1,529 results match your criteria: "Hospital Clínico Universitario San Cecilio[Affiliation]"
Unexpected radiological presentation in allergic bronchopulmonary aspergillosis: multiple lung masses.
Thorax
January 2025
Pneumology Department, Hospital Universitario San Cecilio, Granada, Spain.
OX40: A promising therapeutic target in moderate-to-severe atopic dermatitis.
Actas Dermosifiliogr
December 2024
Servicio de Dermatología, Hospital Universitario San Cecilio, Granada. Instituto Biosanitario de Granada (ibs.GRANADA), Spain. Electronic address:
Evaluating MicroRNAs as Diagnostic Tools for Lymph Node Metastasis in Breast Cancer: Findings from a Systematic Review and Meta-Analysis.
Crit Rev Oncol Hematol
December 2024
GENYO, Centre for Genomics and Oncological Research, Pfizer/University of Granada/Andalusian Regional Government, Liquid biopsy and Cancer Interception group, PTS Granada, Avenida de la Ilustración 114, 18016, Granada, Spain; Biomedical Research Institute IBS-Granada. Avda. de Madrid, 15, 18012, Granada, Spain; Unidad de Patología Mamaria. Servicio de Cirugía General y Aparato Digestivo. Hospital Universitario San Cecilio. Granada; Integral Oncology Division, Virgen de las Nieves University Hospital, Av. Dr. Olóriz 16, 18012, Granada, Spain; Molecular lab. Unit of Pathological Anatomy. University Hospital Virgen de las Nieves. 18016. Granada, Spain. Electronic address:
Lymph node metastasis (LNM) significantly affects the prognosis and clinical management of breast cancer (BC) patients. This systematic review and meta-analysis aim to identify microRNAs (miRNAs) associated with LNM in BC and evaluate their potential diagnostic and prognostic value. Following PRISMA guidelines, a comprehensive literature search was conducted in PubMed, Web of Science, and SCOPUS databases, to assess the role of miRNAs in LNM BC.
View Article and Find Full Text PDFQ fever as a cause of fever of unknown origin in a patient on hemodialysis.
Nefrologia (Engl Ed)
January 2024
Pathology Unit, Hospital Universitario San Cecilio, Granada, Spain.
Importance: Although clinical practice guidelines exist for the treatment of infantile hemangiomas (IHs), recommendations are heterogeneous, and wide practice variations in IH management have been reported.
Objective: To analyze the degree of agreement in treatment choices for IH among pediatric dermatologists in North America and Europe and assess whether there are differences across IH risk categories.
Design, Setting, And Participants: This cross-sectional interrater and intrarater agreement study was conducted through a survey based on the Spanish Academy of Dermatology and Venereology IH prospective cohort.
Strategies for the Fortification of Human Milk in Preterm Infants: A Systematic Review.
Cureus
November 2024
Pediatrics and Neonatology, Hospital Universitario San Cecilio, Granada, ESP.
Breast milk is the best source of nourishment for both full-term and preterm newborns. However, in preterm newborns, exclusive breastfeeding can lead to nutritional deficiencies, with short- and long-term consequences on growth and neurocognitive development. Breast milk fortification is a widely used strategy to provide an adequate nutritional profile to these patients.
View Article and Find Full Text PDF[Scombroidosis. A diagnosis to consider].
Semergen
December 2024
Servicio de Dermatología, Hospital Universitario San Cecilio, Instituto de Investigación Biosanitaria (ibs) de Granada, Granada, España. Electronic address:
Acute pancreatitis due to fishbone.
Rev Esp Enferm Dig
December 2024
General and Digestive Surgery, Hospital Clínico Universitario San Cecilio .
A 68-year-old woman with obesity and ulcerative colitis history, referred to the emergency department and transferred to the ICU, with severe epigastric belt-like abdominal pain (requiring opiates) with sudden onset 10 hours after the last meal. The clinical exploration presented painful abdomen with epigastrium peritoneal irritation. Laboratory tests showed elevated amylase (2600 U/l) and lipase (1127 U/l), with leukocytosis and neutrophilia.
View Article and Find Full Text PDFAllergy and autoinflammation drive persistent systemic inflammatory response in Meniere Disease: A longitudinal study.
Clin Immunol
November 2024
Meniere's Disease Neuroscience Research Program, Faculty of Medicine & Health, School of Medical Sciences, The Kolling Institute, The University of Sydney, Sydney, New South Wales, Australia; Division of Otolaryngology, Department of Surgery, Instituto de Investigación Biosanitaria, ibs.GRANADA, Granada, Universidad de Granada, Granada, Spain; Sensorineural Pathology Programme, Centro de Investigación Biomédica en Red en Enfermedades Raras, CIBERER, Madrid, Spain.
