435 results match your criteria: "Hospital Clínico Universitario San Juan[Affiliation]"

Objective: The objective of this study is to analyse the perspectives of screening candidates and healthcare professionals on shared decision-making (SDM) in prostate cancer (PCa) screening using the prostate-specific antigen (PSA) test.

Design: Descriptive qualitative study (May-December 2022): six face-to-face focus groups and four semistructured interviews were conducted, transcribed verbatim and thematically analysed using ATLAS.ti software.

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Treatment with pegylated nanoliposomal irinotecan (nal-IRI) plus 5-fluorouracil/leucovorin (folinic acid; 5-FU/LV) has demonstrated remarkable efficacy for metastatic pancreatic ductal adenocarcinoma (PDAC) in clinical trials. However, real-world data on the effectiveness of nal-IRI+5-FU/LV is heterogeneous and is lacking in Spain. To assess the effectiveness and safety of nal-IRI+5-FU/LV in real-life PDAC patients in Spain.

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Justification and objectives: The Spanish Academy of Dermatology and Venereology (AEDV) Psoriasis and Pediatric Working Groups (PSW and PWG) have developed a set of recommendations for the management of pediatric psoriasis based on the best available evidence and experts' opinion. Methodology: The methodology of nominal groups was followed, with help from a scoping review. A coordinator was designated, and a group of experts was selected based on their experience and knowledge on the management of psoriasis.

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Article Synopsis
  • The article reviews the 2023 activity report from the Interventional Cardiology Association of the Spanish Society of Cardiology, highlighting key trends in interventional cardiology practices in Spain.
  • A survey involving 119 hospitals revealed a slight decrease in diagnostic studies but an increase in percutaneous coronary interventions (PCI), with a notable rise in the use of drug-coated balloons and techniques for plaque modification.
  • The findings indicate a stabilization in coronary interventions while showcasing a growth in complex procedures, particularly for valvular and nonvalvular structural heart diseases, with primary PCI becoming the leading treatment for myocardial infarction.
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Introduction And Objectives: We report the results of the 2023 Spanish catheter ablation registry.

Methods: Procedural data were collected and incorporated into the REDCap platform by all participating centers through a specific form.

Results: There were 104 participating centers in 2023 compared with 103 in 2022.

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Introduction: The role of Laboratory Medicine in patient care has evolved in the last decades. The same has occurred to the laboratory model, which has evolved from a traditional model where the laboratory is merely involved in clinical decision-making to a leading model where the laboratory is not only involved but also determines decision-making. The advent of new technologies and automation of processes have enabled laboratory professionals to focus on the first and last phase of the analytical process namely, test ordering and decision-making based on laboratory results.

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Objectives: Urinary tract infections (UTIs) are common infections within the Emergency Department (ED), causing increased laboratory workloads and unnecessary antibiotics prescriptions. The aim of this study was to improve UTI diagnostics in clinical practice by application of machine learning (ML) models for real-time UTI prediction.

Methods: In a retrospective study, patient information and outcomes from Emergency Department patients, with positive and negative culture results, were used to design models - 'Random Forest' and 'Neural Network' - for the prediction of UTIs.

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Impact of education on knowledge, attitudes, and practices for gestational toxoplasmosis.

J Infect Public Health

September 2024

Molecular Parasitology Group (GEPAMOL), Biomedical Research Center, Faculty of Health Sciences, Universidad del Quindío, Armenia, Colombia. Electronic address:

Background: Toxoplasmosis is potentially avoidable, treatable, and curable by simple and direct preventive measures. Knowledge, attitudes, and practices (KAP) assessments concerning gestational toxoplasmosis were evaluated in a cohort of pregnant women from Armenia-Quindío (Colombia, South America).

Methods: This cross-sectional descriptive KAP-type study was performed with informed consent between October 2021 and March 2022.

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Objectives: To analyze the characteristics of adult patients admitted for asthma exacerbation and determine optimization, treatment adherence, and follow-up in clinics.

Methods: Patients ≥ 18 years old admitted from May 2021 to June 2023 with a primary diagnosis of asthma exacerbation were included. Patients with a secondary diagnosis of asthma exacerbation and those without a confirmed diagnosis were excluded.

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Consensus Statement from the Spanish Academy of Dermatology and Venereology (AEDV) Psoriasis Working Group (SWG) and Pediatric Working Group (PWG) on the Management of Pediatric Psoriasis.

Actas Dermosifiliogr

July 2024

Departamento de Dermatología, Hospital Universitari Germans Trias i Pujol, Germans Trias I Pujol Research Institute (IGTP), Universitat Autònoma de Barcelona, Badalona, Barcelona, España.

Justification And Objectives: The Spanish Academy of Dermatology and Venereology (AEDV) Psoriasis and Pediatric Working Groups (PSW and PWG) have developed a set of recommendations for the management of pediatric psoriasis based on the best available evidence and experts' opinion.

Methodology: The methodology of nominal groups was followed, with help from a scoping review. A coordinator was designated, and a group of experts was selected based on their experience and knowledge on the management of psoriasis.

