4,034 results match your criteria: "Horseshoe Kidney"
Eur J Med Chem
November 2024
Federal Research Centre "Fundamentals of Biotechnology" of the Russian Academy of Sciences (Research Centre of Biotechnology RAS), Leninsky prospect, 33, build. 2, 119071, Moscow, Russia. Electronic address:
J Pediatr Urol
August 2024
University of California, San Francisco, Uganda. Electronic address:
J Thorac Dis
July 2024
Tianjin Key Laboratory of Cardiovascular Emergencies and Critical Care, Tianjin, China.
Background: The cardiac surgery-associated acute kidney injury (CSA-AKI) occurs in up to 1 out of 3 patients. Off-pump coronary artery bypass grafting (OPCABG) is one of the major cardiac surgeries leading to CSA-AKI. Early identification and timely intervention are of clinical significance for CSA-AKI.
View Article and Find Full Text PDFVascular
August 2024
Section of Vascular Surgery, Veterans Affairs New Jersey Healthcare System, East Orange, NJ, USA.
Objective: To assess viability and safety of preemptive treatment of type II endoleak for abdominal aortic aneurysm (AAA) repairs.
Methods: A 69-year-old man with renal fusion (horseshoe kidney) was referred for treatment of a 5.5 cm AAA.
J Clin Res Pediatr Endocrinol
August 2024
Department of Pediatric Endocrinology, School of Medicine, Marmara University, Istanbul, Türkiye.
Biochem Biophys Res Commun
December 2024
Biological and Chemical Research Center, Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093, Warsaw, Poland.
Human α1,4-galactosyltransferase (A4galt), a Golgi apparatus-resident GT, synthesizes Gb3 glycosphingolipid (GSL) and P1 glycotope on glycoproteins (GPs), which are receptors for Shiga toxin types 1 and 2. Despite the significant role of A4galt in glycosylation processes, the molecular mechanisms underlying its varied acceptor specificities remain poorly understood. Here, we attempted to elucidate A4galt specificity towards GSLs and GPs by exploring its interaction with GTs with various acceptor specificities, GP-specific β1,4-galactosyltransferase 1 (B4galt1) and GSL-specific β1,4-galactosyltransferase isoenzymes 5 and 6 (B4galt5 and B4galt6).
View Article and Find Full Text PDFJ Med Case Rep
August 2024
Manmohan Cardiothoracic Vascular and Transplant Center, Institute of Medicine, Tribhuvan University, Kathmandu, Nepal.
Background: Crossed fused renal ectopia (CFRE) is a common congenital anomaly where one kidney is positioned abnormally on the opposite side of the midline, often fused with the other kidney. However, single ureter draining crossed fused renal ectopia is a rare occurrence.
Case Report: Here, we report a case of crossed fused renal ectopia with a single ureter in a 46-year-old Nepali male who presented with history of lithuria.
Cytogenet Genome Res
October 2024
Genetic Metabolism Medical Center, Dalian Women and Children's Medical Center (Group), Dalian, China.
Anal Chem
August 2024
Department of Chemistry, Stanford University, Stanford, California 94305, United States.
Fusion of enveloped viruses with endosomal membranes and subsequent release of the viral genome into the cytoplasm are crucial to the viral infection cycle. It is often modeled by performing fusion between virus particles and target lipid vesicles. We utilized fluorescence microscopy to characterize the kinetic aspects of the transfer of influenza viral ribonucleoprotein (vRNP) complexes to target vesicles and their spatial distribution within the fused volumes to gain deeper insight into the mechanistic aspects of endosomal escape.
View Article and Find Full Text PDFRadiol Case Rep
September 2024
Departamento de Radiología e Imágenes Diagnósticas, Fundación Valle del Lili, Cali, Colombia.
The upper urinary tract is the most common human organ system affected by congenital anomalies. A Horseshoe kidney is a fusion anomaly, it can be described as a fusion across the midline of 2 distinct functioning kidneys. The incidence of renal tumors in a Horseshoe kidney is higher than in the normal population.
