Basal cell carcinoma of the buccal mucosa in a patient with nevoid basal cell carcinoma syndrome.

Basal cell carcinoma (BCC) of the oral cavity is a controversial lesion with clinical and histopathologic features that overlap with those of peripheral ameloblastoma (PA). Ber-EP4, a cell surface glycoprotein preferentially expressed in BCC of the skin, has been suggested as a useful marker to support the diagnosis of oral BCC.This study presents a case of intraoral BCC arising in the anterior buccal mucosa of a patient with nevoid basal cell carcinoma syndrome (NBCCS), which represents a previously unreported clinical finding, to our knowledge.

Use of cone beam computed tomography in endodontics.

Cone Beam Computed Tomography (CBCT) is a diagnostic imaging modality that provides high-quality, accurate three-dimensional (3D) representations of the osseous elements of the maxillofacial skeleton. CBCT systems are available that provide small field of view images at low dose with sufficient spatial resolution for applications in endodontic diagnosis, treatment guidance, and posttreatment evaluation. This article provides a literature review and pictorial demonstration of CBCT as an imaging adjunct for endodontics.

Enhanced osteoblast function on ultraviolet light-treated zirconia.

Unlike titanium, surface roughening of zirconia for enhanced bone integration has been technically challenging. The photochemical reaction of semiconductor oxides, e.g.

How going digital will affect the dental office.

Background And Overview: The impact of digital imaging on dental practice depends upon the degree of planning conducted before implementation. Digital technologies have the potential to improve diagnosis; facilitate patient treatment procedures; and streamline storage, transfer and retrieval. These technologies also provide for secure backup of patients' image data, critical to re-establishing the practice should fire, flood or earthquake occur.

A multidisciplinary approach to treatment planning the single-implant restoration: interdisciplinary coordination.

The purpose of this article is to delineate the sequential thought process involved in a multidisciplinary approach to treatment planning the single-implant restoration. The pertinent issues involving orthodontic, surgical and restorative processes will be discussed comprehensively, with an emphasis on how communication and coordination among specialists influence the manner in which treatment is rendered.

Treatment planning for the single-tooth implant restoration--general considerations and the pretreatment evaluation.

This article reviews relevant clinical and radiographic information necessary to formulate an appropriate treatment plan for a patient requiring a single-tooth implant restoration. A step-by-step approach to collecting and analyzing this information a the pretreatment evaluation is presented. General considerations affecting implant treatment planning are discussed as are the parameters dictating ideal implant position and angulation.

The effect of ultraviolet functionalization of titanium on integration with bone.

Titanium implants are used as a reconstructive anchor in orthopedic and dental diseases and problems. Recently, ultraviolet (UV) light-induced photocatalytic activity of titanium has earned considerable and broad interest in environmental and clean-energy sciences. This study determines whether UV treatment of titanium enhances its osteoconductive capacity.

Contemporary management of infected mandibular fractures.

The treatment of infected mandibular fractures has advanced rather dramatically over the past 50 years. Immobilization with maxillomandibular fixation and/or splints, removal of diseased teeth in the fracture line, external fixation, use of antibiotics, debridement, and rigid internal fixation has played a role in management. Perhaps the most important advance was the realization that infected fractures also result from moving fragments and nonvital bone, not just bacteria.

What is cone-beam CT and how does it work?

This article on x-ray cone-beam CT (CBCT) acquisition provides an overview of the fundamental principles of operation of this technology and the influence of geometric and software parameters on image quality and patient radiation dose. Advantages of the CBCT system and a summary of the uses and limitations of the images produced are discussed. All current generations of CBCT systems provide useful diagnostic images.

Tuberous sclerosis complex: a case report.

Tuberous Sclerosis Complex (TSC) was first described in the late 1800s as a relative of neurofibromatosis, but it has since been identified as a discrete disorder. Patients with TSC typically present with facial adenomas, seizure disorder, and a developmental disability. The syndrome is caused by mutations in either chromosomes 9 or 16, both of which code for cell development and maturation.

N-Acetyl cysteine prevents suppression of oral fibroblast function on poly(methylmethacrylate) resin.

Despite the proven cytotoxicity, poly(methylmethacrylate) (PMMA) resin is one of the most frequently and extensively used materials in medical and dental fields. The study examined the potential detoxification of the resin material and restoration of the resin-induced suppression of cellular function using an antioxidant amino acid derivative, N-acetyl cysteine (NAC). Oral fibroblasts extracted from rat oral mucosa were cultured on the resin material with or without incorporation of NAC into the material.

In practice: how going digital will affect the dental office.

Background And Overview: The impact of digital imaging on dental practice depends upon the degree of planning conducted before implementation. Digital technologies have the potential to improve diagnosis; facilitate patient treatment procedures; and streamline storage, transfer and retrieval. These technologies also provide for secure backup of patients' image data, critical to re-establishing the practice should fire, flood or earthquake occur.

Ti nano-nodular structuring for bone integration and regeneration.

Nanostructuring technology has been proven to create unique biological properties in various biomaterials. Here we present a discovered phenomenon of titanium nano-nodular self-assembly that occurs during physical vapor depositions of titanium (Ti) onto specifically conditioned micro-textured titanium surfaces, and test a hypothesis that the Ti nanostructure has the potential to enhance bone-titanium integration. The nanostructure creation effectively provided geometrical undercut and increased the surface area by up to 40% compared with the acid-etched surface with microtopography.

