788 results match your criteria: "Hospital Central del Instituto de Previsión Social[Affiliation]"

Background: The COVID-19 pandemic's long-term mental health implications are increasingly concerning, especially among patients suffering post-acute sequelae of SARS-CoV-2 infection: Long COVID (LC) patients.

Aim: This study explores the presence and distribution of anxiety, depression, and stress in LC individuals with cognitive complaints in northern Barcelona (Spain).

Design & Settings: This cross-sectional study involved 155 diagnosed LC individuals from the "Aliança ProHEpiC-19 Cognitiu (APC)" project.

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Objectives: To develop an EULAR training model for education in synovial tissue biopsy (STB) under ultrasound guidance (UG) following a stepwise approach: (1) development of educational material on UGSTB in large and small joints; (2) assessment of the validity, reliability and feasibility of the UGSTB educational procedure on cadaveric specimens; (3) validation of this procedure in live patients.

Methods: Using a nominal group (NG) and a DELPHI consensus methodology, educational audio-visual (AV) material and minimal requirements for education in UGSTB were developed by an expert panel. Then the experts performed an UGSTB on cadaveric joints using the developed approach.

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Background And Objectives: Non-viral bloodborne diseases are a group of infections that are a public health problem worldwide. The incidence of diseases such as brucellosis and syphilis is increasing in the Americas and Europe. Chagas disease is an endemic problem in Latin America, the United States and Europe.

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Objective: Being Mexico a very diverse developing country, the access to health care varies among geographical regions. We aimed to assess the differences in clinical features and treatment prescription in 3 regions of Mexico using data from the Mexican Adverse Events Registry (BIOBADAMEX).

Methods: We included all BIOBADAMEX patients from 2016 to 2023, compared the prescription patterns, the sociodemographic, clinical, and treatment characteristics between the northern (NR), central (CR), and southern regions (SR), and addressed the treatment survival by calculating hazards ratios (HRs).

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Objective: To develop a treatment algorithm for patients with penicillin allergy.

Methods: Retrospective study, carried out in adult patients with penicillin allergy, who were in group 3 or 4 of the established classification, and attended the outpatient clinic of the Department of Pulmonology and Allergy of the Central Hospital of the Social Security Institute, between January 2021 and December 2022. Each patient underwent an amoxicillin provocation test, after obtaining informed consent.

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Objective: To analyse the interrater reliability of the NEUMOBACT checklist and verify whether consistent results are reproducible.

Methods: A validation study with a cross-sectional design, compliant with the GRRAS checklist, among ICU nurses attending a SIMULAZERO course with an Objective Structured Clinical Evaluation simulation format, to verify transfer from theory to clinical practice of knowledge and skills in ventilator-associated pneumonia (VAP) and catheter-related bacteraemia (CRB) prevention. A minimum sample size of 111 pairs of nurse raters was calculated.

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There is a pressing need for accessible biomarkers with high diagnostic accuracy for Alzheimer's disease (AD) diagnosis to facilitate widespread screening, particularly in underserved groups. Saliva is an emerging specimen for measuring AD biomarkers, with distinct contexts of use that could complement blood and cerebrospinal fluid and detect various analytes. An interdisciplinary, international group of AD and related dementias (ADRD) researchers convened and performed a narrative review of published studies on salivary AD biomarkers.

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Paediatric critical care units are designed for children at a vulnerable stage of development, yet the evidence base for practice and policy in paediatric critical care remains scarce. In this Health Policy, we present a roadmap providing strategic guidance for international paediatric critical care trials. We convened a multidisciplinary group of 32 paediatric critical care experts from six continents representing paediatric critical care research networks and groups.

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Effect of dietary protein on serum hepcidin and iron in adults with obesity and insulin resistance: A randomized single blind clinical trial.