Background: Meniere disease (MD), an inner ear disorder influenced by genetic and environmental factors, potentially leads to chronic inflammation. This study evaluates whether inflammation in MD patients is driven by allergy or autoinflammation.
Methods: 2-year longitudinal study.
Anti-OX40 Biological Therapies in the Treatment of Atopic Dermatitis: A Comprehensive Review.
J Clin Med
November 2024
Dermatology Department, Hospital Universitario San Cecilio, 18016 Granada, Spain.
Article Synopsis
- Recent developments in understanding AD have highlighted the OX40 receptor's role, leading to new treatments that block the OX40 ligand, which have shown considerable improvement in patients with moderate to severe AD.
- A thorough review of anti-OX40 treatments suggests they could be a promising option for AD management, but further studies are necessary to evaluate their long-term effectiveness in treating the disease.
Cervical Degenerative Myelopathy is an Unexpected Risk Factor for Hip Fractures.
Clin Spine Surg
November 2024
Department of Orthopaedics, Lenox Hill Hospital, Northwell Health, New York, NY.
Article Synopsis
- The study was a cross-sectional analysis aimed at evaluating if degenerative cervical myelopathy (DCM) contributes to the risk of major fragility fractures, particularly hip fractures, in older patients.
- Researchers targeted patients aged over 65 who had experienced hip fractures, finding that 15.6% showed signs of myelopathy, and the confirmed prevalence of DCM was estimated at 10.5%.
- The findings suggest that specific clinical signs such as hypertonic reflexes and cervical pain are important for diagnosing DCM, indicating a potentially significant link between DCM and hip fractures in the elderly.
[Translated article] Trigeminal Trophic Syndrome: A Diagnosis to Be Kept in Mind.
Actas Dermosifiliogr
November 2024
Servicio de Dermatología, Hospital Universitario San Cecilio, Granada, Spain.
Effects of an intervention with EVOO and physical exercise in systemic lupus erythematosus patients: Efinutriles trial protocol.
Contemp Clin Trials
January 2025
Department of Nursing, Faculty of Health Sciences, University of Granada, 18071 Granada, Spain; MP07-Bases Fisiopatología y Terapéutica Médica, Instituto de Investigación Biosanitaria (ibs.GRANADA), 18014 Granada, Spain.
Article Synopsis
- The study explores how combining extra virgin olive oil (EVOO) and a physical exercise program can potentially improve health outcomes for patients with systemic lupus erythematosus (SLE).
- It involves a 24-week clinical trial with 90 participants split into three groups: a control group, one taking EVOO supplements, and one taking both EVOO and participating in a health promotion and exercise program.
- The trial aims to assess various health metrics like disease activity, cardiovascular risk, and physical fitness, to determine if this combined approach offers significant benefits for SLE patients.
Clinical-Epidemiological Profile, and Treatment Response in Relation to Associated Atopic Comorbidity in Atopic Dermatitis. Experience From the BIOBADATOP Registry.
Actas Dermosifiliogr
November 2024
Servicio de Dermatología, Hospital Universitari Germans Trias i Pujol, Germans Trias i Pujol Research Institute (IGTP), Badalona, Barcelona, España; Departament de Medicina, Universitat Autònoma de Barcelona (UAB), Barcelona, España.
Article Synopsis
- A study was conducted on patients with atopic dermatitis (AD) to explore the impact of atopic comorbidities like asthma and allergic rhinitis on their treatment response.
- Data was collected from the BIOBADATOP registry, involving 509 patients, mostly adults with severe AD, and analyzed for associations between atopic comorbidities and clinical characteristics.
- Results indicated that patients with personal atopic comorbidities had more severe symptoms and a higher history of treatments, but no significant differences in treatment response were found after 6 and 12 months, suggesting a need for longer follow-up.
«Butterfly» or Malar Rash: Not Everything Is Lupus.
Actas Dermosifiliogr
November 2024
Anatomía Patológica, Complejo Universitario Asistencial de Salamanca, Salamanca, España.
Unveiling the Predictive Model for Macrovascular Complications in Type 2 Diabetes Mellitus: microRNAs Expression, Lipid Profile, and Oxidative Stress Markers.
Int J Mol Sci
November 2024
Department of Biochemistry and Molecular Biology I, Faculty of Science, University of Granada, 18071 Granada, Spain.
Article Synopsis
- This study analyzed new circulating markers related to macrovascular complications (MVC) in patients with type 2 diabetes mellitus (T2DM) by comparing controls, patients with T2DM, and those with T2DM and vascular complications.
- Results showed significant differences in the expression of specific microRNAs (miRs) between groups, particularly in miR-126a-3p, which was decreased in patients with vascular complications.
- The study identified predictive models using various biomarkers, including HbA1c, creatinine, total cholesterol, and specific miRs, suggesting new avenues for understanding and predicting MVC in individuals with T2DM.
