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Objective: Although several clinical practice guidelines have been developed in the last decades, cancer pain management is still deficient. The purpose of this work was to carry out a comprehensive and systematic literature review of current clinical practice guidelines on cancer pain management, and critically appraise their methodology and content in order to evaluate their quality and validity to cope with this public health issue.

Materials And Methods: A systematic review was performed in the main databases, using English, French and Spanish as languages, from 2008 to 2013.

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