Cost-effectiveness of Telemedicine Intervention for Acute Myocardial Infarction: A Systematic Review.

Background: One of the most important causes of mortality in the world is acute myocardial infarction. There are two general treatments including thrombolytic drugs and percutaneous coronary interventions. But, monitoring outpatient AMI treatment from a remote or rural location has emerged as a successful telemedicine technique.

Neonatal Nonketotic Hyperglycinemia: A Severe Case With Prenatal Indicators and Comprehensive Review of Recognition and Management.

Nonketotic hyperglycinemia (NKH), also known as glycine encephalopathy, is a rare inherited neurometabolic disorder caused by a deficiency in the glycine cleavage enzyme system (GCS), leading to the pathological accumulation of glycine in blood and cerebrospinal fluid (CSF). This case report details a neonate presenting with central apnea, profound hypotonia, and refractory seizures, alongside prenatal findings of polyhydramnios and hiccup-like fetal movements, all strongly suggestive of severe NKH. Diagnostic evaluation confirmed markedly elevated glycine levels in serum and CSF, with a CSF-to-plasma glycine ratio exceeding 0.

Compassion Competence and Patient Safety Competency in psychiatric nurses.

Background: Compassion Competence and the ability to strive to understand the suffering of patients in psychiatric ward is essential for nurses to establish effective therapeutic communication in the process of their recovery. Patient Safety Competency is of great importance for nurses to prevent adverse events and minimize errors. This study aimed to investigate the relationship between Compassion Competence and Patient Safety Competency in nurses working in psychiatric wards of Shiraz University of Medical Sciences affiliated hospitals in 2024.

Combination therapies and other therapeutic approaches targeting the NLRP3 inflammasome and neuroinflammatory pathways: a promising approach for traumatic brain injury.

Traumatic brain injury (TBI) precipitates a neuroinflammatory cascade, with the NLRP3 inflammasome emerging as a critical mediator. This review scrutinizes the complex activation pathways of the NLRP3 inflammasome by underscoring the intricate interplay between calcium signaling, mitochondrial disturbances, redox imbalances, lysosomal integrity, and autophagy. It is hypothesized that a combination therapy approach-integrating NF-κB pathway inhibitors with NLRP3 inflammasome antagonists-holds the potential to synergistically dampen the inflammatory storm associated with TBI.

Blood Cells Parameters in Second Trimester of Pregnancy and Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis.

Objective: Gestational diabetes mellitus (GDM) is one of the most common complications during pregnancy. There is inconsistency between previous studies regarding the blood and inflammatory parameters levels among pregnant women and its association with GDM. This study aimed to investigate the relationship between blood parameters in relation to GDM.

Crafting dental specialities in Iran: insights from a qualitative study.

Background: Different countries have varying dental specialities, shaped by diverse factors. The determinants influencing the development of these specialities differ between developed and developing countries. This study aimed to explore the factors contributing to the establishment of dental specialities in Iran, a developing country with a wide range of recognised dental specialities.

Use of a bioresorbable polylactide sheet (OrthoWrap Bioresorbable sheet) on tendon healing after extensor tendon repair: a controlled clinical trial.

Background: Adhesion formation poses a significant challenge for both patients and hand surgeons following tendon repair. One common strategy to prevent adhesion formation is the use of physical barriers. This study aimed to compare the outcomes of extensor tendon repair with and without the application of the OrthoWrap bioresorbable Sheet, specifically in terms of adhesion prevention.

Neuroimaging Findings of Psychosis in Alzheimer's Disease: A Systematic Review.

Background: Previous studies on neuroimaging findings in Alzheimer's disease (AD) patients with hallucinations and delusions have yielded inconsistent results. We aimed to systematically review neuroimaging findings of delusions and hallucinations in AD patients to describe the most prominent neuroimaging features.

Methods: We performed a comprehensive search in three online databases, including PubMed, Scopus, and Web of Science in June 2023.