A dental experience with the Abayudaya community in Uganda.

If anyone told me four months ago that I would be taking out teeth and caring about the future of dental health in Uganda, the land of Idi Amin and Raid on Entebbe, I'd have told them they were crazy. I was going to Kenya for Operation Smile; a string of events led me to Samson Wamani, Medical Director for the Abayudaya community in Uganda, and helped me realize there's a huge difference between dental care here in the U.S.

Restored viability and function of dental pulp cells on poly-methylmethacrylate (PMMA)-based dental resin supplemented with N-acetyl cysteine (NAC).

This study examines cytotoxicity of poly-methylmethacrylate (PMMA)-based dental temporary filling resin to dental pulp cells, and the potential amelioration of the toxicity with an anti-oxidant amino-acid, N-acetyl cysteine (NAC). Dental pulp cells extracted from rat maxillary incisors were cultured on the resin material with or without NAC incorporation, or on the polystyrene. The cultures were supplied with osteoblastic media, containing dexamethasone.

Effect of coloring with various metal oxides on the microstructure, color, and flexural strength of 3Y-TZP.

The purpose of this study was to investigate the effect of cerium and bismuth coloring salts solutions on the microstructure, color, flexural strength, and aging resistance of tetragonal zirconia for dental applications (3Y-TZP). Cylindrical blanks were sectioned into disks (2-mm thick, 25-mm in diameter) and colored by immersion in cerium acetate (CA), cerium chloride (CC), or bismuth chloride (BC) solutions at 1, 5, or 10 wt %. The density, elastic constants, and biaxial flexural strength were determined after sintering at 1350 degrees C.

Comparative study in desensitizing efficacy using the GaAlAs laser and dentin bonding agent.

Objective: To compare the clinical efficacy of the GaAlAs laser and dentin bonding agent in treating dentin hypersensitivity.

Methods: One hundred and forty teeth from 70 patients diagnosed with dentin hypersensitivity, were divided into two groups: In group I, teeth were irradiated with 30 mW GaAlAs laser for 1 min and in group II, teeth were applied with dentin bonding agent. Sensitivity was assessed by tactile and thermal tests, measured with the criteria proposed by Uchida at baseline and after treatment; immediately, at 15 and at 30 days.

N-acetyl cysteine (NAC)-assisted detoxification of PMMA resin.

Despite its proven cytotoxicity, poly-methyl methacrylate (PMMA) resin is one of the most frequently and extensively used materials in dental practice. This study hypothesized that an anti-oxidant amino acid, N-acetyl cysteine (NAC), has the potential to detoxify this material. Ten percent of the rat dental pulp cells were viable when cultured on the PMMA resin for 24 hours, while over 70% of the cells were viable on the NAC-added resin.

Dose-effect relationships for the submandibular salivary glands and implications for their sparing by intensity modulated radiotherapy.

Purpose: Submandibular salivary glands (SMGs) dysfunction contributes to xerostomia after radiotherapy (RT) of head-and-neck (HN) cancer. We assessed SMG dose-response relationships and their implications for sparing these glands by intensity-modulated radiotherapy (IMRT).

Methods And Materials: A total of 148 HN cancer patients underwent unstimulated and stimulated SMG salivary flow rate measurements selectively from Wharton's duct orifices, before RT and periodically through 24 months after RT.

Trabecular bone deterioration in col9a1+/- mice associated with enlarged osteoclasts adhered to collagen IX-deficient bone.

Introduction: Short collagen IX, the exclusive isoform expressed by osteoblasts, is synthesized through alternative transcription of the col9a1 gene. The function of short collagen IX in bone was characterized in col9a1-null mutant mice.

Materials And Methods: Trabecular bone morphometry of lumbar bones and tibias was evaluated by muCT and nondecalcified histology.

Implant replacement of the maxillary central incisor utilizing a modified ceramic abutment (Thommen SPI ART) and ceramic restoration.

Unlabelled: The prosthetic restoration of a missing anterior tooth with a dental implant is a challenge. Treatment coordination with a multidisciplinary team is critical in the successful outcome of this type of patient treatment. Newer surgical treatment modalities in the management of hard and soft tissues are becoming common, with very good predictability and long-term stability.

Apoptotic and inflammation markers in oral mucositis in head and neck cancer patients receiving radiotherapy: preliminary report.

Goal Of Work: The aim of this study was to investigate the expression of pro-apoptotic protein p53 and anti-apoptotic proteins BCl-2 and MCl-1, as well as the expression of pro-inflammatory cytokines tumor necrosis factor (TNF) and interleukin-1beta (IL-1beta) in patients developing mucositis during radiotherapy for head and neck cancer.

Materials And Methods: Thirty-five patients receiving radiotherapy for head/neck cancer were included in this study. Patients were examined before radiotherapy.

Microtopography of titanium suppresses osteoblastic differentiation but enhances chondroblastic differentiation of rat femoral periosteum-derived cells.

Despite the clinical fact that endosseous titanium implants directly contacts periosteum, the behavior and response of the periosteum-derived cells to surface topography of titanium have rarely been studied. This study examines the effect of titanium surface microtopography on osteoblastic and possibly-modulated chondroblastic phenotypes of femoral periosteum-derived cells. Rat femoral periosteum-derived cells were cultured on either relatively smooth, machined titanium surface or acid-etched, micro-roughened titanium surface.