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Article Synopsis
  • The study examined the long-term survival and discontinuation rates of subcutaneous biosimilar tumor necrosis factor inhibitors compared to their originator counterparts in patients with rheumatic diseases.
  • A total of 4162 patients received treatments, with biosimilars showing lower discontinuation rates (33.37%) compared to originators (53.32%), primarily due to inefficacy.
  • Factors like female sex and obesity increased the risk of discontinuation, but when looking specifically at reasons for stopping the medication, no significant differences were found between biosimilars and originators in terms of long-term survival rates.
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Objectives: To show the procalcitonin (PCT) test demand from an emergency department (ED) over several years, to decrease PCT measurement via a computerized algorithm based on C-reactive protein (CRP) value, and to evaluate the subsequent economic savings.

Study Design: A cross-sectional study was performed from January 1, 2018, to May 31, 2019, to evaluate an intervention to avoid PCT measurement in the ED of Hospital Universitario San Juan in Alicante in Spain, when CRP values are low.

Methods: A PCT result of at least 1.

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[When should a patient with obesity be referred to endocrinology? Current indications for bariatric surgery].

Aten Primaria

July 2024

Departamento de Medicina, Universidad Miguel Hernández, Campus de San Juan de Alicante, Alicante, España; Unidad de Investigación, Hospital Universitario San Juan de Alicante, Alicante, España.

Bariatric surgery (BS) has been shown to be effective and efficient, but only 1% of selected patients will ever receive it. Compared to medical treatment of obesity, BS has demonstrated greater long-term sustained weight loss, a reduction in both total and cardiovascular (CV) mortality, improvement or remission of CV risk factors and other comorbidities associated with obesity, as well as improved mobility and quality of life. BS presents similar risks to other abdominal surgeries, with obesity as an added risk factor.

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Article Synopsis
  • - Juvenile xanthogranuloma is the most common type of non-Langerhans cell histiocytosis seen in children, usually appearing as yellowish papules on areas like the head, neck, and upper trunk.
  • - While most cases present as solitary lesions, some patients may have multiple lesions, which can sometimes be associated with other health issues.
  • - A case study of a 2-month-old girl with 22 papules showcases the importance of monitoring for systemic disease in patients with multiple juvenile xanthogranulomas to ensure proper management.
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Article Synopsis
  • The study aimed to understand the clinical experiences of childhood-onset non-infectious uveitis by analyzing data from 507 patients across 21 hospitals in a national registry.
  • Most cases were classified as immune disease-associated uveitis and juvenile idiopathic arthritis-associated uveitis, predominantly affecting young females, while idiopathic uveitis and pars planitis occurred more in older children without a strong sex bias.
  • The findings highlighted a variety of ocular complications linked to different types of uveitis, with juvenile idiopathic arthritis cases showing better visual outcomes, whereas idiopathic uveitis and pars planitis were associated with more severe complications and the need for systemic treatments.
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Introduction: Several barriers to optimal care in axial spondyloarthritis (axSpA) exist, which is detrimental to patient outcomes. The Rheumacensus programme aimed to identify how the standard of care (SoC) and treatment ambition for patients with axSpA could be elevated, from the unique perspective of three key stakeholders from across Europe: patients, healthcare professionals (HCPs) and payors.

Methods: Rheumacensus followed three phases: an insights-gathering workshop to identify current unmet needs in axSpA and an area of focus, a modified Delphi process to gain consensus on improvements within the agreed area of focus, and a Consensus Council (CC) meeting to generate 'Calls to Action' (CTA) to highlight the changes needed to elevate the SoC for patients with axSpA.

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Article Synopsis
  • - This article is the second part of a series focused on the histopathological features and differential diagnoses of cystic and pseudocystic structures found in skin biopsies.
  • - It specifically discusses various types of cysts, including ciliated cutaneous cysts, branchial cysts, Bartholin's cysts, thymic cysts, and more.
  • - Additionally, the article covers related structures like mucoceles, ganglion cysts, and myxoid pseudocysts found in the ear and fingers.
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Article Synopsis
  • The study examined how clinical management of nonST-segment elevation myocardial infarction (NSTEMI) differs between men and women, focusing on in-hospital events based on biological sex.
  • A total of 1,020 patients were enrolled, with women being older and frailer on average; they were less likely to undergo timely coronary angiography compared to men.
  • Despite differences in prescribed antithrombotic therapies, there were no significant disparities in the rates of coronary revascularization or in-hospital cardiovascular events between the sexes.
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Background: This study aimed to validate the role of the D-dimer to lymphocyte ratio (DLR) for mortality prediction in a large national cohort of hospitalized coronavirus disease 2019 (COVID-19) patients.

Methods: A retrospective, multicenter, observational study that included hospitalized patients due to SARS-CoV-2 infection in Spain was conducted from March 2020 to March 2022. All biomarkers and laboratory indices analyzed were measured once at admission.

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Objective: Readmission for COVID-19 is associated with high mortality, saturation of health services, and high costs. This study aimed to assess the incidence and risk factors of readmissions in COVID-19 patients in a regional hospital of Spain from February 2020 to March 2021.

Methods: A retrospective cohort study describing the characteristics of adult patients readmitted within thirty days of discharge after being infected with SARS-CoV-2 was carried out.

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