9 results match your criteria: "Hospital Egas Moniz - CHLO[Affiliation]"

Article Synopsis
  • Platelet transfusions are commonly administered in ICUs for patients with low platelet counts (thrombocytopenia), but the specific practices and their outcomes are not well-documented.
  • In a study of 504 ICU patients across Europe and the U.S., 20.8% received platelet transfusions, primarily using pooled products, with varying practices in dosage and volume across different countries.
  • The research found that while platelet transfusions are frequent, they provide limited increases in platelet counts, indicating potential inconsistencies in their effectiveness and administration practices.
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Article Synopsis
  • Thrombocytopenia, defined as a low platelet count, is a frequent issue in ICU patients and is linked to poorer health outcomes, including higher mortality rates.
  • A study involving 1166 ICU patients across 52 ICUs in 10 countries found that 43.2% had thrombocytopenia, with nearly one-quarter presenting with it upon admission.
  • Thrombocytopenia at ICU admission was statistically associated with increased 90-day mortality, and while 22.6% of those affected received platelet transfusions, the majority were given as a precautionary measure.
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Osteoarthritis (OA) is the most prevalent rheumatic disease and is a leading cause of decreased quality of life (QoL). The OA Quality of Life questionnaire (OAQoL) is an OA-specific patient-reported outcome measures. The aim of this study was to translate and validate the original UK English version of the Osteoarthritis Quality of Life (OAQoL) questionnaire into European Portuguese.

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Objectives: B-cell dysfunction and activation are thought to contribute to lymphoma development in HIV-positive people; however, the mechanisms are not well understood. We investigated levels of several markers of B-cell dysfunction [free light chain (FLC)-κ, FLC-λ, immunoglobulin G (IgG), IgA, IgM and IgD] prior to lymphoma diagnosis in HIV-positive people.

Methods: A nested matched case-control study was carried out within the EuroSIDA cohort, including 73 HIV-positive people with lymphoma and 143 HIV-positive lymphoma-free controls.

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Transmitted drug resistance in drug-naïve HIV-2 infected patients.

AIDS

June 2016

aDepartment of Infectious Diseases, Hospital Pedro Hispano - ULS, Matosinhos bDepartment of Infectious Diseases cDepartment of Infectious Diseases, Hospital Egas Moniz - CHLO, E.P.E., Lisboa dCiiEM - Centro de Investigação Interdisciplinar Egas Moniz, Almada, Portugal.

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Introduction: Low-level viraemia (LLV) is observed in some patients with HIV-1 infection on stable antiretroviral therapy (ART). The significance of these findings remains controversial as it conflicts with traditional optimal clinic outcome. This study aims to evaluate the effect of LLV on the establishment of virological failure (VF) and immune deterioration.

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