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This Guideline is an official statement of the European Society of Gastrointestinal Endoscopy (ESGE). It addresses the diagnosis and management of nonvariceal upper gastrointestinal hemorrhage (NVUGIH). Main Recommendations MR1.

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Article Synopsis
  • This study examined the prevalence and predictors of serrated lesions, significant precursors to colorectal cancer, among a sample of patients in Italy during colonoscopy over several months.* -
  • Out of nearly 2,500 colonoscopies conducted, 173 serrated lesions were found, making up 7% of the total, with a notable occurrence in the left colon and among serrated adenomas in the proximal colon.* -
  • Key predictors for identifying these lesions included younger patient age, right-sided colon location, non-polypoid shapes, and smaller lesion sizes, while no specific predictors were found for serrated adenomas.*
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Background: There is a lack of validated predictors on which to decide the timing of discharge in patients already hospitalized for upper nonvariceal bleeding.

Aims: Identify factors that appear to protect nonvariceal bleeders from the development of negative outcome (rebleeding, surgery, death).

Methods: Secondary analysis of two prospective multicenter studies.

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Background: Nonvariceal upper GI bleeding (NVUGIB) that occurs in patients already hospitalized for another condition is associated with increased mortality, but outcome predictors have not been consistently identified.

Objective: To assess clinical outcomes of NVUGIB and identify predictors of mortality from NVUGIB in patients with in-hospital bleeding compared with outpatients.

Design: Secondary analysis of prospectively collected data from 2 nationwide multicenter databases.

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Background: Nonulcer causes of bleeding are often regarded as minor, ie, associated with a lower risk of mortality.

Objective: To assess the risk of death from nonulcer causes of upper GI bleeding (UGIB).

Design: Secondary analysis of prospectively collected data from 3 national databases.

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