Novel Fuzzy Logic Scheme for Push-Based Critical Data Broadcast Mitigation in VNDN.

Vehicular Named Data Networking (VNDN) is one of the potential and future networking architectures that allow Connected and Autonomous Vehicles (CAV) to exchange data by simply disseminating the content over the network. VNDN only supports a pull-based data forwarding model, where the content information is forwarded upon request. However, in critical situations, it is essential to design a push-based data forwarding model in order to broadcast the critical data packets without any requests.

Ultrahigh sensitive and selective detection of single nucleotide polymorphism using peptide nucleic acid and ribonuclease H assembled DNA amplification (PRADA).

Early diagnosis and monitoring of cancer is the best way to increase the survival rate among patients with cancer. However, the current cancer screening technology is expensive and time-consuming; hence, cancer screening remains challenging. Therefore, developing a relatively inexpensive and high-performance analytical method is necessary.

A causal relationship between alcohol intake and type 2 diabetes mellitus: A two-sample Mendelian randomization study.

Background And Aims: We investigated whether alcohol intake has a causal relationship with type 2 diabetes mellitus (T2DM) risk in adults of the Korean Genomic Epidemiology Study using two-sample Mendelian randomization (MR) analysis.

Methods And Results: Daily alcohol intake was calculated based on the type, average amount, and frequency of alcohol consumption for six months before the interview. The participants were divided into low- and high-alcohol intake of 20 g/day.

Validation and usability study of the framework for a user needs-centered mHealth app selection.

Background: Most mHealth app users rely on an app's rankings, star ratings, or reviews, which may not reflect users' individual healthcare needs. To help healthcare providers, researchers, and users select an optimal mHealth app, the Method of App Selection based on User Needs (MASUN) 1.0 was developed and tested in prior research.

Fusion Attention Mechanism for Foreground Detection Based on Multiscale U-Net Architecture.

Foreground detection is a classic video processing task, widely used in video surveillance and other fields, and is the basic step of many computer vision tasks. The scene in the real world is complex and changeable, and it is difficult for traditional unsupervised methods to accurately extract foreground targets. Based on deep learning theory, this paper proposes a foreground detection method based on the multiscale U-Net architecture with a fusion attention mechanism.

Beneficial Effect of Blume and Wolf Administration on Acute UVB Irradiation by Alleviating Inflammation through Promoting the Gut-Skin Axis.

Bioactive compounds in some herbs can, directly and indirectly, protect against photoaging. We evaluated the effects of Blume (GE) and Wolf (PC) water extracts on ultraviolet (UV) B-induced skin lesions by acute UVB exposure in ICR mice and explored their mechanism of action. After removing the hair on the back of the mice, UVB (280-310 nm) was exposed to the back for 30 min to induce skin damage.

Comparative analysis of imaging diagnostic models for tubular basophilia and mineralization of kidney.

Background: Now that it is possible to efficiently classify and save tissue images of laboratory animals using whole-slide imaging, many diagnostic models are being developed through transfer learning with Convolutional Neural Network (CNN). In this study, transfer learning was performed to gain toxicopathological knowledge using CNN models such as InceptionV3 and Xception. For the classification of tubular basophilia and mineralization, two representative background lesions that commonly occur in toxicological studies, accuracies of diagnosis were compared using MobileNetV2, Xception and InceptionV3.

Foreground Detection Based on Superpixel and Semantic Segmentation.

Foreground detection is an essential step in computer vision and video processing. Accurate foreground object extraction is crucial for subsequent high-level tasks such as target recognition and tracking. Although many foreground detection algorithms have been proposed, foreground detection in complex scenes is still a challenging problem.

Highly Sensitive and Real-Time Detection of Zinc Oxide Nanoparticles Using Quartz Crystal Microbalance via DNA Induced Conjugation.

With the development of nanotechnology, nanomaterials have been widely used in the development of commercial products. In particular, zinc oxide nanoparticles (ZnONPs) have been of great interest due to their extraordinary properties, such as semiconductive, piezoelectric, and absorbance properties in UVA and UVB (280-400 nm) spectra. However, recent studies have investigated the toxicity of these ZnONPs; therefore, a ZnONP screening tool is required for human health and environmental problems.