The effect of educational intervention through sending emails on improving physical posture in female computer users of Eastern Iran: a quasi-experiment study.

Background: Musculoskeletal disorders are among the most common occupational injuries and disabilities in developing and industrialized countries. This study aims to determine the effectiveness of e-mail training to improve the physical posture of female computer users at Birjand University of Medical Sciences in Iran.

Methods: The present interventional research explores the effect of email-based training to correct the body posture of female computer users in Birjand, Iran.

Utilizing machine learning to predict the risk factors of episiotomy in parturient women.

Background: Episiotomy has specific indications that, if properly followed, can effectively prevent women from experiencing severe lacerations that may result in significant complications like anal incontinence. However, the risk factors related to episiotomy has been the center of much debate in the medical field in the past few years.

Objective: The present study used a machine learning model to predict the factors that put women at the risk of having episiotomy using intrapartum data.

Strongyloidiasis mimics duodenal lymphoma in a patient with systemic lupus erythematosus and antiphospholipid syndrome: a case report.

Background: Systemic lupus erythematosus is a multi-organ autoimmune disorder that is treated by immunosuppressive agents that weaken the immune defense against opportunistic pathogens and latent infections such as strongyloidiasis. Herein, we report the case of a 43-year-old woman known to have systemic lupus erythematosus who presented with gastrointestinal symptoms, edema, and bone pain 2 months after receiving immunosuppressive treatment.

Case Presentation: A 43-year-old Iranian female known to have systemic lupus erythematosus and antiphospholipid syndrome presented with abdominal pain, nausea, vomiting, and generalized edema.

How Can Outdoor Air Pollutants Adversely Affect the Women's Fertility? Systematic Review.

In the current century, air pollution is known as one of the most critical environmental problems and it is important to find the relations of air pollution and human health. Various air pollutants, such as volatile organic compounds (VOCs), can negatively affect women's fertility. An exhaustive electronic search was done from 2013 until July 2023 in PUBMED and The Cochrane Central Register of Controlled Trials.

Early Detection of Diabetic Nephropathy Based on Urinary and Serum Biomarkers: An Updated Systematic Review.

Diabetic nephropathy (DN) is a leading cause of chronic kidney disease (CKD) and end-stage renal disease worldwide, particularly among individuals with type 2 diabetes mellitus (T2DM). Early detection and intervention are crucial in slowing the progression of DN and improving patient outcomes. Traditional diagnostic methods, such as the measurement of albuminuria and serum creatinine, often fail to detect early renal damage because structural kidney damage may occur before albumin excretion.

Predictive power of glycated hemoglobin in detecting severity of coronary artery disease in non-diabetic patients: A cross-sectional study in southern Iran.

Background: The relationship between hemoglobin A1c (HbA1c) levels and coronary artery disease (CAD) severity is still a matter of debate in non-diabetic patients. This study aimed to determine the association between HbA1c and the severity of CAD in non-diabetic patients.

Methods: The present cross-sectional study was conducted in 2018-2019 on 133 non-diabetic patients with stable angina, unstable angina, or myocardial infarction (MI).

The evaluation of awareness, attitude, and performance of the residents of Bandar Abbas in relation to preventive behaviors and methods for controlling dengue fever.

Objective: Dengue fever is a rapidly spreading viral disease transmitted by mosquitoes, and it is becoming a global concern. This study aimed to assess the awareness, attitude, and performance of the people in Hormozgan province in carrying out preventive behaviors and dengue fever control methods.

Method: This descriptive-analytical study was conducted in 1401 in Bandar Abbas, Iran.

Ataxia With Vitamin E Deficiency: Case Series, Vitamin E Therapy Response, Founder Effect, and In Silico Analysis.

Ataxia with Vitamin E Deficiency (AVED) is a rare autosomal recessive genetic disorder, that caused by pathogenic variants in the TTPA gene, which encodes the alpha-tocopherol transfer protein. This study investigates eight patients from three consanguineous Iranian families, using exome sequencing (ES) and Sanger sequencing to identify novel pathogenic variants in the TTPA gene. Two variants were identified: c.

