología Clínica. Ciudad de México, México.

Background: About 39 million people are living with HIV worldwide, 62% of people living with HIV receive antiretroviral therapy. The combination of ART has allowed suppression of viral replication and disease progression, decreasing mortality.

Objective: To analyze HIV trends in Mexico during the period 2000-2022.

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[Aortic dissection: A challenge for the emergency medicine? A case report].

Rev Med Inst Mex Seguro Soc

July 2024

1Instituto Mexicano del Seguro Social, Hospital General Regional No.1 "Carlos McGregor Sánchez Navarro", Servicio de Urgencias. Ciudad de México, México.

Article Synopsis
  • Acute aortic syndrome, first described in 2001, includes four conditions characterized by severe aortic pain, with aortic dissection being the most common and serious manifestation.
  • A case involves a 50-year-old man with a history of high blood pressure and chronic kidney disease who presented with abdominal pain, highlighting the importance of recognizing symptoms.
  • Accurate and timely diagnosis of acute aortic syndrome in the emergency department is crucial because the risk of mortality increases significantly with each hour that passes without treatment.
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Background: Lifestyle changes in adolescents are characterized by a poor diet which means rich in fat and cholesterol, and it is associated with the development of dyslipidemia, which is considered one of the main risk factors for cardiovascular disease in adulthood.

Objective: To identify the association between risk eating habits and the presence of dyslipidemia in adolescents at the primary health care level.

Material And Methods: Cross-sectional, analytical, and retrospective study, which included adolescents aged 10-17 years.

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[Broken spinal needle: Clinical case and a brief review of the literature].

Rev Med Inst Mex Seguro Soc

May 2024

Instituto Mexicano del Seguro Social, Hospital General de Zona No. 3, Servicio de Anestesiología. San Juan del Río, Querétaro, México.

Background: Spinal anesthesia can present various complications, one of which is the breakage of a spinal needle within the intrathecal space, which is one of the least frequent complications and it may be serious. A case of spinal needle breakage is presented, pointing out its risk factors and recommendations to reduce it.

Clinical Case: 5-year-old female patient, who was scheduled for removal of translocated intrauterine device causing chronic pain.

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Article Synopsis
  • The update of the Mexican Guidelines for the Treatment of Systemic Lupus Erythematosus has been developed with input from various experts across the country.
  • The new guidelines follow the GRADE system, which helps in evaluating the quality of evidence for healthcare recommendations.
  • Key new topics included in the update are vaccines, pregnancy, and cardiovascular risk, which were not addressed in the previous guidelines from 2017.
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Background The timely identification of colorectal anastomotic leakage (CAL) is still a significant challenge, and identifying reliable markers is essential to minimize patient morbidity and mortality. While procalcitonin (PCT) has shown promise as a biomarker for CAL, its effectiveness must be specifically evaluated in colorectal cancer patients. This systematic review and meta-analysis sought to assess the mean differences in PCT levels between individuals with and without CAL who underwent colorectal surgery for colorectal cancer.

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Unlabelled: Chronic Obstructive Pulmonary Disease (COPD) is a disease characterized by local and systemic inflammation independently of the risk factor; during the exacerbations, such inflammation is accentuated and amplified. A practical inflammatory marker and one with an applicable predictive value in the follow-up has been sought. FeNO has shown an excellent performance in that respect within the context of asthma and has also been studied in tobacco-smoke COPD (COPD-TS).

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Article Synopsis
  • Gastrointestinal stromal tumors (GIST) are rare tumors affecting about 10 to 15 people per million, primarily found in the stomach and small intestine, and may present symptoms like nausea and abdominal fullness, although 30% are asymptomatic.
  • The standard treatment for GIST is surgical resection with negative margins.
  • A case report describes a 69-year-old woman who experienced severe digestive tract bleeding, leading to the discovery of a GIST in her jejunum during surgery.*
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Modified trident technique for surgical approach to facial lipoma.

Cir Cir

October 2024

Departamento de Otorrinolaringología y Cirugía de Cabeza y Cuello, Centro Médico Nacional de Occidente, IMSS. Guadalajara, Jalisco, México.

Introduction: Lipomas are the most common tumors of mesenchymal origin throughout the body. Although they have low incidence in the oral cavity, they surgical approach can be challenging.

Case Report: 10-year-old male with a giant lipoma in the buccal and masticator space, an intraoral surgical approach was chosen using by modifying trident technique of Ramírez-Oropeza.

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Background: Most individuals show immunity to SARS-CoV-2 from vaccination or infection, or both. We aimed to determine the safety and immunogenicity of an omicron-containing COVID-19 vaccine (mRNA-1273.222) in vaccine-naive adolescents who were SARS-CoV-2 positive.

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Effect of adequacy of empirical antibiotic therapy for hospital-acquired bloodstream infections on intensive care unit patient prognosis: a causal inference approach using data from the Eurobact2 study.

Clin Microbiol Infect

December 2024

OUTCOMEREA Research Group, Drancy, France; Institut National de la Santé et de la Recherche Medicale, Infection Antimicrobial Modelisation Evolution, U1137, Team Decision Science in Infectious Diseases, Paris, France; Assistance Publique Hôpitaux de Paris, Bichat hospital, Medical and infectious diseases ICU, F75018, Paris France. Electronic address:

Article Synopsis
  • Hospital-acquired bloodstream infections (HA-BSI) in ICU patients can be life-threatening, and this study aimed to see how early adequate antibiotic treatment affects 28-day mortality rates for patients who survive at least one day after infection onset.
  • Using data from a multicenter study with 2,418 patients, researchers found that those who received adequate treatment within 24 hours had a lower 28-day mortality rate (32.8%) compared to those who were inadequately treated (40%).
  • The study concluded that inadequate antibiotic therapy within 24 hours contributes significantly to 28-day mortality, indicating that quicker treatment could greatly improve patient outcomes in cases of HA-BSI.
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Objective: To address the current practice of liberating patients from invasive mechanical ventilation in pediatric intensive care units, with a focus on the use of standardized protocols, criteria, parameters, and indications for noninvasive respiratory support postextubation.

Methods: Electronic research was carried out from November 2021 to May 2022 in Ibero-American pediatric intensive care units. Physicians and respiratory therapists participated, with a single representative for each pediatric intensive care unit included.

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Objective: Determine the level of knowledge of mothers of children under 5 years of age about vaccination schedule.

Methods: Cross-sectional, observational, descriptive, and analytical study, carried out in the Family Medicine Unit 1 of Orizaba, Veracruz, in which two questionnaires were applied to mothers of children under 5 years of age, one prepared by PAHO that qualifies attitudes. of parents about vaccines, and another that evaluates knowledge of immunizations.

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