Nutr Metab Cardiovasc Dis

November 2024

Departamento de Fisiología de la Nutrición, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (INCMNSZ), Ciudad de México, Mexico. Electronic address:

Background And Aims: Both obesity and iron deficiency are public health problems. The association between the two problems could be explained by chronic low-grade inflammation in obesity, which could stimulate hepcidin expression and modify iron concentration that the consumption of high-protein diets could prevent. Thus, this study aimed to compare the effects of high-protein diets with a predominance of animal or vegetable protein on serum hepcidin and iron concentrations in adults with obesity.

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X-chromosome-wide association study for Alzheimer's disease.

Mol Psychiatry

December 2024

Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, LabEx DISTALZ - U1167-RID-AGE Facteurs de Risque et Déterminants Moléculaires des Maladies Liées au Vieillissement, Lille, France.

Article Synopsis
  • A study was conducted to investigate the X-chromosome's role in Alzheimer's Disease (AD), which had been overlooked in previous genome-wide association studies.
  • The research included 115,841 AD cases and 613,671 controls, considering different X-chromosome inactivation (XCI) states in females.
  • While no strong genetic risk factors for AD were found on the X-chromosome, seven significant loci were identified, suggesting areas for future research.
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Digital infrared thermography and machine learning for diabetic foot assessment: thermal patterns and classification.

J Diabetes Metab Disord

December 2024

Coordinación para la Innovación y Aplicación de la Ciencia y la Tecnología, Universidad Autónoma San Luis Potosí, San Luis Potosí, SLP Mexico.

Objectives: Digital infrared thermography is a noninvasive tool used for assessing diseases, including the diabetic foot. This study aims to analyze thermal patterns of the foot sole in patients with type 2 diabetes mellitus using thermography and explore correlations with clinical variables. Additionally, a machine learning approach was developed for classification.

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Background: Acute hemorrhagic leukoencephalitis (AHLE) or Weston-Hurst syndrome is a rare and severe variant of acute disseminated encephalomyelitis (ADEM). It causes fulminant hemorrhagic demyelination of the central nervous system, and has high mortality and morbidity. Due to the increase in cases and to its high rate of mortality, we decided to make a series of cases and a review of the disease.

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[Radiological clinical profile of multiple cranial neuropathy and recurrence risk factors].

Rev Med Inst Mex Seguro Soc

September 2024

Instituto Politécnico Nacional, Escuela Superior de Medicina, Sección de Estudios de Posgrado e Investigación. Ciudad de México, México.

Background: Multiple cranial neuropathies (MCN) are the dysfunction of 2 or more cranial nerves, simultaneously or sequentially. The most common causes are tumors, followed by vascular and traumatic causes, central nervous system infections and Guillain-Barré syndrome and its variants.

Objective: To identify the radiological clinical profile of MCN in patients of a tertiary-care hospital.

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A ten-year experience with the diagnosis of von Willebrand disease in Mexico based on a cost-effective strategy.

Arch Med Res

November 2024

Unidad de Investigacion Médica en Trombosis, Hemostasia y Aterogénesis, Instituto Mexicano del Seguro Social, Mexico City, Mexico. Electronic address:

Background: Von Willebrand disease (VWD), is the most common inherited bleeding disorder worldwide, but its diagnosis is complicated, expensive, and poorly evaluated in several countries.

Objective: To report our long-term experience with the diagnosis of VWD based on a cost-effective strategy.

Methods: We studied 802 Mexican patients, men and women, children, and adults, with clinical suspicion of VWD.

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Background: Neuromyelitis optica (NMO or Devic's syndrome), characterized by acute attacks of optic neuritis and transverse myelitis, is associated with antiaquaporin 4 antibodies (anti-NMO-IgG) and it has a higher prevalence in non-Caucasian populations, where multiple sclerosis is less common.

Clinical Case: 41-year-old man, with no significant personal medical history, presented with clinical symptoms including paresthesias in the right hemibody and homonymous hemianopsia in the left eye. Three weeks later, he developed lumbalgia associated with paresthesias in both lower limbs up to the T7 sensory level, as well as acute urinary retention, followed by paraplegia.