View Article and Find Full Text PDF68Ga-DOTA NOC PET-CT imaging has been shown to have high accuracy for the evaluation of neuroendocrine tumours. We present the case of a 59-year-old male with well differentiated gastric neuroendocrine tumour (grade II) treated with surgery. 68Ga-DOTA NOC PET/CT was performed to rule out metastasis.
View Article and Find Full Text PDFInt J Mol Sci
June 2024
Department of Anatomy, School of Medicine, University of Mostar, 88000 Mostar, Bosnia and Herzegovina.
The purpose of this study was to evaluate the spatiotemporal immunoexpression pattern of microtubule-associated protein 1 light chain 3 beta (LC3B), glucose-regulated protein 78 (GRP78), heat shock protein 70 (HSP70), and lysosomal-associated membrane protein 2A (LAMP2A) in normal human fetal kidney development (CTRL) and kidneys affected with congenital anomalies of the kidney and urinary tract (CAKUT). Human fetal kidneys (control, horseshoe, dysplastic, duplex, and hypoplastic) from the 18th to the 38th developmental week underwent epifluorescence microscopy analysis after being stained with antibodies. Immunoreactivity was quantified in various kidney structures, and expression dynamics were examined using linear and nonlinear regression modeling.
View Article and Find Full Text PDFInt Med Case Rep J
July 2024
Facultad de Medicina Matamoros, Universidad Autónoma de Tamaulipas, Matamoros, Tamaulipas, C. P. 87300, México.
Eur J Med Chem
October 2024
College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, 310058, China; Jinhua Institute of Zhejiang University, Jinhua, Zhejiang, 321299, China. Electronic address:
Since influenza virus RNA polymerase subunit PA is a dinuclear Mn dependent endonuclease, metal-binding pharmacophores (MBPs) with Mn coordination has been elucidated as a promising strategy to develop PA inhibitors for influenza treatment. However, few attentions have been paid to the relationship between the optimal arrangement of the donor atoms in MBPs and anti-influenza A virus (IAV) efficacy. Given that, the privileged hydroxypyridinones fusing a seven-membered lactam ring with diverse side chains, chiral centers or cyclic systems were designed and synthesized.
View Article and Find Full Text PDFZhonghua Bing Li Xue Za Zhi
July 2024
Department of Pathology, Beijing Friendship Hospital Affiliated to Capital Medical University, Beijing 100050, China.
In Vivo
June 2024
Department of Urology, Tokyo Women's Medical University Hospital, Tokyo, Japan.
Background: Robot-assisted partial nephrectomy (RAPN) has become the standard treatment for small renal tumors, including highly complex cases. However, applying RAPN to renal tumors in the horseshoe kidney (HSK) is clinically challenging due to malformations and complex blood supply. Herein, we present two cases of RAPN in patients with HSK treated using selective artery clamping methods.
View Article and Find Full Text PDFAnn Pediatr Cardiol
May 2024
Department of Neonatology, Kanchi Kamakoti Child Trust Hospital, Chennai, Tamil Nadu, India.
A neonate born of third-degree consanguineous marriage presented on day 12 of life with congestive cardiac failure. A male sibling died at 3 months of age, cause of which was not known. He was treated with decongestive measures and multiple inotropes.
View Article and Find Full Text PDFGenes (Basel)
May 2024
Department of Anatomy, Histology and Embryology, University of Split School of Medicine, 21000 Split, Croatia.
Approximately half of the cases of chronic kidney disease (CKD) in childhood are caused by congenital anomalies of the kidney and urinary tract (CAKUT). Specific genes were identified as having significant importance in regard to the underlying genetic factors responsible for the CAKUT phenotype, and in our research, we focused on analyzing and comparing the expression levels of ectodysplasin A2 receptor (EDA2R), protocadherin9 (PCDH9), and TNF receptor-associated factor 7 (TRAF7) proteins in the cortex and medulla of healthy control kidneys during developmental phases 2, 3, and 4. We also performed an analysis of the area percentages of the mentioned proteins in the cortical and medullary sections of healthy embryonic and fetal kidneys compared to those affected by CAKUT, including duplex kidneys (DK), horseshoe kidneys (HK), hypoplastic kidneys (HYP), and dysplastic kidneys (DYS).
