1 results match your criteria: "Hospital 'Casa Sollievo della Sofferenza' IRCSS[Affiliation]"
Re-treatment of patients with anti-HBe-positive chronic hepatitis B who relapsed after an initial course of lamivudine.
Aliment Pharmacol Ther
November 2003
Division of Gastroenterology, Hospital 'Casa Sollievo della Sofferenza' IRCSS, San Giovanni Rotondo, Italy.
Aim: To evaluate the efficacy of a long-term course of lamivudine monotherapy in patients with anti-HBe-positive chronic hepatitis B who relapsed after the first course of either lamivudine/interferon (n = 16; Group 1) or lamivudine (n = 20; Group 2).
Methods: Biochemical and virological tests were performed every 3 months. At baseline and breakthrough, the region coding for the YMDD amino acid motif was sequenced.