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Article Synopsis
  • Urinary tract infections and bacteriuria are prevalent among adolescents, with rising antibiotic resistance posing a significant health risk.
  • A study in Tlaxcala, Mexico, involved 905 adolescents aged 11 to 18 and found a bacteriuria prevalence of 3.4%, primarily affecting asymptomatic individuals.
  • Escherichia coli was the most common pathogen identified, with notable resistance to antibiotics, and risk factors included being female, sexually active, using contraceptives, and consuming sweetened drinks.
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[Erythrocyte morphological alterations as predictors of kidney injury severity].

Rev Med Inst Mex Seguro Soc

November 2024

Instituto Mexicano del Seguro Social, Órgano de Operación Administrativa Desconcentrada Estatal Puebla, Hospital General de Zona No. 20. Puebla, Puebla, México.

Background: Chronic kidney disease (CKD) is characterized by decreased renal function. Detecting and treating CKD in its early stages is essential for prognosis and use of less invasive renal treatments. CKD can manifest with different markers of renal damage.

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[Primary central nervous system lymphoma in immunocompetent patient: A case report].

Rev Med Inst Mex Seguro Soc

July 2024

Instituto Mexicano del Seguro Social. Centro Médico Nacional Siglo XXI, Hospital de Especialidades "Dr. Bernardo Sepúlveda Gutiérrez", Servicio de Medicina Interna. Ciudad de México, México.

Article Synopsis
  • Primary central nervous system lymphoma (PCNSL) is a rare, aggressive form of lymphoma occurring in the brain and spinal cord, primarily in immunocompromised individuals, but it can also affect immunocompetent patients.
  • A case study of a 69-year-old man showed typical symptoms and imaging findings for PCNSL, leading to a diagnosis confirmed by brain biopsy, but he did not respond to chemotherapy.
  • Timely recognition and treatment of PCNSL are crucial, especially in patients over 60 years old presenting with multiple brain lesions, due to the generally poor prognosis associated with the disease.
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Background: Lifestyle changes in adolescents are characterized by a poor diet which means rich in fat and cholesterol, and it is associated with the development of dyslipidemia, which is considered one of the main risk factors for cardiovascular disease in adulthood.

Objective: To identify the association between risk eating habits and the presence of dyslipidemia in adolescents at the primary health care level.

Material And Methods: Cross-sectional, analytical, and retrospective study, which included adolescents aged 10-17 years.

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[Mpox in humans: an overview of the 2022-2023 epidemic].

Rev Med Inst Mex Seguro Soc

March 2024

Instituto Mexicano del Seguro Social, OOAD Puebla, Coordinación de Planeación y Enlace Institucional. Puebla, Puebla, México.

Monkeypox, also known as Mpox, is a zoonotic disease endemic to central and western Africa. Following the successful eradication of human smallpox, Mpox has emerged as the primary poxvirus-related illness. In May 2022, an outbreak of Mpox was reported in the United Kingdom.

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Article Synopsis
  • The update of the Mexican Guidelines for the Treatment of Systemic Lupus Erythematosus has been developed with input from various experts across the country.
  • The new guidelines follow the GRADE system, which helps in evaluating the quality of evidence for healthcare recommendations.
  • Key new topics included in the update are vaccines, pregnancy, and cardiovascular risk, which were not addressed in the previous guidelines from 2017.
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[Severe coronavirus-2 infection background for cardiovascular complications].

Rev Med Inst Mex Seguro Soc

March 2024

Instituto Mexicano del Seguro Social, Centro Médico Nacional del Bajío, Hospital de Especialidades No. 1, División de Investigación en Salud. León, Guanajuato, México.

Article Synopsis
  • Covid-19 infections can lead to long-term cardiovascular issues, potentially due to inflammation and damage from the virus, but it's unclear if severe cases pose a higher risk.
  • A study analyzed 988 patients to compare cardiovascular complications in those with severe covid-19 versus those without, using electronic medical records for data collection.
  • Results indicated that severe covid-19 is linked to increased rehospitalization for heart-related issues like endocarditis and arrhythmias, showing a lasting negative impact on cardiovascular health.
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