Euscaphic acid relieves fatigue by enhancing anti-oxidative and anti-inflammatory effects.

Background: Oxidative stress and inflammation are involved in chronic fatigue. Euscaphic acid (EA) is an active compound of (Loquat) and has anti-oxidative effect.

Methods: The goal of present study is to prove whether EA could relieve fatigue through enhancing anti-oxidant and anti-inflammatory effects in models.

RANKL down-regulates the mast cell proliferation through inducing senescence.

An increase in the number of mast cells could contribute to inflammatory diseases and pathologic conditions. A receptor activator of NF-κB ligand (RANKL)/RANK system is one of the key signaling pathways accelerating mast cell-mediated allergic inflammatory reactions. However, the biological functions of RANKL in mast cell proliferation remains to be clarified.

Interaction of polygenic variants specific for abdominal obesity risk with energy metabolism in large Korean cohorts.

We examined the hypothesis that the genetic variants associated with abdominal obesity (AO) risk, excluding skeletal muscle mass impact, interact with lifestyle characteristics of adults aged >40 years in three cohorts from the Korean Genome and Epidemiology Study. Participants from a large city hospital-based cohort, excluding those with cancers, thyroid diseases, chronic kidney disease or brain-related diseases, were divided into AO (case; n = 17 545) and control (n = 36 283) using the cut-offs for waist circumference of 90 cm for men and 85 cm for women. The genetic variants affecting AO risk were chosen from a genome-wide association study in this cohort with obesity-related covariates, including and excluding skeletal muscle mass as a covariate.

The Influence of College Sports Services on Sports Behavioral Intentions: A Mediation Model Based on Satisfaction and Involvement.

To learn more about the impact of college sports services on student sports activity intentions, as well as the function of pleasure and involvement as a mediating factor in this process. According to the nature of the service, this study separates college sports services into basic and advanced sports two types, selects 482 students from five institutions in Hunan Province for a questionnaire survey based on spatial dimensions, and analyzes the data using a structural equation model. The findings show that (1) there is a positive correlation between college students' perception levels of basic and advanced sports services ( = 0.

Use of Observational Learning to Promote Motor Skill Learning in Physical Education: A Systematic Review.

Observational learning is an effective pedagogical approach that can influence students' motor skill development at every level of physical education (PE). This study aimed to systematically summarize the evidence on observational learning for motor skill learning in PE and to generalize the evidence on the effect of model formats and verbal cues during observational learning. An electronic search of eight databases was conducted.

FGFRL1 and FGF genes are associated with height, hypertension, and osteoporosis.

Hypertension and osteoporosis are two major disorders, which interact with each other. Specific genetic signals involving the fibroblast growth factor receptor-like 1 (FGFRL1) gene are related to high blood pressure and bone growth in giraffes. FGFRL1 is associated with cardiovascular system and bone formation.

Implementation of Disassembler on Microcontroller Using Side-Channel Power Consumption Leakage.

With the development of 5G and network technology, the usage of IoT devices has become popular. Because most of these IoT devices can be controlled by an adversary away from the administrator, several security issues such as firmware dumping can arise. Firmware dumping is the cornerstone or goal of many types of hardware hacking.

Association of Polygenic Variants with Type 2 Diabetes Risk and Their Interaction with Lifestyles in Asians.

Over the last several decades, there has been a considerable growth in type 2 diabetes (T2DM) in Asians. A pathophysiological mechanism in Asian T2DM is closely linked to low insulin secretion, β-cell mass, and inability to compensate for insulin resistance. We hypothesized that genetic variants associated with lower β-cell mass and function and their combination with unhealthy lifestyle factors significantly raise T2DM risk among Asians.

Breastfeeding mobile application for mothers with gestational diabetes mellitus: designed by mothers and experts.