Distinct therapeutic effects of auraptene and umbelliprenin on TNF-α and IL-17 levels in a murine model of chronic inflammation.

Objective: To compare the anti-arthritic potential of orally administered auraptene (AUR) and umbellliprenin (UMB) in chronic inflammation by exploring the differential effect on regulating TNF-α and IL-17.

Methods & Materials: Sixty male rats were divided into ten groups, and after confirming chronic inflammation, the treatment groups received AUR or UMB orally for 9 days. On day 16, histopathological changes were evaluated.

The correlation between parenting styles and children's anxiety in the COVID-19 pandemic in Bandar Abbas in Iran.

Background: Anxiety is considered a prevalent mental disorder during childhood. Due to the significance of child psychology in critical psychological and health conditions and the fact that parenting styles may affect child health and behavioral issues in prospective life, the present study intends to explore the association of parenting styles and anxiety level among children in the COVID-19 pandemic.

Materials And Methods: The present cross-sectional study used a convenient sampling of all mothers with 5 to 12 children in Bandar Abbas in southern Iran.

Measuring Equality in Primary Health Care Budget Allocation in Iran, Using the Gini Coefficient Method.

Background: In Iran, one of the most important and influential sources for financing the Primary Health Care (PHC )is the government budget. This study was conducted with the aim of evaluating the allocation of the PHC budget and evaluating the equality in the allocation of these resources.

Methods: In this applied descriptive-analytical study, the study population included all of Iran's 31 provinces.

Predictors of treatment adherence in patients with type 2 diabetes: a cross-sectional study in Southern Iran based on Pender's Health Promotion Model using structural equation modelling.

Objectives: Treatment adherence in type 2 diabetes (T2D) is an important factor in optimal diabetes control and prevention of mortality. The present study aimed to determine the predictability of Pender's Health Promotion Model (HPM) constructs in T2D treatment adherence behaviour.

Design: The present cross-sectional and analytical study was conducted from November 2022 to January 2023.

Neoadjuvant immunotherapy and oncolytic virotherapy in HPV positive and HPV negative skin cancer: A comprehensive review.

Skin cancer is the most common new cancer among Caucasians. This cancer has different types, of which non-melanoma skin cancer is the most common type. Various factors affect this disease, one of which is viral infections, including HPV.

Explaining the causes and motivations for multiple substance use from the perspectives of users and therapists: A qualitative study.

Background: The high prevalence of multiple substance use (MSU) is concerning, given the weak awareness about this issue and the potential impact this unawareness has on the severity of substance use disorder (SUD) and treatment outcomes. The aim of this study is to identify and elucidate the causes and motivations for MSU from the viewpoints of users and therapists in this field.

Methods: In this qualitative study, the conventional content analysis approach and purposive sampling were utilized.

Should testicular sperm retrieval be implemented for intracytoplasmic sperm injection in all patients with severe oligozoospermia or cryptozoospermia?

Objective: The choice between utilizing testicular or ejaculatory sperm for intracytoplasmic sperm injection (ICSI) in men with severe oligozoospermia or cryptozoospermia is a crucial aspect of managing male infertility. This study aimed to identify a predictive factor that could guide this decision-making process.

Methods: Seventy-five infertile men with severe oligozoospermia or cryptozoospermia were included in the analysis.

A systematic review of using clinical decision support systems in corneal diseases.

Background: Corneal diseases encompass a wide spectrum of eye diseases, and are among the leading causes of blindness. The use of clinical decision support systems (CDSSs) can assist physicians in timely diagnosis of these diseases and prevent their progression.

Objective: The present study aimed to conduct a systematic review of using CDSSs in corneal diseases to identify gaps in the current knowledge and propose for future research in designing, implementation, and effective use of health information technology in ophthalmology, with a specific focus on corneal diseases.