4 results match your criteria: "Hospital Center University De Rouen[Affiliation]"
Performing High-Quality Sublobar Resections: Key Differences Between Wedge Resection and Segmentectomy.
Cancers (Basel)
November 2024
Department of General and Thoracic Surgery, Hospital Center University De Rouen, 1 Rue de Germont, F-76000 Rouen, France.
Lung cancer remains the leading cause of cancer-related deaths worldwide. The introduction of targeted treatments and immunotherapy in lung cancer has transformed patient care by offering "precision medicine" focused on the characteristics of the disease. The same concept has emerged in lung cancer surgery.
View Article and Find Full Text PDFSquamous Cell Carcinoma of the Lung With Microsatellite Instability in a Patient With Lynch Syndrome: A Case Report.
JTO Clin Res Rep
January 2024
University of Rouen Normandy (UNIROUEN), Institut National de la Santé et de la Recherche Médicale (INSERM) U1245, Rouen, France.
Lynch syndrome is the most common autosomal dominant inherited cancer predisposing syndrome, due to mutations in DNA mismatch repair genes. The key feature of cancers in Lynch syndrome is microsatellite instability and a high risk of developing mainly colorectal and uterine cancers. However, cancers with microsatellite instability outside this spectrum, for example, lung cancer, are extremely rare.
View Article and Find Full Text PDFBeyond the Frontline: A Triple-Line Approach of Thoracic Surgeons in Lung Cancer Management-State of the Art.
Cancers (Basel)
August 2023
Department of General and Thoracic Surgery, Hospital Center University De Rouen, 1 Rue de Germont, F-76000 Rouen, France.
Article Synopsis
- * Immune checkpoint inhibitors and targeted therapies have transformed treatment for NSCLC, offering better outcomes than traditional chemotherapy, although issues with acquired resistance remain.
- * Thoracic surgery has improved through minimally invasive techniques and precision surgery, emphasizing comprehensive patient care from pre-operative support through post-treatment follow-up and potential salvage surgery options.
Incidence, Causes, and Outcomes Associated With Urgent Implantation of a Supplementary Valve During Transcatheter Aortic Valve Replacement.
JAMA Cardiol
August 2021
Department of Cardiology, Centres for Heart Valve and Cardiovascular Innovation, St Paul's and Vancouver General Hospital, Vancouver, British Columbia, Canada.
Importance: Transcatheter aortic valve replacement (TAVR) failure is often managed by an urgent implantation of a supplementary valve during the procedure (2-valve TAVR [2V-TAVR]). Little is known about the factors associated with or sequelae of 2V-TAVR.
Objective: To examine the incidence, causes, and outcomes of 2V-TAVR.