Background: Mothers and babies with gestational diabetes have an increased risk of diabetes, obesity, and cardiovascular complications. Breastfeeding is known to help reduce complications in mothers and babies with gestational diabetes. However, the rate of breastfeeding among mothers with gestational diabetes is still low due to various barriers.

Sex-Based Differences in Outcomes of Coronavirus Disease 2019 (COVID-19) in Korea.

Purpose: This study examined the factors affecting mortality and clinical severity score (CSS) of male and female patients with Coronavirus Disease 2019 (COVID-19) using clinical epidemiological information provided by the Korea Disease Control and Prevention Agency.

Methods: This is a retrospective, observational cohort study. From January 21 to April 30, 2020, a total of 5624 patients who were released from quarantine or died were analyzed.

Genetic polymorphism of HLA-DRA and alcohol consumption affect hepatitis development in the Korean population.

Background: Hepatitis is an inflammation of the liver that has several potential causes; however, the genetic association has recently begun to be studied.

Objectives: Human leukocyte antigen (HLA) is an essential component of the immune response, and in this study, we conducted a correlation analysis to determine whether genetic polymorphisms of HLA and drinking habits affect hepatitis development.

Methods: Genetic polymorphisms of HLA were investigated using Korean genomic and epidemiological data.

Mitigation of Memory Impairment with Fermented Fucoidan and λ-Carrageenan Supplementation through Modulating the Gut Microbiota and Their Metagenome Function in Hippocampal Amyloid-β Infused Rats.

Attenuating acetylcholinesterase and insulin/insulin-like growth factor-1 signaling in the hippocampus is associated with Alzheimer's disease (AD) development. Fucoidan and carrageenan are brown and red algae, respectively, with potent antibacterial, anti-inflammatory, antioxidant and antiviral activities. This study examined how low-molecular-weight (MW) and high-MW fucoidan and λ-carrageenan would improve memory impairment in Alzheimer's disease-induced rats caused by an infusion of toxic amyloid-β(Aβ).

Antioxidant and Anti-Inflammatory Activity of Nakai Ethanolic Extract and Its Chemical Composition.

Many countries are endeavoring to strengthen the competitiveness of their biological resources by exploring and developing wild endemic plants. This study examined the effects of Nakai (FG) on the antioxidant and anti-inflammatory activity using an in vitro system. The bioactive components were also examined using chromatographic techniques.

Alleviation of Metabolic Disturbance by Substituting Kanjang High in for Salt through Modulation of Gut Microbiota in Estrogen-Deficient Rats.

A high salt intake may exacerbate menopausal symptoms and substituting for different types of traditionally made kanjang (TMK; soy sauce) may prevent it. This study examined whether substituting salt with lyophilized TMK containing low and high and biogenic amines in a high-fat diet might modulate the menopausal symptoms and the energy, glucose, and lipid metabolism in ovariectomized (OVX) rats. They were categorized into salt (Control), TMK with high and low biogenic amines (HBLB), TMK with high and high biogenic amines (HBHB), TMK with low and low biogenic amines (LBLB), and TMK with low and high biogenic amines (LBHB).

Development of Simultaneous Analytical Method for Imidazolinone Herbicides from Livestock Products by UHPLC-MSMS.

A simultaneous analytical method, which used LC/MSMS for imidazolinone herbicides from livestock products (egg, milk, beef, pork, and chicken) for monitoring, was developed with a QuEChERS preparation. A weighed sample (5 g) in a 50 mL conical tube was added to 0.1 M potassium phosphate dibasic solution (5 mL) and shaken for 10 min.

Effect of Modified Yukmijihwang-Tang on Sleep Quality in the Rat.

Many plants have been used in Korean medicine for treating insomnia. However, scientific evidence for their sedative activity has not been fully investigated. Thus, this study was carried out to investigate the sedative effects of the extracts of medicinal plants, including Yukmijihwang-tang and its various modified forms through the 5-HT2c receptor binding assay, and to further confirm its sleep-promoting effects and the underlying neural mechanism in rats utilizing electroencephalography (EEG) analysis.