Selective Digestive Decontamination: A Comprehensive Approach to Reducing Nosocomial Infections and Antimicrobial Resistance in the ICU.
J Clin Med
October 2024
Critical Care Department, Hospital Universitario San Cecilio, 18016 Granada, Spain.
Article Synopsis
- Multidrug-resistant (MDR) bacteria are a major global health issue, particularly in intensive care units (ICUs) where high antibiotic use contributes to resistance.
- This study evaluated the effects of a Selective Digestive Decontamination (SDD) protocol on antibiotic use and colonization by carbapenemase-producing Enterobacterale (CPE) in an ICU over two years.
- Results showed that implementing SDD significantly reduced overall antibiotic consumption (especially carbapenems) and colonization rates of CPE, indicating it could be an effective approach to combat antimicrobial resistance in critical care without promoting MDR bacteria.
Platelet Responses After Tapering and Discontinuation of Fostamatinib in Patients with Immune Thrombocytopenia: A Continuation of the Fostasur Study.
J Clin Med
October 2024
Hospital de la Serranía de Ronda, 29400 Málaga, Spain.
Article Synopsis
- Fostamatinib is an approved treatment for adults with chronic immune thrombocytopenia (ITP) but there's limited research on tapering doses and achieving remission after stopping the drug.
- A study involving 61 patients examined the safety and effectiveness of fostamatinib during and after dose tapering, noting that complete platelet response was typically achieved within 28 days.
- Results showed that most patients maintained platelet counts above 100 × 10/L after discontinuation, with a low relapse rate, suggesting that tapering could lead to sustained remission, though further research on tapering strategies is needed.
Medical Devices in Patients With Diabetes and Contact Dermatitis.
Actas Dermosifiliogr
October 2023
Unidad de Eczema de Contacto e Inmunoalergia. Servicio de Dermatología. Hospital Universitario San Cecilio, Granada, Spain. Electronic address:
Article Synopsis
- The rise of glucose sensors and insulin pumps has improved diabetes management, but there's been an increase in contact dermatitis cases linked to these devices due to certain allergens.* -
- Isobornyl acrylate (IBOA) is a major allergen found in some glucose sensors, leading to its removal from specific products, yet it still appears in many others.* -
- The potential benefits of these diabetes devices can be overshadowed by allergic reactions, prompting dermatologists to work with endocrinologists and manufacturers to find alternative solutions for affected patients.*
Dermatology is one of the oldest specialties and yet one of the most innovative and constantly evolving ones, too [...
View Article and Find Full Text PDF[Translated article] Five-Case Report Series of Dermofat Graft in Nasal Alar Surgical Defect Reconstruction.
Actas Dermosifiliogr
October 2024
Servicio de Dermatología, Hospital Universitario San Cecilio, Granada, Spain.
[Translated article] Real-World Safety and Efficacy Profile of Baricitinib in Patients With Atopic Dermatitis: a Multicenter Retrospective Trial From Four Spanish Hospitals in Andalusia.
Actas Dermosifiliogr
October 2024
Servicio de Dermatología, Hospital Universitario San Cecilio, Granada, Spain.
Patch test results to the Spanish baseline patch test series according to age groups: A multicentric prospective study from 2019 to 2023.
Contact Dermatitis
October 2024
Servicio de Dermatología, Hospital del Mar Research Institute, Barcelona, Spain.
Article Synopsis
- Patch test outcomes can be affected by age, but there are mixed findings on how age impacts these results.
- The study involved over 13,000 patients and revealed that middle-aged adults (31-65 years) had the highest rates of positive skin sensitisation results, particularly for certain substances like nickel and potassium dichromate.
- Overall, while age does influence some patch test results, most allergens showed consistent reactivity across ages, underscoring the importance of standard testing regardless of age.
[Translated article] Link Between Dermatology and Preventive Medicine: Has the Shingles Vaccination Changed the Overall Landscape?
Actas Dermosifiliogr
January 2025
Servicio de Medicina Preventiva, Hospital Universitario San Cecilio, Granada, España.
[Translated article] Real-World Clinical, Psychosocial and Financial Burden of Atopic Dermatitis: Results from the Spanish Cohort of the MEASURE-AD Trial.
Actas Dermosifiliogr
January 2025
Servicio de Dermatología, Hospital Universitario de Basurto, Bilbao, Spain.
Article Synopsis
- * The MEASURE-AD trial was conducted to gather comprehensive data on the burden of AD, using both patient and physician feedback, focusing on adults with moderate-to-severe cases.
- * Results from the Spanish cohort revealed that patients with higher disease severity (EASI scores 21.1-72) experienced greater symptom burden, mental health issues, reduced quality of life, increased healthcare usage, and higher out-of-pocket costs compared to those with lower severity scores.