View Article and Find Full Text PDFUrology
June 2024
Department of Urology, Loma Linda University Children's Hospital, Loma Linda, CA. Electronic address:
Caudal duplication syndrome is a rare congenital anomaly with various duplications of structures derived from the embryonic cloaca and notochord. A male neonate was born with diphallia, bifid scrotum, and duplicated anorectal malformation. Diagnostic and operative evaluation identified a partially duplicated right kidney with left-to-right crossed fused ectopia, bilateral hydronephrosis, 2 separate hemi-bladders, left ectopic ureter with vesicoureteral reflux, and a left rectourethral fistula.
View Article and Find Full Text PDFCureus
May 2024
Department of Radiology and Diagnostic Imaging, Hospital Universitário de Santa Maria, Santa Maria, BRA.
Crossed fused renal ectopia (CFRE) is a rare congenital anomaly in which a kidney is located on the opposite side from where its ureter connects to the bladder, merging into the other kidney. It has been linked to other rare congenital malformations, including the VACTERL association (vertebral anomalies, anal atresia, cardiac anomalies, tracheoesophageal fistula, esophageal atresia, renal anomalies, and limb abnormalities), the MURCS association (müllerian ducts, renal, and cervicothoracic spine anomalies), increased incidence of infections, obstruction, cystic dysplasia, and urolithiasis. Although the literature has documented only a small number of cases wherein CFRE coincides with neoplasia, we present the case of a 59-year-old patient with a right ectopic kidney fused to the left one and simultaneous primary renal cell carcinoma.
View Article and Find Full Text PDFJ Am Chem Soc
July 2024
Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892-0520, United States.
Double electron-electron resonance (DEER) EPR is a powerful tool in structural biology, providing distances between pairs of spin labels. When the sample consists of a mixture of oligomeric species (e.g.
View Article and Find Full Text PDFInfect Genet Evol
September 2024
HUN-REN Veterinary Medical Research Institute, Hungária krt. 21, H-1143 Budapest, Hungary.
The Eurasian beaver (Castor fiber), native to Hungary, faced local extinction in 1865 and was successfully reintroduced between mid-1980s and 2008. Despite screening programs focusing on animal health during reintroduction in other countries, information about viruses in the Hungarian beaver population remains limited. Polyomaviruses (PyVs) have been identified in various rodents, and have been detected just recently in beavers by us.
View Article and Find Full Text PDFPhys Med Biol
July 2024
CAS Key Laboratory of Molecular Imaging, Institute of Automation, Chinese Academy of Sciences, Beijing, People's Republic of China.
Magnetic particle imaging (MPI) is an emerging medical tomographic imaging modality that enables real-time imaging with high sensitivity and high spatial and temporal resolution. For the system matrix reconstruction method, the MPI reconstruction problem is an ill-posed inverse problem that is commonly solved using the Kaczmarz algorithm. However, the high computation time of the Kaczmarz algorithm, which restricts MPI reconstruction speed, has limited the development of potential clinical applications for real-time MPI.
View Article and Find Full Text PDFRadiol Case Rep
August 2024
Radiological Departments, University of Medical Science and Technology, Khartoum, Sudan.
The occurrence of triple kidneys, involving a normal kidney and a malrotation horseshoe kidney, is an extremely infrequent condition. This case report demonstrates a triple, mal-rotated horseshoe kidneys coexist with an upper junction stone, alongside a normal left kidney showing normal Doppler vascularity, as observed in an ultrasound examination for 18-year-old male complaints of diffuse periumbilical pain and burning micturition. Laboratory investigation revealed normal creatinine level, and presence of urinary tract infection.
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